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· · COA & SDS available for every product · Same-day shipping on in-stock items Verlukast - Moligand™, ≥98% , Antagonist of CysLT 1 receptor;Inhibitor of OATP2B1, CAS No.120443-16-5, Antagonist of CysLT 1 receptor;Inhibitor of OATP2B1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
3-(((.ALPHA.R)-M-((E)-2-(7-CHLORO-2-QUINOLYL)VINYL)-.ALPHA.-((2-(DIMETHYLCARBAMOYL)ETHYL)THIO)BENZYL)THIO)PROPIONIC ACID | R-(-)-MK 571 | 3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid |
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Product Application:
A receptor antagonist for the treatment of respiratory diseases.
Specifications Synonyms
3-(((.ALPHA.R)-M-((E)-2-(7-CHLORO-2-QUINOLYL)VINYL)-.ALPHA.-((2-(DIMETHYLCARBAMOYL)ETHYL)THIO)BENZYL)THIO)PROPIONIC ACID | R-(-)-MK 571 | 3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid |
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Verlukast(MK-679; L 668019) is a receptor antagonist for the treatment of respiratory diseases.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST, INHIBITOR
Mechanism of action
Antagonist of CysLT 1 receptor;Inhibitor of OATP2B1
Names and Identifiers Pubchem Sid 504764271 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504764271 Canonical Smiles CN(C)C(=O)CCSC(C1=CC=CC(=C1)C=CC2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)O IUPAC Name 3-[(R)-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoic acid InChIKey AXUZQJFHDNNPFG-LHAVAQOQSA-N INCHI 1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+/t26-/m1/s1 Isomeric SMILES CN(C)C(=O)CCS[C@@H](C1=CC=CC(=C1)/C=C/C2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)O Molecular Weight 515.09 Reaxy-Rn 24674053 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24674053&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Quinolines and derivatives Subclass Haloquinolines Intermediate Tree Nodes Not available Direct Parent Chloroquinolines Alternative Parents Styrenes Aryl chlorides Pyridines and derivatives Tertiary carboxylic acid amides Dithioacetals Heteroaromatic compounds Sulfenyl compounds Azacyclic compounds Carboxylic acids Dialkylthioethers Monocarboxylic acids and derivatives Organonitrogen compounds Organochlorides Hydrocarbon derivatives Carbonyl compounds Organic oxides Molecular Framework Aromatic heteropolycyclic compounds Substituents Chloroquinoline - Styrene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Pyridine - Benzenoid - Heteroaromatic compound - Thioacetal - Tertiary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Carboxylic acid - Azacycle - Monocarboxylic acid or derivatives - Dialkylthioether - Sulfenyl compound - Thioether - Organohalogen compound - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Organochloride - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Carbonyl group - Hydrocarbon derivative - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as chloroquinolines. These are compounds containing a quinoline moiety, which carries one or more chlorine atoms. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), THF (Slightly, Sonicate) Melt Point(°C) 57-62°C Molecular Weight 515.100 g/mol XLogP3 5.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 11 Exact Mass 514.115 Da Monoisotopic Mass 514.115 Da Topological Polar Surface Area 121.000 Ų Heavy Atom Count 34 Formal Charge 0 Complexity 693.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 1
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