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Ribosomal protein s6 kinase alpha-5 (RPS6KA5)

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  1. RepSox
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    RepSox
    CAS: 446859-33-2 EC Number: 663-924-9 Formula: C17H13N5 Molecular Weight: 287.32
    ≥98%
    In Stock Item #: R125531
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    Technical Identifiers
    IUPAC Name
    2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
    SMILES
    CC1=NC(=CC=C1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
    InChIKey
    LBPKYPYHDKKRFS-UHFFFAOYSA-N
    InChI
    1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
    Synonyms
    ALK5 Inhibitor II | 2-(3-(6-methyl-2-pyridinyl)-1h-pyrazol-4-yl)-1,5-naphthyridine | DTXSID80332295 | AKOS016009677 |...
  2. RMM 46
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    RMM 46
    CAS: 1307896-46-3 PubChem CID: 67206797 Formula: C24H26N4O5 Molecular Weight: 450.5
    ≥98%(HPLC)
    Out of Stock Item #: R288282
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    IUPAC Name
    (E)-2-cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
    SMILES
    CC(C)(CO)NC(=O)C(=CC1=CC2=C(C=C1)NN=C2C3=CC(=C(C(=C3)OC)OC)OC)C#N
    InChIKey
    FCCMYBKAZCDQGX-LZYBPNLTSA-N
    InChI
    1S/C24H26N4O5/c1-24(2,13-29)26-23(30)16(12-25)8-14-6-7-18-17(9-14)21(28-27-18)15-10-19(31-3)22(33-5)20(11-15)32-4/h6-11,29H,13H2,1-5H3,(H,26,30)(H,27,show more
    Synonyms
    2-Cyano-N-(2-hydroxy-1,1-dimethylethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]-2-propenamide
  3. H-89, Inhibitor of protein kinase; cAMP-dependent; catalytic; alpha subunit
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    H-89, Inhibitor of protein kinase; cAMP-dependent; catalytic; alpha subunit
    CAS: 127243-85-0 EC Number: 675-767-3 Formula: C20H20BrN3O2S Molecular Weight: 446.36
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: N302321
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    IUPAC Name
    N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide
    SMILES
    C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNCC=CC3=CC=C(C=C3)Br
    InChIKey
    ZKZXNDJNWUTGDK-NSCUHMNNSA-N
    InChI
    1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+
    Synonyms
    N-[2-(p-Bromocinnamylamino)ethyl]-5-Isoquinoline Sulfonamide, 98% | DTXSID801022528 | Protein kinase inhibitor H89 | ...
  4. RepSox (E-616452)
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    RepSox (E-616452)
    CAS: 446859-33-2 EC Number: 663-924-9 Formula: C17H13N5 Molecular Weight: 287.32
    10mM in DMSO
    In Stock Item #: R408431
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    Technical Identifiers
    Synonyms
    SJN 2511,ALK5 Inhibitor II | 1,5-Naphthyridine, 2-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-
  5. no_selection
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    4-[1-ethyl-7-(piperazin-1-ylmethyl)imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine, Inhibitor of ribosomal protein S6 kinase A5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: E608979
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    Technical Identifiers
    IUPAC Name
    4-[1-ethyl-7-(piperazin-1-ylmethyl)imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
    SMILES
    CCn1c(nc2c1c(CN1CCNCC1)cnc2)c1nonc1N
    InChIKey
    OXZLPOLYTISTQY-UHFFFAOYSA-N
    InChI
    1S/C15H20N8O/c1-2-23-13-10(9-22-5-3-17-4-6-22)7-18-8-11(13)19-15(23)12-14(16)21-24-20-12/h7-8,17H,2-6,9H2,1H3,(H2,16,21)
    Synonyms
    compound 24
  6. no_selection
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    SB-747651A, Inhibitor of ribosomal protein S6 kinase A5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S613470
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    Technical Identifiers
    IUPAC Name
    N-[[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[5,4-d]pyridin-7-yl]methyl]piperidin-4-amine
    SMILES
    CCn1c(nc2c1c(CNC1CCNCC1)cnc2)c1nonc1N
    InChIKey
    MBCJUIJWPYUEBX-UHFFFAOYSA-N
    InChI
    1S/C16H22N8O/c1-2-24-14-10(8-20-11-3-5-18-6-4-11)7-19-9-12(14)21-16(24)13-15(17)23-25-22-13/h7,9,11,18,20H,2-6,8H2,1H3,(H2,17,23)
    Synonyms
    compound 26
  7. Ro31-8220
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    Ro31-8220
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: R613239
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    IUPAC Name
    3-[3-[4-(1-methylindol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propylsulfanylmethanimidamide
    SMILES
    NC(=N)SCCCn1cc(c2c1cccc2)C1=C(C(=O)NC1=O)c1cn(c2c1cccc2)C
    InChIKey
    DSXXEELGXBCYNQ-UHFFFAOYSA-N
    InChI
    1S/C25H23N5O2S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12H2,1Hshow more
    Synonyms
    3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl carbamimidothioate | Bisi...
