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Serine/threonine-protein kinase smg1 (SMG1)

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  1. WYE-125132 (WYE-132)
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    WYE-125132 (WYE-132)
    CAS: 1144068-46-1 PubChem CID: 25260757 Formula: C27H33N7O4 Molecular Weight: 519.61
    ≥98%
    In Stock Item #: W128041
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    Technical Identifiers
    IUPAC Name
    1-[4-[1-(1,4-dioxaspiro[4.5]decan-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-3-methylurea
    SMILES
    CNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCC5(CC4)OCCO5)C(=N2)N6CC7CCC(C6)O7
    InChIKey
    QLHHRYZMBGPBJG-UHFFFAOYSA-N
    InChI
    1S/C27H33N7O4/c1-28-26(35)30-18-4-2-17(3-5-18)23-31-24(33-15-20-6-7-21(16-33)38-20)22-14-29-34(25(22)32-23)19-8-10-27(11-9-19)36-12-13-37-27/h2-5,14,1show more
    Synonyms
    EX-A2183 | WYE125132 | WYE-125132 | 3-(4-methoxyphenyl)-1-methyl-5-p-tolyl-1H-pyrazole | NCGC00346635-01 | Q27163233 ...
  2. CGP60474
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    CGP60474
    CAS: 164658-13-3 Formula: C18H18ClN5O Molecular Weight: 355.82
    ≥99%
    In Stock Item #: C125354
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    Technical Identifiers
    IUPAC Name
    3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol
    SMILES
    C1=CC(=CC(=C1)Cl)NC2=NC=CC(=N2)C3=CC(=NC=C3)NCCCO
    InChIKey
    IYNDTACKOAXKBJ-UHFFFAOYSA-N
    InChI
    1S/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24)
    Synonyms
    8II | BCP27893 | HMS3265E05 | GNF-Pf-88 | HY-11009 | Q27163218 | A910858 | cid_644215 | D97331 | HMS2218H05 | SCHEMBL...
  3. WYE-125132 (WYE-132)
    Wish List Compare
    WYE-125132 (WYE-132)
    CAS: 1144068-46-1 PubChem CID: 25260757 Formula: C27H33N7O4 Molecular Weight: 519.61
    10mM in DMSO
    In Stock Item #: W408714
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    Technical Identifiers
    Synonyms
    Urea, N-[4-[1-(1,4-dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]ph...
  4. no_selection
    Wish List Compare
    1-[4-[4-[2-[4-chloro-3-(diethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma;Inhibitor of SMG1 nonsense mediated
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: C608659
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    Technical Identifiers
    IUPAC Name
    1-[4-[4-[2-[4-chloro-3-(diethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
    SMILES
    CNC(=O)Nc1ccc(cc1)c1nccc(c1)c1ccnc(n1)Nc1ccc(c(c1)S(=O)(=O)N(CC)CC)Cl
    InChIKey
    RZFJBSIAXYEPBX-UHFFFAOYSA-N
    InChI
    1S/C27H28ClN7O3S/c1-4-35(5-2)39(37,38)25-17-21(10-11-22(25)28)32-26-31-15-13-23(34-26)19-12-14-30-24(16-19)18-6-8-20(9-7-18)33-27(36)29-3/h6-17H,4-5H2show more
    Synonyms
    compound 11j
  5. hSMG-1 inhibitor 11j
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    hSMG-1 inhibitor 11j
    CAS: 1402452-15-6 PubChem CID: 71458575 Formula: C27H28ClN7O3S Molecular Weight: 566.07
    ≥99%
    Out of Stock Item #: H647595
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-[4-[4-[2-[4-chloro-3-(diethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
    SMILES
    CCN(CC)S(=O)(=O)C1=C(C=CC(=C1)NC2=NC=CC(=N2)C3=CC(=NC=C3)C4=CC=C(C=C4)NC(=O)NC)Cl
    InChIKey
    RZFJBSIAXYEPBX-UHFFFAOYSA-N
    InChI
    1S/C27H28ClN7O3S/c1-4-35(5-2)39(37,38)25-17-21(10-11-22(25)28)32-26-31-15-13-23(34-26)19-12-14-30-24(16-19)18-6-8-20(9-7-18)33-27(36)29-3/h6-17H,4-5H2show more
  7. hSMG-1 inhibitor 11e
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    hSMG-1 inhibitor 11e
    CAS: 1402452-10-1 PubChem CID: 71458574 Formula: C26H27N7O3S Molecular Weight: 517.60
    ≥99%
    Out of Stock Item #: H650955
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-[4-[4-[2-[3-(dimethylsulfamoyl)-4-methylanilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
    SMILES
    CC1=C(C=C(C=C1)NC2=NC=CC(=N2)C3=CC(=NC=C3)C4=CC=C(C=C4)NC(=O)NC)S(=O)(=O)N(C)C
    InChIKey
    FOFHDVOENOAIGR-UHFFFAOYSA-N
    InChI
    1S/C26H27N7O3S/c1-17-5-8-21(16-24(17)37(35,36)33(3)4)30-25-29-14-12-22(32-25)19-11-13-28-23(15-19)18-6-9-20(10-7-18)31-26(34)27-2/h5-16H,1-4H3,(H2,27,show more
  8. CGP60474
    Wish List Compare
    CGP60474
    CAS: 164658-13-3 Formula: C18H18ClN5O Molecular Weight: 355.82
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: C1494349
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  9. hSMG-1 inhibitor 11j
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    hSMG-1 inhibitor 11j
    CAS: 1402452-15-6 PubChem CID: 71458575 Formula: C27H28ClN7O3S Molecular Weight: 566.07
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: H1495639
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    Pricing & Pack Sizes
    Technical Identifiers
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