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224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items

GSK-J1 lithium salt , CAS No.G659223

CAS: G659223 Cat. No.: G659223 Molecular Weight: 395.38
COA
GSK-J1 lithium salt - CAS No(G659223) by Aladdin Scientific
AVAILABLE TO ORDER
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
G659223-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$140.90
25mg
G659223-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$230.90
50mg
G659223-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$410.90
100mg
G659223-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$680.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Certificates（CoA,COO,BSE/TSE and Analysis Chart) Solution Calculators Reviews
🧪

Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A , with IC 50 of 60 nM towards KDM6B.

Appearance:Solid

IC50& Target:IC50: 60 nM (KDM6B)

In Vitro:GSK-J1 is selective for H3K27 demethylases of the KDM6 subfamily and specifically binds to endogenous JMJD3. GSK-J1 inhibits TNF-α production by human primary macrophages in an H3K27-dependent manner. GSK-J1 inhibits the demethylase activity of KDM5C

Biological Activity:GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A , with IC 50 of 60 nM towards KDM6B.

Specifications

Storage
Store at 2-8°C, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
Molecular Weight 395.38

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews

Customer Reviews

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