  9. p38α inhibitor 2
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    p38α inhibitor 2
    CAS: 1095003-80-7 PubChem CID: 25145735 Formula: C27H33N5O3 Molecular Weight: 475.58
    ≥98%
    Out of Stock Item #: P647104
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    Technical Identifiers
    IUPAC Name
    N-cyclopropyl-4-methyl-3-[3-[2-[2-[2-(methylamino)ethoxy]phenyl]propan-2-ylamino]-2-oxopyrazin-1-yl]benzamide
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC2CC2)N3C=CN=C(C3=O)NC(C)(C)C4=CC=CC=C4OCCNC
    InChIKey
    SAZVRXTVWZAHBI-UHFFFAOYSA-N
    InChI
    1S/C27H33N5O3/c1-18-9-10-19(25(33)30-20-11-12-20)17-22(18)32-15-13-29-24(26(32)34)31-27(2,3)21-7-5-6-8-23(21)35-16-14-28-4/h5-10,13,15,17,20,28H,11-12show more
  10. 4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
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    4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
    CAS: 607368-87-6 PubChem CID: 23646578 Formula: C10H10N6O Molecular Weight: 230.23
    Out of Stock Item #: E669231
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    Technical Identifiers
    IUPAC Name
    4-(1-ethylimidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
    SMILES
    CCN1C2=C(C=NC=C2)N=C1C3=NON=C3N
    InChIKey
    UGHABJRZQKZAHP-UHFFFAOYSA-N
    InChI
    1S/C10H10N6O/c1-2-16-7-3-4-12-5-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3,(H2,11,15)
    Synonyms
    4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine | 4-(1-ethylimidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadi...
  11. [2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone
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    [2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone
    Formula: C15H18N8O2 Molecular Weight: 342.36
    Out of Stock Item #: A669204
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    Technical Identifiers
    IUPAC Name
    [2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone
    SMILES
    CCN1C2=C(C=NC=C2C(=O)N3CCC(C3)N)N=C1C4=NON=C4N
    InChIKey
    PHWHNHYZZNJPLB-QMMMGPOBSA-N
    InChI
    1S/C15H18N8O2/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21)/t8-/m0/s1
    Synonyms
    SB-772077B | BDBM50365218 | NSC756491 | NSC-756491 | SB-7720770B | NCGC00241969-05 | AB01092286-01
  12. 1，2，5-Oxadiazol-3-amine， 4-(1-ethyl-1H-benzimidazol-2-yl)-
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    1，2，5-Oxadiazol-3-amine， 4-(1-ethyl-1H-benzimidazol-2-yl)-
    CAS: 293760-29-9 PubChem CID: 599038 Formula: C11H11N5O Molecular Weight: 229.24
    ≥95%
    Out of Stock Item #: O769616
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    Technical Identifiers
    IUPAC Name
    4-(1-ethylbenzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
    SMILES
    CCN1C2=CC=CC=C2N=C1C3=NON=C3N
    InChIKey
    HCRQPXYLXXLKPT-UHFFFAOYSA-N
    InChI
    1S/C11H11N5O/c1-2-16-8-6-4-3-5-7(8)13-11(16)9-10(12)15-17-14-9/h3-6H,2H2,1H3,(H2,12,15)
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