Vindoline - ≥98%(HPLC) , CAS No.2182-14-1

CAS: 2182-14-1 Cat. No.: V101706 Molecular Weight: 456.53 EC Number: 218-558-0 PubChem CID: 260535

3 Citations COA

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Vindoline - ≥98%(HPLC) CAS No(2182-14-1) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY ≥98%(HPLC)

Synonyms

CHEBI:16380 | NSC-628056 | MFCD27991347 | methyl 4beta-acetyloxy-3beta-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2beta,5alpha,12beta,19alpha-aspidospermidine-3alpha-carboxylate | Q15427936 | NSC823866 | NSC-823866 | SMP2_000150 | SR-05000002168-2 | 571PJ1

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Citations of This Product References Solution Calculators Reviews

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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms

CHEBI:16380 | NSC-628056 | MFCD27991347 | methyl 4beta-acetyloxy-3beta-hydroxy-16-methoxy-1-methyl-6, 7-didehydro-2beta, 5alpha, 12beta, 19alpha-aspidospermidine-3alpha-carboxylate | Q15427936 | NSC823866 | NSC-823866 | SMP2_000150 | SR-05000002168-2 | 571PJ1

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Weak tubulin polymerization inhibitor. H + /K + ATPase inhibitor (IC 50 = 846 μM). Precursor molecule of vinblastine and vincristine . Weakly affects bipolar mitotic spindle formation. Active in vivo.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%(HPLC)

Names and Identifiers

Pubchem Sid	504758188
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504758188
Canonical Smiles	CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C
IUPAC Name	methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
InChIKey	CXBGOBGJHGGWIE-ACSXSLCXSA-N
INCHI	1S/C25H32N2O6/c1-6-23-10-7-12-27-13-11-24(19(23)27)17-9-8-16(31-4)14-18(17)26(3)20(24)25(30,22(29)32-5)21(23)33-15(2)28/h7-10,14,19-21,30H,6,11-13H2,1-5H3/t19-,20+,21+,23+,24+,25-/m0/s1
Isomeric SMILES	CC[C@@]12C=CCN3[C@@H]1[C@]4(CC3)[C@H]([C@]([C@@H]2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C
WGK Germany	3
RTECS	CJ0120000
PubChem CID	260535
Molecular Weight	456.53

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Alkaloids and derivatives
  - Class Plumeran-type alkaloids

Kingdom	Organic compounds
Superclass	Alkaloids and derivatives
Class	Plumeran-type alkaloids
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Plumeran-type alkaloids
Alternative Parents	Carbazoles Anisoles Dialkylarylamines Alkyl aryl ethers Aralkylamines N-alkylpyrrolidines Dicarboxylic acids and derivatives Tertiary alcohols Methyl esters Amino acids and derivatives Trialkylamines Cyclic alcohols and derivatives Azacyclic compounds Carbonyl compounds Organic oxides Organopnictogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Plumeran-type alkaloid - Carbazole - Indole or derivatives - Anisole - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Alkyl aryl ether - Aralkylamine - N-alkylpyrrolidine - Benzenoid - Dicarboxylic acid or derivatives - Methyl ester - Cyclic alcohol - Tertiary alcohol - Pyrrolidine - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Ether - Organic nitrogen compound - Hydrocarbon derivative - Alcohol - Carbonyl group - Organic oxide - Organopnictogen compound - Amine - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as plumeran-type alkaloids. These are alkaloids with a structure based on the plumeran skeleton. Plumeran is a pentacyclic compound that consists of a pyrrolidine ring shed to the quinoline moiety of pyrido[3,2-c]carbazole ring system.
External Descriptors	Indole alkaloids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

A498 (42825 Activities)

Lot Number	Certificate Type	Date	Item
F2205160	Certificate of Analysis	Mar 13, 2026	V101706
F2205161	Certificate of Analysis	Mar 13, 2026	V101706
I1523063	Certificate of Analysis	Jun 05, 2023	V101706

Molecular Weight	456.500 g/mol
XLogP3	1.300
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Exact Mass	456.226 Da
Monoisotopic Mass	456.226 Da
Topological Polar Surface Area	88.500 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	864.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1