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  1. Lumiflavine
    CAS: 1088-56-8 EG-Nummer: 214-125-5 Summenformel: C13H12N4O2 Molekulargewicht: 256.26
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: L338492
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    7,8,10-trimethylbenzo[g]pteridine-2,4-dione
    SMILES
    CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C
    InChIKey
    KPDQZGKJTJRBGU-UHFFFAOYSA-N
    InChI
    1S/C13H12N4O2/c1-6-4-8-9(5-7(6)2)17(3)11-10(14-8)12(18)16-13(19)15-11/h4-5H,1-3H3,(H,16,18,19)
    Synonyme
    7,8,10-trimethyl-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione | 7,8,10-Trimethylbenzo(g)pteridine-2,4,(3H,10H)-dione | BE...
  2. RO4929097, Gamma-secretase inhibitor
    CAS: 847925-91-1 PubChem CID: 49867930 Summenformel: C22H20F5N3O3 Molekulargewicht: 469.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: R127403
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    2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide
    SMILES
    CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O
    InChIKey
    OJPLJFIFUQPSJR-INIZCTEOSA-N
    InChI
    1S/C22H20F5N3O3/c1-20(2,18(32)28-11-21(23,24)22(25,26)27)19(33)30-16-14-9-4-3-7-12(14)13-8-5-6-10-15(13)29-17(16)31/h3-10,16H,11H2,1-2H3,(H,28,32)(H,2show more
    Synonyme
    NCGC00263162-01 | Propanediamide, N-((7S)-6,7-dihydro-6-oxo-5H-dibenz(b,d)azepin-7-yl)-2,2-dimethyl-N'-(2,2,3,3,3-pen...
  3. Procyanidin B2 3,3′-di-O-gallate
    CAS: 79907-44-1 PubChem CID: 124016 Summenformel: C44H34O20 Molekulargewicht: 882.73
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: P350101
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    [(2R,3R)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-4-yl]-5,7-dshow more
    SMILES
    C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)OC(=O)C6=CC(=C(C(=C6)O)O)O)O)O)C7=CC(=C(C=C7)O)O)OC(=O)C8=CC(=C(C(=C8)O)O)O
    InChIKey
    KTLUHRSHFRODPS-RIQPQZJCSA-N
    InChI
    1S/C44H34O20/c45-19-11-26(51)34-32(12-19)61-40(16-2-4-22(47)25(50)6-16)42(64-44(60)18-9-30(55)38(58)31(56)10-18)36(34)35-27(52)14-23(48)20-13-33(62-43show more
    Synonyme
    CHEBI:172846 | Procyanidin B2 3,3'-di-O-gallate | 3,3'-Digalloylprocyanidin B2 | Proanthocyanidin B2 3,3'-O-gallate |...
  4. Carvacrol, Channel blocker of TRPM7;Activator of TRPV3
    CAS: 499-75-2 EG-Nummer: 207-889-6 Summenformel: C10H14O Molekulargewicht: 150.22
    Flüssigkeit Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: C107162
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    2-methyl-5-propan-2-ylphenol
    SMILES
    CC1=C(C=C(C=C1)C(C)C)O
    InChIKey
    RECUKUPTGUEGMW-UHFFFAOYSA-N
    InChI
    1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3
    Synonyme
    2-methyl-5-propan-2-ylphenol | 2-methyl-5-propan-2-yl-phenol | AKOS000120828 | F8889-1978 | MB00118 | Oxycymol | 9B1J...
  5. Valproic acid, Inhibitor of histone deacetylase 1
    CAS: 99-66-1 EG-Nummer: 202-777-3 PubChem CID: 3121 Summenformel: C8H16O2 Molekulargewicht: 144.21
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: V298968
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    2-propylpentanoic acid
    SMILES
    CCCC(CCC)C(=O)O
    InChIKey
    NIJJYAXOARWZEE-UHFFFAOYSA-N
    InChI
    1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
    Synonyme
    Depakene | Depakin chrono | EC 202-777-3 | VALPROIC ACID | VALPROIC ACID [EP MONOGRAPH] | (n-C3H7)2CHCOOH | Nu-Valpro...
