Name: Cholesterol - AR, ≥95%(HPLC) , CAS No.57-88-5
Brand: Aladdin Scientific
SKU: C104028
Availability: InStock

Übersicht Spezifikationen Namen und Kennungen Dokumentation Erweiterte Daten Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften FAQs und Artikel Citations of This Product Lösungsrechner Bewertungen

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Warum diese Qualität

AR, ≥95%(HPLC) AR für empfindliche chromatographische und analytische Workflows, die minimale Basislinieninterferenzen erfordern.

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Lagerung & Versand

Protected from light,Store at -20°C,Argon charged Versand Ice chest + Ice pads. Genaue Spezifikationen finden Sie im chargenspezifischen COA.

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Qualitätsdokumente

SDS, COA, Datenblatt und Spezifikationsblatt stehen zum Download bereit. Chargenspezifische COA über Chargennummernsuche abrufbar.

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Literaturbeleg

In 581 peer-reviewten Publikationen zu Chromatographie, organischer Synthese und Kreuzkupplungsreaktionen zitiert.

Übersicht

A structural component of cell membranes

Spezifikationen

Synonyme

Spezifikationen & Reinheit

AR, ≥95%(HPLC)

Biochemische und physiologische Mechanismen

Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the fun

Storage

Protected from light,Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥95%(HPLC)

Namen und Kennungen

Pubchem Sid

488179983

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488179983

Kanonisches Lächeln

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

IUPAC Name

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

InChIKey

HVYWMOMLDIMFJA-DPAQBDIFSA-N

INCHI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

Isomere SMILES

C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C

WGK Deutschland

RTECS

FZ8400000

Molekulargewicht

386.65

Beilstein

1915888

Reaxy-Rn

2060565

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2060565&ln=

Dokumentation

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Umfassendes Dokument zu Gefahren, Handhabung, Lagerung und Einhaltung regulatorischer Vorschriften.

<<<<<<< HEAD SDS herunterladen → ======= SDS herunterladen → >>>>>>> release248-p3

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Vollständige Qualitätsmerkmale und Akzeptanzkriterien für diese Qualität.

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Erweiterte Daten

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Klasse Steroids and steroid derivatives
    - Subclass Cholestane steroids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Klasse	Steroids and steroid derivatives
Subclass	Cholestane steroids
Intermediate Tree Nodes	Not available
Direct Parent	Cholesterols and derivatives
Alternative Parents	3-beta-hydroxysteroids 3-beta-hydroxy delta-5-steroids Delta-5-steroids Secondary alcohols Cyclic alcohols and derivatives Hydrocarbon derivatives
Molecular Framework	Aliphatic homopolycyclic compounds
Substituents	Cholesterol-skeleton - Cholesterol - 3-beta-hydroxysteroid - 3-beta-hydroxy-delta-5-steroid - Hydroxysteroid - 3-hydroxysteroid - 3-hydroxy-delta-5-steroid - Delta-5-steroid - Cyclic alcohol - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homopolycyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as cholesterols and derivatives. These are compounds containing a 3-hydroxylated cholestane core.
External Descriptors	Cholesterol and derivatives
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

Zugehörige Ziele (menschlich)

CYP46A1 Tchem Cholesterol 24-hydroxylase (2 Activities)

Discover Target: CYP46A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma (1 Activities)

Discover Target: RORC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP11A1 Tclin Cytochrome P450 11A1 (1 Activities)

Discover Target: CYP11A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLA1 Tclin DNA polymerase alpha subunit (225 Activities)

Discover Target: POLA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NPC1L1 Tclin Niemann-Pick C1-like protein 1 (346 Activities)

Discover Target: NPC1L1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLB Tchem DNA polymerase beta (23632 Activities)

Discover Target: POLB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR1H3 Tchem LXR-alpha (2891 Activities)

Discover Target: NR1H3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCRF-CEM (65223 Activities)

Lot Number	Certificate Type	Datum	Artikel
D2621283	Certificate of Analysis	Mar 13, 2026	C104028
D2621258	Certificate of Analysis	Mar 13, 2026	C104028
D2621256	Certificate of Analysis	Mar 13, 2026	C104028
D2621257	Certificate of Analysis	Mar 13, 2026	C104028
L2511305	Certificate of Analysis	Nov 29, 2025	C104028
L2511304	Certificate of Analysis	Nov 29, 2025	C104028
L2511297	Certificate of Analysis	Nov 29, 2025	C104028
L2511281	Certificate of Analysis	Nov 29, 2025	C104028
F2520316	Certificate of Analysis	Mar 21, 2025	C104028
I2509059	Certificate of Analysis	Mar 21, 2025	C104028
F2520315	Certificate of Analysis	Mar 21, 2025	C104028
F2520314	Certificate of Analysis	Mar 21, 2025	C104028
F2520245	Certificate of Analysis	Mar 21, 2025	C104028
B2518250	Certificate of Analysis	Dec 17, 2024	C104028
B2518251	Certificate of Analysis	Dec 17, 2024	C104028
B2527701	Certificate of Analysis	Dec 17, 2024	C104028
B2518236	Certificate of Analysis	Dec 17, 2024	C104028
I2429102	Certificate of Analysis	Sep 18, 2024	C104028
I2429149	Certificate of Analysis	Sep 18, 2024	C104028
I2429148	Certificate of Analysis	Sep 18, 2024	C104028
H2020293	Certificate of Analysis	Jun 04, 2024	C104028
L2318351	Certificate of Analysis	Dec 06, 2023	C104028
L2318352	Certificate of Analysis	Dec 06, 2023	C104028
L2318353	Certificate of Analysis	Dec 06, 2023	C104028
L2318354	Certificate of Analysis	Dec 06, 2023	C104028
D2303563	Certificate of Analysis	Dec 08, 2022	C104028
D2303558	Certificate of Analysis	Dec 08, 2022	C104028
D2303557	Certificate of Analysis	Dec 08, 2022	C104028
D2303556	Certificate of Analysis	Dec 08, 2022	C104028
D2303559	Certificate of Analysis	Dec 08, 2022	C104028
D2303560	Certificate of Analysis	Dec 08, 2022	C104028
D2303562	Certificate of Analysis	Dec 08, 2022	C104028
G2226252	Certificate of Analysis	Jun 08, 2022	C104028
G2226253	Certificate of Analysis	Jun 08, 2022	C104028
G2226254	Certificate of Analysis	Jun 08, 2022	C104028
G2226223	Certificate of Analysis	Jun 08, 2022	C104028

Löslichkeit	Soluble in hot alcohol, chloroform, pyridine, benzene, fats , oils, acetone, dioxane, ethyl acetate, petroleum ether, and ether. Insoluble in water.
Empfindlichkeit	heat sensitive;air sensitive;Light sensitive;Moisture sensitive
Spezifische Drehung [α]	-37 ° (C=2, Dioxane)
Siedepunkt (°C)	360°C
Schmelzpunkt (°C)	148.5°C
Molekulargewicht	386.700 g/mol
XLogP3	8.700
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	5
Exact Mass	386.355 Da
Monoisotopic Mass	386.355 Da
Topological Polar Surface Area	20.200 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	591.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	8
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Cholesterol - AR, ≥95%(HPLC) , CAS No.57-88-5

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Literaturbeleg

Übersicht

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Dokumentation

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