1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
The extracellular matrix (ECM) in the tumor microenvironment not only supports tissue structure, but also continuously regulates immune cell infiltration, migration, activation, and effector functions through matrix deposition, crosslinking, degradation, and spatial reorganization. ECM ...
Glycolytic rate-limiting enzymes determine the key nodes from glucose uptake and flux commitment to pyruvate formation. Hexokinase, phosphofructokinase, and pyruvate kinase respectively control early substrate trapping, irreversible mid-pathway flux commitment, and terminal ATP generation in ...
β-Hydroxybutyrate is one of the predominant ketone body forms in blood and tissues. It is commonly used to evaluate enhanced fatty acid oxidation, hepatic ketogenesis, starvation or fasting status, diabetic ketosis, exercise metabolism, and mitochondrial energy conversion. Compared with ...
Tannic acid–brushite in situ composite bone cement is a degradable calcium phosphate bone repair material in which polyphenolic molecules are introduced into the setting process of brushite bone cement, allowing tannic acid to participate simultaneously in crystal formation, particle bridging, ...
Fixative selection directly affects tissue morphology, antigen preservation, cellular structure, and downstream staining results. Routine tissue fixation, immunostaining, cytological preparation, frozen sectioning, and electron microscopy samples have different requirements for fixatives. ...
Reducing sugar detection is used to determine whether a sample contains sugars with reducing properties and to further evaluate sugar content, enzymatic hydrolysis efficiency, fermentation substrate consumption, or sugar composition in food and biological samples. Fehling’s reagent, ...
Carboxymethyl cellulose (CMC) and its sodium salt (CMC-Na) can be used in cellulase substrate systems, enzyme-producing microbial induction cultures, exogenous polysaccharide models in soil studies, particle suspension stabilization, suspension dosing of poorly soluble compounds, film-forming ...
Bilirubin detection is mainly used to evaluate changes related to heme metabolism, hepatobiliary excretory function, cholestasis, neonatal jaundice, and hepatocellular injury. In clinical and research settings, total bilirubin, direct bilirubin, and indirect bilirubin are commonly measured. ...
Electrode solutions are used in multiple steps, including calibration, storage, soaking, cleaning, internal filling, ionic strength adjustment, and standard curve establishment. For pH electrodes, ORP combination electrodes, conductivity electrodes, and ion-selective electrodes, solution ...