Carrier Free,ExactAb™,Low Endotoxin,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE&SEC-HPLC),See COA Azide Free,Carrier Free,ExactAb™,Low Endotoxin,PBS Only,Validated für empfindliche chromatographische und analytische Workflows, die minimale Basislinieninterferenzen erfordern.

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Lagerung & Versand

Store at -80°C,Avoid repeated freezing and thawing Versand Dry ice packs + Cold packs. Genaue Spezifikationen finden Sie im chargenspezifischen COA.

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Qualitätsdokumente

SDS, COA, Datenblatt und Spezifikationsblatt stehen zum Download bereit. Chargenspezifische COA über Chargennummernsuche abrufbar.

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Literaturbeleg

In 0 peer-reviewten Publikationen zu Chromatographie, organischer Synthese und Kreuzkupplungsreaktionen zitiert.

Übersicht

Mouse anti Human CXCR4/CD184 Antibody, Monoclonal (12G5), could be used for Block, Flow, ICC, IF, IHC, Neutralization, WB and so on.
Application
Block: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration.
ICC/IF: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
Neutralization: Use at an assay dependent concentration.
WB: Use at an assay dependent concentration.
Protein Function
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.

Spezifikationen

Product Name

CXCR4/CD184 Mouse mAb - Primärer Antikörper, specific to CXCR4/CD184, Mouse IgG2a

Synonyme

Spezifikationen & Reinheit

Carrier Free,ExactAb™,Low Endotoxin,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE&SEC-HPLC),See COA

Wirtsspezies

Maus

Spezifität

CXCR4/CD184

Konjugation

Unconjugated

Note

Azide Free, Carrier Free, ExactAb™, Low Endotoxin, PBS Only, Validated

Isotyp

Mouse IgG2a

Lichterketten-Typ

kappa

Verfahren zur Reinigung

Protein A/G purified

Konzentration

See COA

Product Line

Biologische Produkte

Lagerung und Versand

Form

Liquid

Storage

Store at -80°C,Avoid repeated freezing and thawing

Verschickt in

Dry ice packs + Cold packs

Stabilität und Lagerung

Store at 4°C short term (1-2 weeks). Store at -80°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

Flow Cytometry: CXCR4/CD184 Mouse mAb (Ab098344)

CXCR4/CD184 Mouse mAb (Ab098344) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CXCR4/CD184 with CXCR4/CD184 Mouse mAb (Ab098344) conjugated with biotin (right panel) at 1.0 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: CXCR4/CD184 Mouse mAb (Ab098344)

CXCR4/CD184 Mouse mAb (Ab098344) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CXCR4/CD184 (red) with CXCR4/CD184 Mouse mAb (Ab098344) conjugated with biotin at 1.0 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

SEC: CXCR4/CD184 Mouse mAb (Ab098344)

CXCR4/CD184 Mouse mAb (Ab098344) - SEC
The purity of CXCR4/CD184 Mouse mAb (Ab098344) is more than 95% verified by HPLC.

Anwendung

Dilution info