Heparan Sulfate - Potency ≥ 50IU/mg , CAS No.9050-30-0

CAS: 9050-30-0 Cat. No.: H304938 Molecular Weight: 593.47 (monomer) EC Number: 232-939-9 PubChem CID: 137699201

GRADE & PURITY Potency ≥ 50IU/mg

Synonyms

Heparansulfate | azane;(3R,4R,5S,6R)-3-[(2S,3S,4R,5R)-5-[(2R,3S,4S,5R)-6-carboxylato-4-hydroxy-5-methoxy-3-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-3-(sulfonatoamino)-6-(sulfonatooxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-[(3S,4R,5S,6R)-6-methoxy-5-(sulfonatoamin

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

Heparansulfate | azane;(3R, 4R, 5S, 6R)-3-[(2S, 3S, 4R, 5R)-5-[(2R, 3S, 4S, 5R)-6-carboxylato-4-hydroxy-5-methoxy-3-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-3-(sulfonatoamino)-6-(sulfonatooxymethyl)oxan-2-yl]oxy-4, 5-dihydroxy-6-[(3S, 4R, 5S, 6R)-6-methoxy-5-(sulfonatoamin

Specifications & Purity

Potency ≥ 50IU/mg

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: COC1C(C(C(OC1C(=O)[O-])OC2C(OC(C(C2O)NS(=O)(=O)[O-])OC3C(C(C(OC3C(=O)[O-])OC4C(OC(C(C4OS(=O)(=O)[O-])NS(=O)(=O)[O-])OC)COS(=O)(=O)[O-])O)O)COS(=O)(=O)[O-])OS(=O)(=O)[O-])O.N
• IUPAC Name: azane;(3R,4R,5S,6R)-3-[(2S,3S,4R,5R)-5-[(2R,3S,4S,5R)-6-carboxylato-4-hydroxy-5-methoxy-3-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-3-(sulfonatoamino)-6-(sulfonatooxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-[(3S,4R,5S,6R)-6-methoxy-5-(sulfonatoamino)-4-sulfonatooxy-2-(sulfonatooxymethyl)oxan-3-yl]oxyoxane-2-carboxylate
• InChIKey: XSIDRQZFWFCLLF-VYLUHDBLSA-F
• INCHI: 1S/C26H44N2O39S6.H3N/c1-55-16-12(32)18(67-73(52,53)54)26(65-19(16)21(33)34)61-13-5(3-57-70(43,44)45)60-24(7(9(13)29)27-68(37,38)39)63-17-10(30)11(31)25(64-20(17)22(35)36)62-14-6(4-58-71(46,47)48)59-23(56-2)8(28-69(40,41)42)15(14)66-72(49,50)51;/h5-20,23-32H,3-4H2,1-2H3,(H,33,34)(H,35,36)(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);1H3/p-8/t5?,6?,7-,8-,9+,10+,11-,12-,13-,14-,15+,16+,17+,18-,19?,20?,23+,24-,25+,26+;/m0./s1
• Isomeric SMILES: CO[C@@H]1[C@@H]([C@@H]([C@@H](OC1C(=O)[O-])O[C@@H]2[C@@H]([C@@H]([C@@H](OC2COS(=O)(=O)[O-])O[C@@H]3[C@@H]([C@@H]([C@@H](OC3C(=O)[O-])O[C@@H]4[C@@H]([C@@H]([C@@H](OC4COS(=O)(=O)[O-])OC)NS(=O)(=O)[O-])OS(=O)(=O)[O-])O)O)NS(=O)(=O)[O-])O)OS(=O)(=O)[O-])O.N
• PubChem CID: 137699201
• Molecular Weight: 593.47 (monomer)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Fatty Acyls
      • Subclass Fatty acyl glycosides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Fatty Acyls
• Subclass: Fatty acyl glycosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Fatty acyl glycosides of mono- and disaccharides
• Alternative Parents: O-glucuronides Sulfated fatty acids Short-chain hydroxy acids and derivatives Hydroxy fatty acids Heterocyclic fatty acids Sulfuric acid monoesters Sulfuric acid monoamides Pyrans Oxanes Monosaccharides Dicarboxylic acids and derivatives Alkyl sulfates Secondary alcohols Oxacyclic compounds Dialkyl ethers Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Organic anions
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Fatty acyl glycoside of mono- or disaccharide - O-glucuronide - 1-o-glucuronide - Glucuronic acid or derivatives - Sulfated fatty acid - Short-chain hydroxy acid - Hydroxy fatty acid - Heterocyclic fatty acid - Fatty acid - Sulfuric acid ester - Alkyl sulfate - Sulfate-ester - Sulfuric acid monoester - Pyran - Oxane - Sulfuric acid monoamide - Monosaccharide - Dicarboxylic acid or derivatives - Organic sulfuric acid or derivatives - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Ether - Dialkyl ether - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Alcohol - Organic anion - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as fatty acyl glycosides of mono- and disaccharides. These are compounds composed of a mono- or disaccharide moiety linked to one hydroxyl group of a fatty alcohol or of a phosphorylated alcohol (phosphoprenols), a hydroxy fatty acid or to one carboxyl group of a fatty acid (ester linkage) or to an amino alcohol.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Methanol (Slightly), Water (Slightly)
• Sensitivity: Moisture sensitive.
• Melt Point(°C): >216°C (dec.)

References

1. Jiahua Duan, Gaofei Qian, Huikang Zhang, Feifan Wang, Qiang Tian, Dong Lei, Jianning Zhao.  (2025)  3D-Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB-LG4 Fusion Protein Promotes Bone Regeneration.  Advanced Science,      [PMID:40145866] [10.1002/advs.202414362]

2. Jianjian Ji, Yingcai Xiong, Keyu Tao, Tao Li, Weiying Ou, Yinghui Zhou, Wenyang Zhang, Ruogu Qi, Shouchuan Wang.  (2024)  Resveratrol inhibits respiratory syncytial virus replication by targeting heparan sulfate proteoglycan.  Food & Function,      [PMID:38270052] [10.1039/D3FO05131E]

3. Yu-Ting Li, Jia-Lu Pei, Tong Huan, Yue Wu, Ye-Wang Zhang.  (2025)  Enhanced soluble expression and improved catalytic efficiency of heparinase II by fusion of GST tag to the backside of the active pocket.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41005396] [10.1016/j.ijbiomac.2025.147877]

4. Yushuang Wei, Wenwen Li, Rong Xu, Cheng Xu, Xiangyang Li, Ning Li, Fengdan Xu, Kai Yang, Bing Yuan.  (2025)  Multivalent Co-assembly of LL37-CpG nanoparticles: Enhanced immune response through activating multiple cell internalization pathways.  Materials Today Bio,      [PMID:40621182] [10.1016/j.mtbio.2025.102011]

5. Nana Ma, Xueling Dong, Ruinan Li, Chuang Du, Yawen Wang, Jiaxin Bai, Run Ran, Xulin Liu, Dianshuo Zhang, Haikui Zou.  (2026)  Coptisine Chloride: A Natural Isoquinoline Alkaloid as a Dual-Responsive Aggregation-Induced Emission Sensor for Heparin and Protamine.  Chemosensors,  14  (2): (51).  [PMID:] [10.3390/chemosensors14020051]