GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥98%
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Iniparib (BSI-201) is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC). Iniparib (BSI-201) is an antineoplastic originally thought to be a poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor. Recent studies indicate Iniparib is not a PARP-1 inhibitor, and its mechanism of action is currently unknown.
BSI-201(Iniparib) is a potent PARP1 inhibitor with strong anti-neoplastic effect.Non-selective modifier of cysteine-containing proteins.\xa0Able to\xa0inhibit ionizing radiation-induced single-strand breaks (SSBs) repair in vitro . No ability to inhibit P
Storage
Room temperature
Shipped In
Normal
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Reactive nitro radical
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as 4-halobenzoic acids and derivatives. These are benzoic acids or derivatives carrying a halogen atom at the 4-position of the benzene ring.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Jinbo Ji, Baimei Tan, Nannan Zhang, Tengda Ma, Yi Xu, Shihao Zhang, Yunhui Shi, Lei Guo. (2023) Effects of two mild amino acids on benzotriazole residue desorption during cobalt post-chemical mechanical polishing cleaning: Experimental and theoretical studies. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:][10.1016/j.colsurfa.2023.133052]
2.Haiying Zhai, Hongqin Liu, Baoling Shang, Xu Zou. (2023) Sarsasapogenin blocks ox-LDL-stimulated vascular smooth muscle cell proliferation, migration, and invasion through suppressing STIM1 expression. Cardiovascular Diagnosis and Therapy, [PMID:37405015][10.21037/cdt-23-111]
3.Pingping Tang, Yaobin Wang, Feiyu He. (2020) Electrochemical sensor based on super-magnetic metal–organic framework@molecularly imprinted polymer for Sarcosine detection in urine. Journal of Saudi Chemical Society, [PMID:][10.1016/j.jscs.2020.06.004]
4.Rugang Teng, Liping Wang, Mingshuo Chen, Wen Fang, Zhenguo Gao, Yinghui Chai, Pei Zhao, Ying Bao. (2020) Amino acid based pharmaceutical cocrystals and hydrate cocrystals of the chlorothiazide: Structural studies and physicochemical properties. JOURNAL OF MOLECULAR STRUCTURE, [PMID:][10.1016/j.molstruc.2020.128432]
5.Yue Yuan, Duanxiu Li, Chenguang Wang, Shaodong Chen, Minmin Kong, Zongwu Deng, Changquan Calvin Sun, Hailu Zhang. (2019) Structural Features of Sulfamethizole and Its Cocrystals: Beauty Within. CRYSTAL GROWTH & DESIGN, [PMID:][10.1021/acs.cgd.9b01060]
6.Yuan Huang, Xiaobing Huang, Liping Huang, Qicai Liu, Yun Lei, Lijuan Yang, Liying Huang. (2018) Three-phase solvent bar liquid-phase microextraction combined with high-performance liquid chromatography to determine sarcosine in human urine. JOURNAL OF SEPARATION SCIENCE, 41 (15):(3121-3128). [PMID:29878649][10.1002/jssc.201800353]
7.Yamin Liu, Xunjiang Wang, Jiaojiao Wei, Kangning Fu, Yilin Chen, Linnan Li, Zhengtao Wang, Li Yang. (2024) Comprehensive Profiling of Amino Acids and Derivatives in Biological Samples: A Robust UHPLC-MS/MS Method for Investigating Acute Lung Injury. JOURNAL OF CHROMATOGRAPHY A, [PMID:38537486][10.1016/j.chroma.2024.464816]
8.Junling Peng, Fangqian Yin, Ning Ma, Jianping Wang, Jing Liu. (2025) Detection of 13 quinolones in milk by a Pseudomonas quinolone signaling receptor-based competitive chemiluminescence assay. JOURNAL OF DAIRY SCIENCE, 109 (1):(68-82). [PMID:41412679][10.3168/jds.2025-26879]
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