L-Histidine - Animal Free, USP, Moligand™, Ph.Eur., for cell culture , Activator of carbonic anhydrase 1;Activator of carbonic anhydrase 14;Activator of carbonic anhydrase 5A;Activator of carbonic anhydrase 7, CAS No.71-00-1, Activator of carbonic anhydrase 1;Activator of carbonic anhydrase 14;Activator of carbonic anhydrase 5A;Activator of carbonic anhydrase 7

CAS: 71-00-1 Cat. No.: H108261 Summenformel: C6H9N3O2 Molekulargewicht: 155.15 Beilstein Registry Number: 84088 EG-Nummer: 200-745-3
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QUALITÄT & REINHEIT Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. USP ? United States Pharmacopeia grade — meets USP monograph specs for pharmaceutical use. Use for drug manufacturing, QC, and applications requiring US compendial compliance. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Ph.Eur. ? European Pharmacopoeia grade — conforms to Ph.Eur. monographs across EU member states. Use for pharmaceutical work needing European compendial compliance. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements.
Synonyms
His | NSC 137773 | [3H]histidine | [3H]-histidine | amino-4-imidazoleproprionic acid | BDBM181118 | L-Histidin | L-beta-(4-Imidazolyl)-alpha-alanin | L-Histidine, non-animal source | bmse001015 | HISTIDINE (MART.) | Histidine (USP/INN) | L-His | HISTIDINE
Storage
Store at 2-8°C,Protected from light
Shipped In
Wet ice
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Größe
Deutschland (EU)
USA*
Preis
Menge
25g
H108261-25g
—
7 Auf Lager
38,96€
100g
H108261-100g
—
5 Auf Lager
126,60€
500g
H108261-500g
—
2 Auf Lager
506,67€
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Warum diese Qualität

Animal Free, USP, Moligand™, Ph.Eur., for cell culture Animal Free,für die Zellkultur,Moligand™,Ph.Eur.,USP für empfindliche chromatographische und analytische Workflows, die minimale Basislinieninterferenzen erfordern.

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Lagerung & Versand

Store at 2-8°C,Protected from light Versand Wet ice. Genaue Spezifikationen finden Sie im chargenspezifischen COA.

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Qualitätsdokumente

SDS, COA, Datenblatt und Spezifikationsblatt stehen zum Download bereit. Chargenspezifische COA über Chargennummernsuche abrufbar.

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Literaturbeleg

In 1264 peer-reviewten Publikationen zu Chromatographie, organischer Synthese und Kreuzkupplungsreaktionen zitiert.

Übersicht

L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-FC) for the selection of yeast transformants. It has also been used as a component of adult mouse keratinocyte growth medium.

Spezifikationen

Synonyme
His | NSC 137773 | [3H]histidine | [3H]-histidine | amino-4-imidazoleproprionic acid | BDBM181118 | L-Histidin | L-beta-(4-Imidazolyl)-alpha-alanin | L-Histidine, non-animal source | bmse001015 | HISTIDINE (MART.) | Histidine (USP/INN) | L-His | HISTIDINE
Spezifikationen & Reinheit
Animal Free, USP, Moligand™, Ph.Eur., for cell culture
Biochemische und physiologische Mechanismen
An essential amino acid, precursor to histamine and a component of carnosine.
Storage
Store at 2-8°C,Protected from light
Verschickt in
Wet ice
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Note
Animal Free, für die Zellkultur, Moligand™, Ph.Eur., USP
Aktionsart
ACTIVATOR
Mechanismus der Wirkung
Activator of carbonic anhydrase 1;Activator of carbonic anhydrase 14;Activator of carbonic anhydrase 5A;Activator of carbonic anhydrase 7
Namen und Kennungen
Pubchem Sid
Kanonisches Lächeln
C1=C(NC=N1)CC(C(=O)O)N
IUPAC Name
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid
InChIKey
HNDVDQJCIGZPNO-YFKPBYRVSA-N
INCHI
1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
Isomere SMILES
C1=C(NC=N1)C[C@@H](C(=O)O)N
WGK Deutschland
1
RTECS
MS3070000
Alternative CAS-Nummer
71-00-1,26062-48-6
MeSH-Eintrag
Histidine;Histidine, L isomer;Histidine, L-isomer;L-Histidine;L-isomer Histidine
Molekulargewicht
155.15
Beilstein
84088
Reaxy-Rn
7800
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7800&ln=

