GRADE & PURITY Standard for GC, ≥99.5%(GC)

Synonyms

diethyleneglycol monoethyl-d5 ether | 3,6-Dioxa-1-oktanol [Czech] | Ethanol, 2,2'-oxybis-, monoethyl ether | Ethylene diglycol monoethyl ether | 1-Hydroxy-3,6-dioxaoctane | Karbitol | PM 1799 | SCHEMBL16399 | DIETHYLENE GLYCOL MONOETHYL ESTER | DIETHYLENE

Storage

Room temperature,Desiccated

Shipped In

Normal

Overview

Usually used as solvent for the polymer electrospinning.

Specifications

Synonyms

diethyleneglycol monoethyl-d5 ether | 3, 6-Dioxa-1-oktanol [Czech] | Ethanol, 2, 2'-oxybis-, monoethyl ether | Ethylene diglycol monoethyl ether | 1-Hydroxy-3, 6-dioxaoctane | Karbitol | PM 1799 | SCHEMBL16399 | DIETHYLENE GLYCOL MONOETHYL ESTER | DIETHYLENE

Specifications & Purity

Standard for GC, ≥99.5%(GC)

Storage

Room temperature, Desiccated

Shipped In

Normal

Grade

Standard for GC

Purity

≥99.5%(GC)

Names and Identifiers

• Canonical Smiles: CCOCCOCCO
• IUPAC Name: 2-(2-ethoxyethoxy)ethanol
• InChIKey: XXJWXESWEXIICW-UHFFFAOYSA-N
• INCHI: 1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3
• Isomeric SMILES: CCOCCOCCO
• WGK Germany: 1
• RTECS: KK8750000
• Molecular Weight: 134.17
• Beilstein: 1736441
• Reaxy-Rn: 1736441
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1736441&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Ethers

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Ethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Dialkyl ethers
• Alternative Parents: Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Dialkyl ether - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as dialkyl ethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups.
• External Descriptors: primary alcohol - diether - hydroxypolyether

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: It is miscible with acetone, benzene, chloroform, ethanol, and ether.
• Sensitivity: Hygroscopic
• Refractive Index: 1.4273
• Flash Point(°C): (open cup)96℃
• Boil Point(°C): 196°C
• Melt Point(°C): -76°C
• Molecular Weight: 134.170 g/mol
• XLogP3: -0.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 134.094 Da
• Monoisotopic Mass: 134.094 Da
• Topological Polar Surface Area: 38.700 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 47.600
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Jianxia Dong, Shu Wang, Jiamin Mao, Zhidan Wang, Shiying Zhao, Qiao Ren, Jialing Kang, Jing Ye, Xiaohong Xu, Yujin Zhu, Quan Zhang.  (2023)  Preparation of Dihydromyricetin-Loaded Self-Emulsifying Drug Delivery System and Its Anti-Alcoholism Effect.  Pharmaceutics,  15  (9): (2296).  [PMID:37765265] [10.3390/pharmaceutics15092296]

2. Tong Le, Zhou ZeYang, Wang Gang, Wu Chao.  (2022)  A self-microemulsion enhances oral absorption of docetaxel by inhibiting P-glycoprotein and CYP metabolism.  Drug Delivery and Translational Research,  13  (4): (983-993).  [PMID:36515864] [10.1007/s13346-022-01255-x]

3. Jinlin Xu, Yintung Lam, Hongqi Liu, Jinbin Luo, Benjamin Tawiah, Guoshuai Liu, Hao Jia.  (2022)  Highly stable and low-temperature-tolerant zinc ion storage enabled by carbitol electrolyte additive engineering.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:36368213] [10.1016/j.jcis.2022.10.127]

4. Dan Zhao, Dong Li, Fenli Quan, Yuhao Zhou, Zhen Zhang, Xuesi Chen, Chaoliang He.  (2021)  Rapidly Thermoreversible and Biodegradable Polypeptide Hydrogels with Sol–Gel–Sol Transition Dependent on Subtle Manipulation of Side Groups.  BIOMACROMOLECULES,      [PMID:34297548] [10.1021/acs.biomac.1c00583]

