L-Theanine - 10mM in Water , CAS No.3081-61-6

CAS: 3081-61-6 Cat. No.: L423183 Molecular Weight: 174.20 EC Number: 221-379-0

GRADE & PURITY 10mM in Water

Synonyms

CCRIS 7326 | DTXSID80184817 | THEANINE, L- | L-Theanine (Ngamma-ethyl-L-glutamine) | N-Ethyl L-glutamine | NSC 21308 | Glutamine, N-ethyl-, L- | H-Glu(NHEt)-OH | N?-Ethyl-L-glutamine | MFCD00059653 | CCG-38778 | DB12444 | s3852 | SPECTRUM1505254 | UNII-80

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Synonyms

CCRIS 7326 | DTXSID80184817 | THEANINE, L- | L-Theanine (Ngamma-ethyl-L-glutamine) | N-Ethyl L-glutamine | NSC 21308 | Glutamine, N-ethyl-, L- | H-Glu(NHEt)-OH | N?-Ethyl-L-glutamine | MFCD00059653 | CCG-38778 | DB12444 | s3852 | SPECTRUM1505254 | UNII-80

Specifications & Purity

10mM in Water

Biochemical and Physiological Mechanisms

Amino acid analog of glutamine, commonly found in green tea. Binds to AMPA, kainate, NMDA and group I mGlu receptors. Displays neuroprotective and cognitive enhancing effects. Also shown to modify self-renewal properties of cancer stem cells.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

MODULATOR

Names and Identifiers

• Canonical Smiles: CCNC(=O)CCC(C(=O)O)N
• IUPAC Name: (2S)-2-amino-5-(ethylamino)-5-oxopentanoic acid
• InChIKey: DATAGRPVKZEWHA-YFKPBYRVSA-N
• INCHI: 1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
• Isomeric SMILES: CCNC(=O)CC[C@@H](C(=O)O)N
• WGK Germany: 3
• Molecular Weight: 174.20
• Reaxy-Rn: 2362121
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2362121&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Glutamine and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Glutamine and derivatives
• Alternative Parents: L-alpha-amino acids N-acyl amines Fatty acids and conjugates Secondary carboxylic acid amides Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Glutamine or derivatives - Alpha-amino acid - L-alpha-amino acid - Fatty amide - N-acyl-amine - Fatty acid - Fatty acyl - Carboxamide group - Secondary carboxylic acid amide - Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Organic oxide - Amine - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as glutamine and derivatives. These are compounds containing glutamine or a derivative thereof resulting from reaction of glutamine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: N(5)-alkyl-L-glutamine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Specific Rotation[α]: 8 ° (C=5, H2O)
• Melt Point(°C): 207°C
• Molecular Weight: 174.200 g/mol
• XLogP3: -3.600
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 174.1 Da
• Monoisotopic Mass: 174.1 Da
• Topological Polar Surface Area: 92.400 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 170.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

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