Cyanine3 amine hydrochloride - BioReagent, for Fluorescence analysis, for Microscopy, ≥95%(HPLC), Soluble in organic solvents (DMF, DMSO, Methanol) , CAS No.2247688-56-6

CAS: 2247688-56-6 Cat. No.: C595883 Formula: C₃₆H₅₂Cl₂N₄O Molecular Weight: 627.73 PubChem CID: 91757861

GRADE & PURITY BioReagent, for Fluorescence analysis, for Microscopy, ≥95%(HPLC), Soluble in organic solvents (DMF, DMSO, Methanol)

Synonyms

Cy3 Amine hydrochloride | Cy3 amine | Cy3‑NH₂ hydrochloride | Cy3‑Amine hydrochloride | Cyanine3 amine hydrochloride | Cyanine3 amine | Cyanine 3 Amine | Cyanine3 amine HCl | Cy3-Amine chloride hydrochloride | 1-(6-((6-Aminohexyl)amino)-6-oxohexyl)-3,3-di

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

DNA labeling and detection, Fluorescence Analysis, Protein/Antibody Labeling

Overview

Extinction Coefficient Excitation Maximum: 150000;Fluorescence Quantum Yield: 0.31

Cy3 amine is a functionalized cyanine dye containing a free amine group, which can be conjugated with reactive groups such as NHS esters, carboxy groups, epoxides, etc.

Specifications

Synonyms

Cy3 Amine hydrochloride | Cy3 amine | Cy3‑NH₂ hydrochloride | Cy3‑Amine hydrochloride | Cyanine3 amine hydrochloride | Cyanine3 amine | Cyanine 3 Amine | Cyanine3 amine HCl | Cy3-Amine chloride hydrochloride | 1-(6-((6-Aminohexyl)amino)-6-oxohexyl)-3,3-di

Specifications & Purity

BioReagent, for Fluorescence analysis, for Microscopy, ≥95%(HPLC), Soluble in organic solvents (DMF, DMSO, Methanol)

Stability And Storage

Store at -20℃ long term (24 months). Store in the dark. Desiccated.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

BioReagent, for Fluorescence analysis, for Microscopy

Purity

≥95%(HPLC)

Names and Identifiers

• Canonical Smiles: CC1(C2=CC=CC=C2[N+](=C1C=CC=C3C(C4=CC=CC=C4N3CCCCCC(=O)NCCCCCC[NH3+])(C)C)C)C.[Cl-].[Cl-]
• IUPAC Name: 6-[6-[(2E)-3,3-dimethyl-2-[(E)-3-(1,3,3-trimethylindol-1-ium-2-yl)prop-2-enylidene]indol-1-yl]hexanoylamino]hexylazanium;dichloride
• InChIKey: VYQVCEXMTWTAMW-UHFFFAOYSA-N
• INCHI: 1S/C36H50N4O.2ClH/c1-35(2)28-18-10-12-20-30(28)39(5)32(35)22-17-23-33-36(3,4)29-19-11-13-21-31(29)40(33)27-16-8-9-24-34(41)38-26-15-7-6-14-25-37;;/h10-13,17-23H,6-9,14-16,24-27,37H2,1-5H3;2*1H
• Isomeric SMILES: CC1(C2=CC=CC=C2[N+](=C1/C=C/C=C/3\C(C4=CC=CC=C4N3CCCCCC(=O)NCCCCCC[NH3+])(C)C)C)C.[Cl-].[Cl-]
• PubChem CID: 91757861
• Molecular Weight: 627.73

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Indoles and derivatives
      • Subclass Indoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Indoles and derivatives
• Subclass: Indoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 3-alkylindoles
• Alternative Parents: Tertiary alkylarylamines N-acyl amines Benzenoids Quaternary ammonium salts Secondary carboxylic acid amides Amino acids and derivatives Propargyl-type 1,3-dipolar organic compounds Enamines Azacyclic compounds Organic oxides Organic chloride salts Monoalkylamines Hydrocarbon derivatives Carbonyl compounds Organic cations
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3-alkylindole - Tertiary aliphatic/aromatic amine - Fatty amide - N-acyl-amine - Benzenoid - Fatty acyl - Quaternary ammonium salt - Carboxamide group - Amino acid or derivatives - Tertiary amine - Secondary carboxylic acid amide - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboxylic acid derivative - Enamine - Organic oxide - Hydrocarbon derivative - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Primary aliphatic amine - Amine - Organic salt - Organic chloride salt - Carbonyl group - Organic cation - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solubility in Water, DMSO, DMF, DCM

References

1. Kairuo Wang, Qian Chen, Li Ding, Yefei Zhu, Xinyue Wang, Mengting Zhou, Meiqi Chang, Manman Pei, Yuanyuan Zhang, Yang Zhang, Yu Chen, Huanlong Qin.  (2023)  Mucoadhesive probiotic-based oral microcarriers with prolonged intestinal retention for inflammatory bowel disease therapy.  Nano Today,      [PMID:] [10.1016/j.nantod.2023.101876]

2. Shiyuan Liang, Liyuan Chen, Cong Liu, Bowen Guo, Yijie Fan, Zhou Li, Yan Liu, Dan Luo.  (2024)  Ultrathin ZIF-8 Coating-Reinforced Enzyme Nanoformulation Avoids Lysosomal Degradation for Senile Osteoporosis Therapy.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202410931]