CD8 alpha Mouse mAb (Biotin) - Primärer Antikörper, specific to CD8 alpha

Cat. No.: Ab190484

QUALITÄT & REINHEIT ExactAb™, Validated, 0.5 mg/mL

Application

Flow Cytometry

Host species

Maus

Reactive species

Mensch

Isotype

Mouse IgG2a

Clone Number

OKT-8

Conjugation

Biotin

Übersicht

Mouse anti Human CD8 alpha Antibody, Monoclonal (OKT-8), could be used for Flow, in vivo CD8+ T cell depletion in humanized mice and so on.

Spezifikationen

Product Name

CD8 alpha Mouse mAb (Biotin) - Primärer Antikörper, specific to CD8 alpha

Synonyme

CD8 | Leu2 | IMD116 | CD8alpha | CD_antigen: CD8a | CD8 antigen, alpha polypeptide (p32) | Biotin Anti-Human CD8a Antibody[OKT-8] | Biotin Anti-Human CD8a (OKT8) | Biotin Mouse Anti-Human CD8 | CD8a Monoclonal Antibody (OKT-8), Biotin | Biotin anti-human

Spezifikationen & Reinheit

ExactAb™, Validated, 0.5 mg/mL

Biochemische und physiologische Mechanismen

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

Wirtsspezies

Maus

Spezifität

CD8 alpha

Immunogen

Human CD8α

Positive Kontrolle

Flow: Human peripheral blood lymphocytes

Konjugation

Biotin

Note

ExactAb™, Validated

Lichterketten-Typ

kappa

Verfahren zur Reinigung

Protein G purified

Konzentration

0.5 mg/mL

Product Line

Biologische Produkte

Lagerung und Versand

Storage

Store at 2-8°C,Protected from light,Do not freeze

Verschickt in

Wet ice,Do not freeze

Stabilität und Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Bilder

Flow Cytometry: CD8 alpha Mouse mAb (Biotin) (Ab190484)

CD8 alpha Mouse mAb (Biotin) (Ab190484) - Flow Cytometry
Flow cytometry analysis of CD8 alpha expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with CD8 alpha Mouse mAb (Biotin) (Ab190484) at 0.3μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Left panel - Mouse IgG (Biotin) (Ab180306).

Flow Cytometry: CD8 alpha Mouse mAb (Biotin) (Ab190484)

CD8 alpha Mouse mAb (Biotin) (Ab190484) - Flow Cytometry
Flow cytometry analysis of CD8 alpha expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with CD8 alpha Mouse mAb (Biotin) (Ab190484) at 0.3μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Blue - Mouse IgG (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

Anwendung

Anwendung

Dilution info

Flow Cytometry

≤0.3 μg/test, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume

Zugehörige Ziele (menschlich)

CD8A Tbio T-cell surface glycoprotein CD8 alpha chain (0 Activities)

Discover Target: CD8A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)