5. Meesam Ali, Usman Farooq, Shuguang Lyu, Yong Sun, Ming Li, Ayyaz Ahmad, Ali Shan, Zain Abbas.  (2020)  Synthesis of controlled release calcium peroxide nanoparticles (CR-nCPs): Characterizations, H2O2 liberate performances and pollutant degradation efficiency.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2020.116729]

6. Bin Jiang, Zhaohe Huang, Luhong Zhang, Yongli Sun, Huawei Yang, Hanrong Bi.  (2016)  Highly efficient and reversible CO2 capture by imidazolate-based ether-functionalized ionic liquids with a capture transforming process.  Journal of the Taiwan Institute of Chemical Engineers,      [PMID:] [10.1016/j.jtice.2016.10.009]

7. Wei Wang, Zhi Yun, Zhigang Tang, Xia Gui.  (2015)  Solubilities of CO2 in some glycol ethers under high pressure by experimental determination and correlation.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2015.08.007]

8. Junxiu Che, Zushuai Wu, Weiyan Shao, Penghao Guo, Yuanyuan Lin, Wenhui Pan, Weidong Zeng, Guoguang Zhang, Chuanbin Wu, Yuehong Xu.  (2015)  Synergetic skin targeting effect of hydroxypropyl-β-cyclodextrin combined with microemulsion for ketoconazole.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:25845772] [10.1016/j.ejpb.2015.03.028]

9. Haoyun Deng, Zhixiong Yang, Mengzhen Zhou, Encai Ou, Yanbing Lu, Qiulan Zhou, Kun Liu, Weijian Xu.  (2024)  Anionic polymerization of (Z)-1,3-pentadiene using Ba/Al/Li trimetallic initiators to synthesize crystalline high trans-1,4-polypentadiene.  POLYMER,      [PMID:] [10.1016/j.polymer.2024.127841]

10. Xue Zou, Mucong Zi, Kai Liu, Tiantian Wu, Daoyi Chen.  (2024)  The molecular chain’s length effect of alcohol and ether for synergistic enhancement with novel kinetic hydrate inhibitors in hydrate inhibition.  FUEL,      [PMID:] [10.1016/j.fuel.2024.131987]

11. Yi Hao, Xingyan Wang, Kaili Wang, Sijie Zhang, Long Zhang, Wenhao Liu, Xueyi Liu, Ruixia Gao, Sicen Wang, Jingang An.  (2025)  Enhanced chemodynamic porphyrin-modified magnetite nanoagents: A triple-action strategy for potent antimicrobial therapy and wound healing.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:39983401] [10.1016/j.jcis.2025.02.068]

12. Ze-Miao Xiong, Zi-Yan Li, Jing-Ru Zhang, Li Guo, Ping Fu, Fei-Peng Du, Yun-Fei Zhang.  (2024)  Enhanced Thermoelectric Properties of Stable n-Type Ferrocene Derivatives-Doped Polyethylenimine/Single-Walled Carbon Nanotube Composite Films.  ACS Applied Materials & Interfaces,      [PMID:39347984] [10.1021/acsami.4c13344]

13. Xiaoyu Cao, Qianyi Huang, Jianxian Zeng, Zhanfang Cao, Xiaoping Huang.  (2025)  Unveiling flotation selectivity and interfacial adsorption mechanism of an oxyether-functionalized xanthate in chalcopyrite-pyrite separation.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.138612]

14. Wenjie Mao, Jiajia Li, Xiaofeng Pan, Joji Tanaka, Wei You, Jian Zhu.  (2025)  RAFT Step-Growth Polymerization via ‘Grafting Through’.  ACS Polymers Au,      [PMID:41657391] [10.1021/acspolymersau.5c00084]

15. Deyi Chen, Xinyuan Wang, Jiuzhou Zhao, Ben Tian, Ruijie Liu, Jiaxin Liu, Qing Wang, Hao Cheng, Caifu Li, Yang Peng, Yun Mou.  (2026)  Low temperature pressureless sintering micron-Ag paste enabling high quality SiC device packaging.  Journal of Materials Research and Technology-JMR&T,      [PMID:] [10.1016/j.jmrt.2026.02.169]