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for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Myrothecine A is a trichothecene mycotoxin found in M. roridum. Myrothecine A induces apoptosis , promotes the cytochrome c release, PARP-cleavage and phosphorylation of JNK , increases Bax and cleaved caspase-3 , -5, and -8 levels. Myrothecine A has anticancer activities and promotes the maturation of DC cells in the microenvironment. Myrothecine A inhibits proliferation of A549, MCF-7, HepG2, and SMMC-7721 cancer cells with IC 50 s of 95, 70, 60, and 25 µM, respectively.
| Canonical Smiles | CC(=O)C12CCC=CC(=O)OC3CC4C5(C3(C6(CCC(C(C5)C6O4)(C)O)COC(=O)C=C(C1O)CCO2)C)O |
|---|---|
| IUPAC Name | (1R,2S,3R,6Z,10S,14Z,19R,22R,23S,24R,26R,29R)-10-acetyl-1,22,29-trihydroxy-2,22-dimethyl-4,11,17,25-tetraoxahexacyclo[21.3.1.13,26.110,14.02,19.019,24]nonacosa-6,14-diene-5,16-dione |
| InChIKey | HGVKMRAJPCHSPC-CZFUMEEKSA-N |
| INCHI | 1S/C29H38O10/c1-16(30)28-8-5-4-6-21(31)38-19-13-20-29(35)14-18-24(39-20)27(26(19,29)3,10-9-25(18,2)34)15-36-22(32)12-17(23(28)33)7-11-37-28/h4,6,12,18-20,23-24,33-35H,5,7-11,13-15H2,1-3H3/b6-4-,17-12-/t18-,19+,20+,23+,24+,25+,26+,27+,28+,29-/m0/s1 |
| PubChem CID | 156588993 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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