N-Acetylglycyl-D-glutamic acid , CAS No.135701-69-8

CAS: 135701-69-8 Cat. No.: N287950 Molecular Weight: 246.22
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Synonyms
HMS3675I07 | J-006759 | AKOS022181024 | DTXSID20424981 | NCGC00024571-02 | SCHEMBL12648688 | SR-01000597667-1 | N-ACETYLGLYCYL-D-GLUTAMIC ACID | NCGC00024571-01 | (2R)-2-(2-ACETAMIDOACETAMIDO)PENTANEDIOIC ACID | HMS3411I07 | (R)-2-(2-Acetamidoacetamido)pe
Storage
Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
10mg
N287950-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$173.90
50mg
N287950-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$733.90
Enter a quantity for the sizes you want to add.
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
HMS3675I07 | J-006759 | AKOS022181024 | DTXSID20424981 | NCGC00024571-02 | SCHEMBL12648688 | SR-01000597667-1 | N-ACETYLGLYCYL-D-GLUTAMIC ACID | NCGC00024571-01 | (2R)-2-(2-ACETAMIDOACETAMIDO)PENTANEDIOIC ACID | HMS3411I07 | (R)-2-(2-Acetamidoacetamido)pe
Biochemical and Physiological Mechanisms
Excitatory peptide, more potent than L-glutamic acid at inducing seizures in mice.
Storage
Room temperature
Shipped In
Normal
Action Type
AGONIST
Names and Identifiers
Canonical SmilesCC(=O)NCC(=O)NC(CCC(=O)O)C(=O)O
IUPAC Name(2R)-2-[(2-acetamidoacetyl)amino]pentanedioic acid
InChIKeyCQTYJLQESPLSOP-ZCFIWIBFSA-N
INCHI1S/C9H14N2O6/c1-5(12)10-4-7(13)11-6(9(16)17)2-3-8(14)15/h6H,2-4H2,1H3,(H,10,12)(H,11,13)(H,14,15)(H,16,17)/t6-/m1/s1
Isomeric SMILES CC(=O)NCC(=O)N[C@H](CCC(=O)O)C(=O)O
Molecular Weight 246.22
Reaxy-Rn 34948603
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34948603&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Peptides
Direct ParentDipeptides
Alternative Parents Glutamic acid and derivatives  N-acyl-alpha amino acids  Alpha amino acid amides  Fatty acids and conjugates  Dicarboxylic acids and derivatives  Acetamides  Secondary carboxylic acid amides  Carboxylic acids  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Alpha-dipeptide - Glutamic acid or derivatives - N-acyl-alpha amino acid or derivatives - N-acyl-alpha-amino acid - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Fatty acid - Dicarboxylic acid or derivatives - Acetamide - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organic oxygen compound - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolvent:water, Max Conc. mg/mL: None, Max Conc. mM: 50
Molecular Weight246.220 g/mol
XLogP3-2.000
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass246.085 Da
Monoisotopic Mass246.085 Da
Topological Polar Surface Area133.000 Ų
Heavy Atom Count17
Formal Charge0
Complexity327.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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