Rat Adrenomedullin, Acetate, Agonist of AM 1 receptor;Agonist of AM 2 receptor;Agonist of AMY 1 receptor;Agonist of AMY 2 receptor;Agonist of AMY 3 receptor;Agonist of CGRP receptor;Agonist of CT receptor, CAS No.159964-38-2 (free base), Agonist of AM 1 receptor;Agonist of AM 2 receptor;Agonist of AMY 1 receptor;Agonist of AMY 2 receptor;Agonist of AMY 3 receptor;Agonist of CGRP receptor;Agonist of CT receptor

CAS: 159964-38-2 (free base) Cat. No.: rp173387
AVAILABLE TO ORDER
GRADE & PURITY BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. ≥95%(HPLC)
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
500μg
rp173387-500μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$299.90
5×500μg
rp173387-5×500μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$879.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

BioReagent,≥95%(HPLC) BioReagent for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Adrenomedullin (1-50), rat acetate is a 1–50 amino acid fragment of rat-derived adrenomedullin polypeptide in acetate salt form. As a multifunctional regulatory peptide, it is mainly involved in physiological processes such as cardiovascular homeostasis, inflammatory response and cell proliferation, and can be applied to physiological and pharmacological mechanism researches related to rats. 
Molecular Formula: C₂₅₆H₄₀₈N₇₈O₇₁S₂ (free base)
Molecular Weight: 5729.49 (free base) 
Sequence: Ac-Tyr-Arg-Gln-Ser-Met-Asn-Gln-Gly-Ser-Arg-Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH₂ (Disulfide bond formed between Cys14–Cys19; C-terminal amidated, N-terminal acetylated)

Specifications

Product Name
Rat Adrenomedullin, Acetate, Agonist of AM 1 receptor;Agonist of AM 2 receptor;Agonist of AMY 1 receptor;Agonist of AMY 2 receptor;Agonist of AMY 3 receptor;Agonist of CGRP receptor;Agonist of CT receptor, CAS No.159964-38-2 (free base)
Synonyms
AM | ADM (rat) acetate | Rat Adrenomedullin acetate | Adrenomedullin (1-50), rat acetate
Grade
BioReagent
Specifications & Purity
BioReagent, ≥95%(HPLC)
Sequence
YRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGY-NH₂
Predicted molecular weight
5729.49 (free base)
Action Type
AGONIST
Mechanism of action
Agonist of AM 1 receptor;Agonist of AM 2 receptor;Agonist of AMY 1 receptor;Agonist of AMY 2 receptor;Agonist of AMY 3 receptor;Agonist of CGRP receptor;Agonist of CT receptor
CAS
159964-38-2 (free base)
Molecule Type
Peptide
Storage and Shipping
Storage
Protected from light,Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ long term (24 months). Store in the dark. Desiccated.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
RAMP2 Tclin Receptor activity-modifying protein 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RAMP1 Tclin Receptor activity-modifying protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RAMP3 Tclin Receptor activity-modifying protein 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CALCR Tclin Calcitonin receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CALCRL Tclin Calcitonin gene-related peptide type 1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
ZJ26F0535208Certificate of AnalysisMay 09, 2026 rp173387
Genetic information
Alternate NamesAM | ADM (rat) acetate | Rat Adrenomedullin acetate | Adrenomedullin (1-50), rat acetate
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more
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