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  1. GSA10, Allosteric modulator of SMO
    CAS: 300833-95-8 EG-Nummer: 808-811-9 Summenformel: C26H30N2O5 Molekulargewicht: 450.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: G275761
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    propyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate
    SMILES
    CCCCCCN1C2=CC=CC=C2C(=C(C1=O)C(=O)NC3=CC=C(C=C3)C(=O)OCCC)O
    InChIKey
    MDLUYYGRCGDKGL-UHFFFAOYSA-N
    InChI
    1S/C26H30N2O5/c1-3-5-6-9-16-28-21-11-8-7-10-20(21)23(29)22(25(28)31)24(30)27-19-14-12-18(13-15-19)26(32)33-17-4-2/h7-8,10-15,29H,3-6,9,16-17H2,1-2H3,(show more
    Synonyme
    AS-16537 | AKOS000624567 | GTPL10326 | GSA 10; GSA-10 | J-017772 | STK034810 | 4-[[(1-Hexyl-1,2-dihydro-2-oxo-3-quino...
  2. Robotnikinin
    CAS: 1132653-79-2 PubChem CID: 25109985 Summenformel: C25H27ClN2O4 Molekulargewicht: 454.95
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: R346308
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    N-[(4-chlorophenyl)methyl]-2-[(2R,6S,8E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide
    SMILES
    C1CC(=O)OC(CNC(=O)C(CC=C1)CC(=O)NCC2=CC=C(C=C2)Cl)C3=CC=CC=C3
    InChIKey
    DRDSZZCLAHXSAE-BQIDRLATSA-N
    InChI
    1S/C25H27ClN2O4/c26-21-13-11-18(12-14-21)16-27-23(29)15-20-9-5-2-6-10-24(30)32-22(17-28-25(20)31)19-7-3-1-4-8-19/h1-5,7-8,11-14,20,22H,6,9-10,15-17H2,show more
    Synonyme
    N-(4-chlorobenzyl)-2-((2R,6S,E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl)acetamide | N-[(4-chlorophenyl)me...
  3. 1-Methyladenosine
    CAS: 15763-06-1 Summenformel: C11H15N5O4 Molekulargewicht: 281.27
    Feststoff ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: M303015
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    (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol
    SMILES
    CN1C=NC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)O
    InChIKey
    GFYLSDSUCHVORB-IOSLPCCCSA-N
    InChI
    1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1
    Synonyme
    H10051 | AC-32347 | Adenosine, N,6-didehydro-1,9-dihydro-1-methyl- | HY-113081 | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6...
  4. Neurodazine
    CAS: 937807-66-4 Summenformel: C27H21ClN2O3 Molekulargewicht: 456.93
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: N275013
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    2-[5-(3-chlorophenyl)furan-2-yl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
    SMILES
    COC1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(O3)C4=CC(=CC=C4)Cl)C5=CC=C(C=C5)OC
    InChIKey
    FEEOFPAEDSMOTO-UHFFFAOYSA-N
    InChI
    1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)
    Synonyme
    Neurodazine - CAS 937807-66-4 | Q27166384 | BRD-K22631935-001-01-9 | CHEBI:94546 | NCGC00344091-03 | 2-[5-(3-Chloro-p...
  5. SMANT hydrochloride
    CAS: 1177600-74-6 PubChem CID: 2900213 Summenformel: C16H24BrClN2O Molekulargewicht: 375.73
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S288275
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    N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide;hydrochloride
    SMILES
    CC1CC(CN(C1)CCC(=O)NC2=CC=C(C=C2)Br)C.Cl
    InChIKey
    XQESCHFXROUCOQ-UHFFFAOYSA-N
    InChI
    1S/C16H23BrN2O.ClH/c1-12-9-13(2)11-19(10-12)8-7-16(20)18-15-5-3-14(17)4-6-15;/h3-6,12-13H,7-11H2,1-2H3,(H,18,20);1H
    Synonyme
    N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamide hydrochloride | N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-y...
  6. Itraconazole-d5 (major)
    CAS: 1217510-38-7 Summenformel: C35H33D5Cl2N8O4 Molekulargewicht: 710.66
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: I343299
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    4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(3,3,4,4,4-pentadeushow more
    SMILES
    CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
    InChIKey
    VHVPQPYKVGDNFY-VXTATNQMSA-N
    InChI
    1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43show more
    Synonyme
    HY-17514S | Itraconazole-d5 (major) | 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-di...
