Inhibits NFκB; blocks androgen receptor (AR) expression
Andrographolide, a bioactive diterpene lactone, is the main constituent of Andrographis paniculata, a plant used in traditional medicines. It is known to have different biological activities such as anti-inflammatory, anti-malarial, anti-cancer and hepatoprotective activity. It also shows potent anti-viral effect against dengue virus
| CAS | 5508-58-7 |
|---|---|
| Synonyms | ANDROGRAPHOLIDE [MI] | DTXCID1025980 | Q-100624 | DTXSID3045980 | (S,E)-4-Hydroxy-3-(2-((1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)ethylidene)dihydrofuran-2 | BRD-K89282837-001-01-0 | NSC-115849 | Q475 |
| Specifications & Purity | Moligand™, ≥98% |
| Storage | Room temperature |
| Shipped In | Normal |
| Product Description | Andrographolide, a bioactive diterpene lactone, is the main constituent of Andrographis paniculata, a plant used in traditional medicines. It is known to have different biological activities such as anti-inflammatory, anti-malarial, anti-cancer and hepatoprotective activity. It also shows potent anti-viral effect against dengue virus |
| Pubchem Sid | 488195335 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488195335 |
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 35.05, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 3.5, Max Conc. mM: 10 |
| Mdl Number | MFCD07778082 |
| EC Number | 226-852-5 |
| PubChem CID | 5318517 |
| Molecular Formula | C20H30O5 |
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