L-Lysine methyl ester dihydrochloride - ≥98% , CAS No.26348-70-9

CAS: 26348-70-9 Cat. No.: L100451 Molecular Weight: 233.1 Beilstein Registry Number: 4(4)2721 EC Number: 247-625-7 PubChem CID: 117778

GRADE & PURITY ≥98%

Synonyms

HY-W009631 | Lysine, methyl ester, dihydrochloride | AC-8660 | methyl lysinate dihydrochloride | J-300191 | (S)-methyl 2,6-diaminohexanoate dihydrochloride | AM81966 | SCHEMBL1041225 | SXZCBVCQHOJXDR-ILKKLZGPSA-N | L-Lys-OMe⋅2HCl | L-Lysine methyl ester d

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Used in the synthesis of peptides containing histidine and lysine.

Specifications

Synonyms

HY-W009631 | Lysine, methyl ester, dihydrochloride | AC-8660 | methyl lysinate dihydrochloride | J-300191 | (S)-methyl 2, 6-diaminohexanoate dihydrochloride | AM81966 | SCHEMBL1041225 | SXZCBVCQHOJXDR-ILKKLZGPSA-N | L-Lys-OMe⋅2HCl | L-Lysine methyl ester d

Specifications & Purity

≥98%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488187555
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488187555
• Canonical Smiles: COC(=O)C(CCCCN)N.Cl.Cl
• IUPAC Name: methyl (2S)-2,6-diaminohexanoate;dihydrochloride
• InChIKey: SXZCBVCQHOJXDR-ILKKLZGPSA-N
• INCHI: 1S/C7H16N2O2.2ClH/c1-11-7(10)6(9)4-2-3-5-8;;/h6H,2-5,8-9H2,1H3;2*1H/t6-;;/m0../s1
• Isomeric SMILES: COC(=O)[C@H](CCCCN)N.Cl.Cl
• WGK Germany: 3
• PubChem CID: 117778
• Molecular Weight: 233.1
• Beilstein: 4(4)2721
• Reaxy-Rn: 5302183

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acid esters

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acid esters
• Alternative Parents: Fatty acid esters Methyl esters Monocarboxylic acids and derivatives Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-amino acid ester - Fatty acid ester - Fatty acyl - Methyl ester - Carboxylic acid ester - Monocarboxylic acid or derivatives - Organic nitrogen compound - Hydrochloride - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Organic oxide - Primary aliphatic amine - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Amine - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in Methanol and Water
• Sensitivity: Moisture sensitive
• Specific Rotation[α]: 17 ° (C=5, H2O)
• Melt Point(°C): 197°C
• Molecular Weight: 233.130 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 232.075 Da
• Monoisotopic Mass: 232.075 Da
• Topological Polar Surface Area: 78.300 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 117.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Hong Liang, Ao Hu, Xiaobing Chen, Rongrong Jin, Kefeng Wang, Bowen Ke, Yu Nie.  (2018)  Structure optimization of dendritic lipopeptide based gene vectors with the assistance from molecular dynamic simulation.  Journal of Materials Chemistry B,  7  (6): (915-926).  [PMID:32255097] [10.1039/C8TB02650E]

2. Wenya Feng, Juan Qiao, Dan Li, Li Qi.  (2018)  Chiral ligand exchange capillary electrochromatography with dual ligands for enantioseparation of D,L-amino acids.  TALANTA,      [PMID:30609554] [10.1016/j.talanta.2018.10.059]

3. Si Chen, Guodong Tang, Bozhen Wu, Meng Ma, Xu Wang.  (2015)  The key effect of the self-assembly mechanism of dendritic gelators: solubility parameters, generations and terminal effects.  RSC Advances,  5  (44): (35282-35290).  [PMID:] [10.1039/C4RA17339B]

4. Feng Ye, Si Chen, GuoDong Tang, Xu Wang.  (2014)  Sonication induced morphological transformation between 3D gel network and globular structure in a two-component gelation system.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2014.03.084]

5. Xiaolei Ma, Rui Cong, Xin Cui, Yiwei Tang, Jie Ren, Jinfan Hou, Boyu Liu, Jiehui Zhao, Pengwei Li, Lei Li, Heyang Zhang, Jiasheng Tu, Lei Jiang.  (2025)  Dendritic lipopeptide based transdermal siRNA delivery systems for effective non-invasive therapy in psoriasis.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40020928] [10.1016/j.jconrel.2025.113581]

6. Hong Liang, Xiaobing Chen, Rongrong Jin, Bowen Ke, Matthias Barz, Hua Ai, Yu Nie.  (2020)  Integration of Indocyanine Green Analogs as Near-Infrared Fluorescent Carrier for Precise Imaging-Guided Gene Delivery.  Small,  16  (10): (1906538).  [PMID:32022444] [10.1002/smll.201906538]