  7. JK184
    CAS: 315703-52-7 Summenformel: C19H18N4OS Molekulargewicht: 350.44
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: J169510
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    N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine
    SMILES
    CCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C
    InChIKey
    ROYXIPOUVGDTAO-UHFFFAOYSA-N
    InChI
    1S/C19H18N4OS/c1-3-24-15-9-7-14(8-10-15)21-19-22-16(12-25-19)18-13(2)20-17-6-4-5-11-23(17)18/h4-12H,3H2,1-2H3,(H,21,22)
    Synonyme
    AKOS016003923 | DTXSID70360042 | B2693-462944 | BDBM50249523 | N-(4-ETHOXYPHENYL)-4-{2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-...
  8. Jervine
    CAS: 469-59-0 EG-Nummer: 207-417-9 Summenformel: C27H39NO3 Molekulargewicht: 425.6
    Feststoff ≥97%(HPLC)
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: J135916
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    (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,show more
    SMILES
    CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
    InChIKey
    CLEXYFLHGFJONT-DNMILWOZSA-N
    InChI
    1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2show more
    Synonyme
    NSC7520 | NSC-7520 | CCG-208226 | Spiro[9H-benzo[a]fluorene-9,2-b]-pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7...
  9. Vismodegib (GDC-0449), Smoothened homolog inhibitor
    CAS: 879085-55-9 EG-Nummer: 806-752-3 PubChem CID: 24776445 Summenformel: C19H14Cl2N2O3S Molekulargewicht: 421.31
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: V127477
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    2-chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide
    SMILES
    CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
    InChIKey
    BPQMGSKTAYIVFO-UHFFFAOYSA-N
    InChI
    1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)
    Synonyme
    Vismodegib (USAN/INN) | 2-Chloro-N-(4-chloro-3-(pyridin-2-yl)-phenyl)-4-(methylsulfonyl)benzamide | 2-chloro-N-(4-chl...
  10. Cyclopamine, Antagonist of SMO
    CAS: 4449-51-8 EG-Nummer: 628-058-8 Summenformel: C27H41NO2 Molekulargewicht: 411.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: C125994
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    (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-heshow more
    SMILES
    CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1
    InChIKey
    QASFUMOKHFSJGL-LAFRSMQTSA-N
    InChI
    1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17,19-21,23-25,28-29H,6-14H2,1-show more
    Synonyme
    (3beta,22S,23R)-17,23-epoxyveratraman-3-ol | A881419 | HMS3403D13 | GAMMA CYCLODEXTRIN [MART.] | BRD-K58938839-001-03...
  11. SANT-1, Antagonist of SMO
    CAS: 304909-07-7 Summenformel: C23H27N5 Molekulargewicht: 373.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S129830
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    (E)-N-(4-benzylpiperazin-1-yl)-1-(3,5-dimethyl-1-phenylpyrazol-4-yl)methanimine
    SMILES
    CC1=C(C(=NN1C2=CC=CC=C2)C)C=NN3CCN(CC3)CC4=CC=CC=C4
    InChIKey
    FOORCIAZMIWALX-JJIBRWJFSA-N
    InChI
    1S/C23H27N5/c1-19-23(20(2)28(25-19)22-11-7-4-8-12-22)17-24-27-15-13-26(14-16-27)18-21-9-5-3-6-10-21/h3-12,17H,13-16,18H2,1-2H3/b24-17+
    Synonyme
    EX-A1250 | HMS3412P14 | NCGC00092291-01 | QUIRAL TADEODAL | SANT-1 | SCHEMBL10063651 | (E)-4-Benzyl-N-((3,5-dimethyl-...
  12. SANT-2, Antagonist of SMO
    CAS: 329196-48-7 PubChem CID: 1367095 Summenformel: C26H26ClN3O4 Molekulargewicht: 479.96
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S275667
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    N-[3-(1H-benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
    SMILES
    CCOC1=CC(=CC(=C1OCC)OCC)C(=O)NC2=CC(=C(C=C2)Cl)C3=NC4=CC=CC=C4N3
    InChIKey
    VQOJFGFKIVFMDH-UHFFFAOYSA-N
    InChI
    1S/C26H26ClN3O4/c1-4-32-22-13-16(14-23(33-5-2)24(22)34-6-3)26(31)28-17-11-12-19(27)18(15-17)25-29-20-9-7-8-10-21(20)30-25/h7-15H,4-6H2,1-3H3,(H,28,31)show more
    Synonyme
    GTPL10331 | J-018936 | HY-107408 | SR-01000419345 | NCGC00263210-04 | BDBM50249489 | HMS3414C13 | NCGC00263210-06 | S...
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What can I find under Hedgehog?
This listing collects compounds associated with Hedgehog within our Stem Cell/Wnt area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Hedgehog?
Consider the reported potency of each Hedgehog compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Hedgehog compounds?
Each Hedgehog product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Hedgehog compounds by activity or structure?
Yes. Filter the Hedgehog listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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