Ubiquitination-IN-1 - ≥98% , CAS No.1819330-15-8

CAS: 1819330-15-8 Cat. No.: U651000 Molecular Weight: 429.41 EC Number: 995-977-1

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction ( IC 50 =0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 has the potential for treatment disease by blocking the degradation of tumor suppressors.

In Vitro

Ubiquitination-IN-1 inhibits A549 and HT1080 cells with IC 50 s of 0.91 and 0.4 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction ( IC 50 =0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 has the potential for treatment disease by blocking the degradati

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: O=S(C1=CC=CC(C(F)(F)F)=C1)(NC2=C3N=CC=CC3=C(C4=CC=CN=C4)C=C2)=O
• Molecular Weight: 429.41

Chemical and Physical Properties

• Solubility: DMSO : 83.33 mg/mL (194.06 mM; ultrasonic and warming and heat to 60°C)