Luteolinidin chloride - ≥98% , CAS No.1154-78-5

CAS: 1154-78-5 Cat. No.: L648263 Molecular Weight: 306.70 EC Number: 601-367-5 PubChem CID: 6451196

GRADE & PURITY ≥98%

Synonyms

1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, chloride | 2-(3,4-dihydroxyphenyl)chromenylium-5,7-diol chloride | DTXSID20921728 | HY-129997 | Luteolinidol chloride | AKOS040760536 | 2-(3,4-dihydroxyphenyl)chromenylium-5,7-diol;chloride | 2-(3,4

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

Overview

Luteolinidin is a natural deoxyanthocyanidin, isolated from Sorghum bicolor Luteolinidin is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo .

Form:Solid

IC50& Target:Ki: 11 μM (CD 38)

Specifications

Synonyms

1-Benzopyrylium, 2-(3, 4-dihydroxyphenyl)-5, 7-dihydroxy-, chloride | 2-(3, 4-dihydroxyphenyl)chromenylium-5, 7-diol chloride | DTXSID20921728 | HY-129997 | Luteolinidol chloride | AKOS040760536 | 2-(3, 4-dihydroxyphenyl)chromenylium-5, 7-diol;chloride | 2-(3, 4

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Luteolinidin is a natural deoxyanthocyanidin, isolated from Sorghum bicolor. Luteolinidin is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo [

Storage

Store at 2-8°C, Protected from light, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Canonical Smiles: C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2)O)O)O)O.[Cl-]
• IUPAC Name: 2-(3,4-dihydroxyphenyl)chromenylium-5,7-diol;chloride
• InChIKey: MMAGHFOHXGFQRZ-UHFFFAOYSA-N
• INCHI: 1S/C15H10O5.ClH/c16-9-6-12(18)10-2-4-14(20-15(10)7-9)8-1-3-11(17)13(19)5-8;/h1-7H,(H3-,16,17,18,19);1H
• Isomeric SMILES: C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2)O)O)O)O.[Cl-]
• Alternate CAS: 1154-78-5
• PubChem CID: 6451196
• MeSH Entry Terms: luteolinidin
• Molecular Weight: 306.70

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Class Flavonoids
      • Subclass Hydroxyflavonoids

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Class: Flavonoids
• Subclass: Hydroxyflavonoids
• Intermediate Tree Nodes: Not available
• Direct Parent: 7-hydroxyflavonoids
• Alternative Parents: 5-hydroxyflavonoids 4'-hydroxyflavonoids 3'-hydroxyflavonoids Anthocyanidins 1-benzopyrans Catechols 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Benzene and substituted derivatives Heteroaromatic compounds Oxacyclic compounds Organooxygen compounds Organic zwitterions Organic chloride salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3'-hydroxyflavonoid - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Anthocyanidin - 1-benzopyran - Benzopyran - Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - Oxacycle - Organoheterocyclic compound - Organic oxygen compound - Organooxygen compound - Organic zwitterion - Organic salt - Organic chloride salt - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 7-hydroxyflavonoids. These are flavonoids that bear one hydroxyl group at the C-7 position of the flavonoid skeleton.
• External Descriptors: anthocyanidin chloride

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: DMSO : 50 mg/mL (163.03 mM; Need ultrasonic)
• Molecular Weight: 306.700 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 306.03 Da
• Monoisotopic Mass: 306.03 Da
• Topological Polar Surface Area: 81.900 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 336.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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