  6. LY-411575
    CAS: 209984-57-6 Summenformel: C26H23F2N3O4 Molekulargewicht: 479.48
    Feststoff ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: L125846
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    (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide
    SMILES
    CC(C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)C(C4=CC(=CC(=C4)F)F)O
    InChIKey
    ULSSJYNJIZWPSB-CVRXJBIPSA-N
    InChI
    1S/C26H23F2N3O4/c1-14(29-25(34)23(32)15-11-16(27)13-17(28)12-15)24(33)30-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)31(2)26(22)35/h3-14,22-23,32H,1-2H3,(H,show more
    Synonyme
    AC-32717 | LY 411,575 | N(2)-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibe...
  7. YO-01027
    CAS: 209984-56-5 PubChem CID: 11454028 Summenformel: C26H23F2N3O3 Molekulargewicht: 463.48
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: Y129283
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    (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide
    SMILES
    CC(C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F
    InChIKey
    QSHGISMANBKLQL-OWJWWREXSA-N
    InChI
    1S/C26H23F2N3O3/c1-15(29-23(32)13-16-11-17(27)14-18(28)12-16)25(33)30-24-21-9-4-3-7-19(21)20-8-5-6-10-22(20)31(2)26(24)34/h3-12,14-15,24H,13H2,1-2H3,(show more
    Synonyme
    Dibenzazepine (Deshydroxy LY 411575) | NCGC00263188-03 | SB47619 | SCHEMBL3046688 | C26H23F2N3O3 | SW219340-1 | EX-A0...
  8. Psoralidin
    CAS: 18642-23-4 PubChem CID: 5281806 Summenformel: C20H16O5 Molekulargewicht: 336.34
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: P168140
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    3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one
    SMILES
    CC(=CCC1=CC2=C(C=C1O)OC(=O)C3=C2OC4=C3C=CC(=C4)O)C
    InChIKey
    YABIJLLNNFURIJ-UHFFFAOYSA-N
    InChI
    1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3,5-9,21-22H,4H2,1-2H3
    Synonyme
    3,9-dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c][1]benzopyran-6-one | UNII-G16ZUQ069L | BDBM246524 | HY...
  9. DAPT
    CAS: 208255-80-5 Summenformel: C23H26F2N2O4 Molekulargewicht: 432.46
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: D126677
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    tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
    SMILES
    CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F
    InChIKey
    DWJXYEABWRJFSP-XOBRGWDASA-N
    InChI
    1S/C23H26F2N2O4/c1-14(26-19(28)12-15-10-17(24)13-18(25)11-15)21(29)27-20(16-8-6-5-7-9-16)22(30)31-23(2,3)4/h5-11,13-14,20H,12H2,1-4H3,(H,26,28)(H,27,2show more
    Synonyme
    Glycine, N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)- | MRF-0000012 | (S)-tert...
  10. FLI-06
    CAS: 313967-18-9 EG-Nummer: 887-718-5 Summenformel: C25H30N2O5 Molekulargewicht: 438.52
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: F275654
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    cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate
    SMILES
    CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4
    InChIKey
    SWWVFYHSSOWZMF-UHFFFAOYSA-N
    InChI
    1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2,3)14-20(23)28/h9-12,18,22,26H,4-8,13-14H2,1-3H3
    Synonyme
    Cyclohexyl2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,8-tetrahydrochinolin-3-carboxylat
  11. Prednisone 21-acetate
    CAS: 125-10-0 PubChem CID: 91438 Summenformel: C23H28O6 Molekulargewicht: 400.46
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: P302294
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    [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
    SMILES
    CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)C=CC34C)C)O
    InChIKey
    MOVRKLZUVNCBIP-RFZYENFJSA-N
    InChI
    1S/C23H28O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h6,8,10,16-17,20,28H,4-5,7,9,11-12H2,1-3H3/t16-show more
    Synonyme
    17-Hydroxy-3,11,20-trioxopregna-1,4-dien-21-yl acetate, (17.alpha.)- # | 4-08-00-03532 (Beilstein Handbook Reference)...
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Häufig gestellte Fragen

How is the Notch listing put together?
It draws on reported Notch annotations within Stem Cell/Wnt and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Notch modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Notch entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Notch compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Notch work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Notch compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Notch compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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