c-di-AMP disodium - Moligand™, ≥98% , CAS No.2734909-87-4

CAS: 2734909-87-4 Cat. No.: C651421 Molecular Weight: 702.38

GRADE & PURITY Moligand™, ≥98%

Synonyms

Cyclic-di-AMP disodium | Cyclic diadenylate disodium

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses

Specifications

Synonyms

Cyclic-di-AMP disodium | Cyclic diadenylate disodium

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial s

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥98%

Names and Identifiers

• Canonical Smiles: O[C@H]([C@@](OP(OC[C@](O[C@@H](N1C2=NC=NC(N)=C2N=C1)[C@@H]3O)([H])[C@@]3([H])O4)(O[Na])=O)([H])[C@](COP4(O[Na])=O)([H])O5)[C@@H]5N6C7=NC=NC(N)=C7N=C6
• Alternate CAS: 54447-84-6
• Molecular Weight: 702.38

Chemical and Physical Properties

• Solubility: DMSO : 270 mg/mL (384.41 mM; Need ultrasonic) H2O : ≥ 50 mg/mL (71.19 mM)
• Sensitivity: Light sensitive