Dokumentation

📋 Sicherheitsdatenblatt (SDS)

Umfassendes Dokument zu Gefahren, Handhabung, Lagerung und Einhaltung regulatorischer Vorschriften.

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Erweiterte Daten

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
KlasseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentHistidine and derivatives
Alternative Parents L-alpha-amino acids  Imidazolyl carboxylic acids and derivatives  Aralkylamines  Heteroaromatic compounds  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Histidine or derivatives - Alpha-amino acid - L-alpha-amino acid - Imidazolyl carboxylic acid derivative - Aralkylamine - Azole - Imidazole - Heteroaromatic compound - Amino acid - Carboxylic acid - Azacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Primary amine - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Aromatic heteromonocyclic compound
BeschreibungThis compound belongs to the class of organic compounds known as histidine and derivatives. These are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Common amino acids
3D-Struktur
Interaktives chemisches Strukturmodell





Zugehörige Ziele (menschlich)
CYP3A4 Tclin Cytochrome P450 3A4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA5A Tclin Carbonic anhydrase 5A, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA1 Tclin Carbonic anhydrase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA14 Tclin Carbonic anhydrase 14 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA7 Tclin Carbonic anhydrase 7 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA3 Tclin Carbonic anhydrase III (753 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA6 Tclin Carbonic anhydrase VI (993 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA5B Tclin Carbonic anhydrase VB (957 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA5A Tclin Carbonic anhydrase VA (1168 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA14 Tclin Carbonic anhydrase XIV (1305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HAL Tbio Histidase (20 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Skin (286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC16A10 SLC16A10 protein (28 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Zugehörige Ziele (nicht menschlich)
Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ca13 Carbonic anhydrase XIII (322 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA4 Carbonic anhydrase IV (1713 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Carbonic anhydrase (69 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ca15 Carbonic anhydrase 15 (173 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAN2 Carbonic anhydrase 2 (140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAP1 General amino-acid permease GAP1 (481 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Wirkungsmechanismen
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

