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Semaglutide TFA - ≥99% , CAS No.S659061
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Storage
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Semaglutide TFA, a long-acting GLP-1 analogue, is a Glukagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.
Appearance:Solid
IC50& Target:GLP-1 receptor .
In Vitro:Semaglutide has two amino acid substitutions compared to human GLP-1 (Aib 8 , Arg 34 ) and is derivatized at lysine 26. The GLP-1R affinity of Semaglutide is 0.38±0.06 nM. Semaglutide is a GLP-1 analogue with 94% sequence omology to human GLP-1.
In Vivo:The plasma half-life of Semaglutide is 46h in mini-pigs following i.v. administration and semaglutide has an MRT of 63.6h after s.c. dosing to mini-pigs . Semaglutide improves 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced motor impairme
Biological Activity:Semaglutide TFA, a long-acting GLP-1 analogue, is a Glukagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.
Specifications
Specifications & Purity
≥99%
Storage
Desiccated, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
| Molecular Weight | 4227.66 |
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Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | H2O : 100 mg/mL (23.65 mM; Need ultrasonic) DMSO : 100 mg/mL (23.65 mM; ultrasonic and warming and heat to 60°C) |
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Solution Calculators
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