Tin protoporphyrin IX dichloride - ≥95% , CAS No.14325-05-4

CAS: 14325-05-4 Cat. No.: T287368 Molecular Weight: 750.25 EC Number: 853-239-5 PubChem CID: 3000478

GRADE & PURITY ≥95%

Synonyms

Tin-protoporphyrin IX | SnPPIX | Stannous protoporphyrin IX | NSC 267099 | (OC-6-13)-dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-stannate(2-), dihydrogen

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product Describtion:

Tin-protoporphyrin IX (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin-protoporphyrin IX (SnPPIX) sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model.  

Specifications

Synonyms

Tin-protoporphyrin IX | SnPPIX | Stannous protoporphyrin IX | NSC 267099 | (OC-6-13)-dichloro[7, 12-diethenyl-3, 8, 13, 17-tetramethyl-21H, 23H-porphine-2, 18-dipropanoato(4-)-κN21, κN22, κN23, κN24]-stannate(2-), dihydrogen

Specifications & Purity

≥95%

Biochemical and Physiological Mechanisms

A potent inhibitor of heme oxygenase. Prevents hyperbilirubinemia in neonates.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Canonical Smiles: C=CC1=C(/C=C3\\N=C(/C=C(N5[Sn](Cl)6Cl)/C(C)=C(CCC(O)=O)/C5=C4)C(C=C)=C3C)N6C(/C=C2/C(C)=C(CCC(O)=O)C/4=N2)=C1C
• InChIKey: ZUQBMBXSEXXKTO-UHFFFAOYSA-L
• Isomeric SMILES: CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Sn+4]
• PubChem CID: 3000478
• Molecular Weight: 750.25

Chemical and Physical Properties

• Solubility: Solvent:1eq. NaOH, Max Conc. mg/mL: 18.76, Max Conc. mM: 25; Solvent:DMSO, Max Conc. mg/mL: 3.75, Max Conc. mM: 5
• Sensitivity: Moisture sensitive