28 results found

Lot NumberCertificate TypeDatumArtikel
G2616467G2616467Certificate of AnalysisJul 06, 2026 H108261
G2616466G2616466Certificate of AnalysisJul 06, 2026 H108261
G2616465G2616465Certificate of AnalysisJul 06, 2026 H108261
K2524366K2524366Certificate of AnalysisNov 11, 2025 H108261
K2524362K2524362Certificate of AnalysisNov 11, 2025 H108261
J2628603J2628603Certificate of AnalysisNov 11, 2025 H108261
E2625042E2625042Certificate of AnalysisNov 11, 2025 H108261
G2511563G2511563Certificate of AnalysisJul 01, 2025 H108261
G2511562G2511562Certificate of AnalysisJul 01, 2025 H108261
G2511561G2511561Certificate of AnalysisJul 01, 2025 H108261
G2511300G2511300Certificate of AnalysisJul 01, 2025 H108261
G2511560G2511560Certificate of AnalysisJul 01, 2025 H108261
D2523168D2523168Certificate of AnalysisApr 11, 2025 H108261
L2427164L2427164Certificate of AnalysisFeb 24, 2024 H108261
D2502057D2502057Certificate of AnalysisFeb 24, 2024 H108261
C2409168C2409168Certificate of AnalysisFeb 24, 2024 H108261
C2409167C2409167Certificate of AnalysisFeb 24, 2024 H108261
C2409166C2409166Certificate of AnalysisFeb 24, 2024 H108261
J2215273J2215273Certificate of AnalysisAug 02, 2022 H108261
J2215283J2215283Certificate of AnalysisAug 02, 2022 H108261
J2215304J2215304Certificate of AnalysisAug 02, 2022 H108261
B2310224B2310224Certificate of AnalysisAug 02, 2022 H108261
K2327094K2327094Certificate of AnalysisAug 02, 2022 H108261
D2502125D2502125Certificate of AnalysisDec 09, 2021 H108261
B2310230B2310230Certificate of AnalysisDec 09, 2021 H108261
A2219459A2219459Certificate of AnalysisDec 09, 2021 H108261
A2219458A2219458Certificate of AnalysisDec 09, 2021 H108261
A2219215A2219215Certificate of AnalysisDec 09, 2021 H108261
Chemische und physikalische Eigenschaften
LöslichkeitSoluble in water (15 mg/ml at 20 °C).
EmpfindlichkeitLight sensitive.
Spezifische Drehung [α]13 ° (C=11, 6mol/L HCl)
Schmelzpunkt (°C)282°C
Molekulargewicht155.150 g/mol
XLogP3-3.200
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass155.069 Da
Monoisotopic Mass155.069 Da
Topological Polar Surface Area92.000 Ų
Heavy Atom Count11
Formal Charge0
Complexity151.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
FAQs und Artikel
Chelating Agents
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Tuning Logic of Imidazole Heteroaromatic Building Blocks: How Dual Nitrogen Sites and Substitution / Salt Forms / Ring Fusion Modulate Charge, Hydrogen Bonding, and Coordination (with Tables A–E)
Glutaraldehyde-mediated Microbial Inactivation: Chemical Mechanisms, Determinants, and Key Validation Considerations
Invertebrate Oxygen Carrier Proteins in Immunology and Vaccine Research
β-Acyloxy Alkenyl Amides (AAAs): A New Approach to Amide Bond and Peptide Bond Construction Worth Attention
Silicon Reagent-Assisted Peptide Synthesis: Research Progress and Methodological Value of Peptide Bond Formation from Unprotected Substrates
From Analytical Instrument to Synthetic Platform: A New Strategy for Reconstructing Automated Flow Solid-Phase Peptide Synthesis with Standard Analytical HPLC
Analysis of Hydrolyzed Pearl as a Cosmetic Raw Material: Preparation Process, Active Components, and Skincare Formulation Applications
Skin Anti-Aging Mechanisms of Carnosine and Decarboxy Carnosine: Active Carbonyl Scavenging, Oxidative-Stress Buffering, and Inhibition of Collagen Glycation Cross-Linking
Moisturizing Mechanism of Polyglutamic Acid: From the γ-Glutamyl Structure to Hydration Networks and Surface Film-Forming Behavior
Structure, Stratum Corneum Distribution, and Stratum Corneum Conditioning Mechanism of Capryloyl Salicylic Acid: Barrier Effects and Safety Evaluation
Exosome-Related Ingredients in Skincare Products: Sources and Preparation, Quality Control, Evidence of Efficacy, and Safety Assessment
Mechanisms by Which Fructan-Rich Ophiopogon japonicus Tuberous Root Extract Supports Skin Moisturization and Barrier Function
Multilevel Moisturizing Mechanisms of Sodium Hyaluronate and Its Derivatives: Molecular Weight Modulation, Crosslinking, Acetylation, and Major Sites of Action
The Combination Logic of Palmitoyl Tripeptide-1 and Palmitoyl Pentapeptide-4: Skin Delivery, Matrix Signaling, and Regulation of Collagen Homeostasis
Structural Characteristics of Ergothioneine, OCTN1-Mediated Uptake by Skin Cells, and Antioxidant Mechanisms
Copper Tripeptide GHK-Cu and Skin Repair: From Copper Coordination Chemistry to Extracellular Matrix Remodeling
Citations of This Product
Lösungsrechner
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