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  1. Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitor
    CAS: 111358-88-4 Summenformel: C26H21N3O4 Molekulargewicht: 439.46
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: L275009
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    (15S,16S,18R)-16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,1show more
    SMILES
    CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
    InChIKey
    UIARLYUEJFELEN-LROUJFHJSA-N
    InChI
    1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12Hshow more
    Synonyme
    SPM-924 | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanod...
  2. ZM 449829
    CAS: 4452-06-6 PubChem CID: 3799 Summenformel: C13H10O Molekulargewicht: 182.22
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: Z275707
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    1-naphthalen-2-ylprop-2-en-1-one
    SMILES
    C=CC(=O)C1=CC2=CC=CC=C2C=C1
    InChIKey
    FOTCGZPFSUWZBN-UHFFFAOYSA-N
    InChI
    1S/C13H10O/c1-2-13(14)12-8-7-10-5-3-4-6-11(10)9-12/h2-9H,1H2
    Synonyme
    1-(2-Naphthalenyl)-2-propen-1-one
  3. ZM 39923 HCl
    CAS: 1021868-92-7 Summenformel: C23H25NO.HCl Molekulargewicht: 367.91
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: Z129618
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    3-[benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one;hydrochloride
    SMILES
    CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3.Cl
    InChIKey
    NJTUORMLOPXPBY-UHFFFAOYSA-N
    InChI
    1S/C23H25NO.ClH/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22;/h3-13,16,18H,14-15,17H2,1-2H3;1H
    Synonyme
    DTXSID301017077 | 3-BENZYLISOPROPYLAMINO-1-NAPHTHALEN-2-YL-PROPAN-1-ONE HYDROCHLORIDE | ZM39923 HCl;ZM-39923 HCl | 3-...
  4. Curculigoside
    CAS: 85643-19-2 Summenformel: C22H26O11 Molekulargewicht: 466.44
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: C399228
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    [5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl 2,6-dimethoxybenzoate
    SMILES
    COC1=C(C(=CC=C1)OC)C(=O)OCC2=C(C=CC(=C2)O)OC3C(C(C(C(O3)CO)O)O)O
    InChIKey
    SJJRKHVKAXVFJQ-QKYBYQKWSA-N
    InChI
    1S/C22H26O11/c1-29-14-4-3-5-15(30-2)17(14)21(28)31-10-11-8-12(24)6-7-13(11)32-22-20(27)19(26)18(25)16(9-23)33-22/h3-8,16,18-20,22-27H,9-10H2,1-2H3/t16show more
    Synonyme
    [5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl2,6-dimethoxybenzoate | A6...
  5. Swertiamarine
    CAS: 17388-39-5 PubChem CID: 442435 Summenformel: C16H22O10 Molekulargewicht: 374.34
    Feststoff Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S110090
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    (3S,4R,4aR)-4-ethenyl-4a-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,5,6-tetrahydropyrano[3,4-c]pyran-8-one
    SMILES
    C=CC1C(OC=C2C1(CCOC2=O)O)OC3C(C(C(C(O3)CO)O)O)O
    InChIKey
    HEYZWPRKKUGDCR-QBXMEVCASA-N
    InChI
    1S/C16H22O10/c1-2-7-14(24-6-8-13(21)23-4-3-16(7,8)22)26-15-12(20)11(19)10(18)9(5-17)25-15/h2,6-7,9-12,14-15,17-20,22H,1,3-5H2/t7-,9+,10+,11-,12+,14-,1show more
    Synonyme
    A811580 | Swertiamarin, >=95% (LC/MS-ELSD) | 1H,3H-Pyrano(3,4-c)pyran-1-one, 5-ethenyl-6-(beta-D-glucopyranosyloxy)-4...
  6. Atractylenolide I
    CAS: 73069-13-3 Summenformel: C15H18O2 Molekulargewicht: 230.3
    Feststoff Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: A304497
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    (4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8-tetrahydro-4H-benzo[f][1]benzofuran-2-one
    SMILES
    CC1=C2CC3C(=C)CCCC3(C=C2OC1=O)C
    InChIKey
    ZTVSGQPHMUYCRS-SWLSCSKDSA-N
    InChI
    1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1
    Synonyme
    HMS3886N08 | Atractylenolide I | Atractylenolide I, >=98% (HPLC) | s8291 | (4aS,8aS)-3,8a-dimethyl-5-methylene-4a,5,6...
  7. Ruxolitinib phosphate salt, Tyrosine-protein kinase JAK2 inhibitor
    CAS: 1092939-17-7 EG-Nummer: 641-390-8 PubChem CID: 25127112 Summenformel: C17H21N6O4P Molekulargewicht: 404.4
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: R171967
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    (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
    SMILES
    C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
    InChIKey
    JFMWPOCYMYGEDM-XFULWGLBSA-N
    InChI
    1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;show more
    Synonyme
    (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrilephosphate | Jakavi (TN) | (3R)...
  8. LFM-A13
    CAS: 62004-35-7 EG-Nummer: 835-258-0 Summenformel: C11H8Br2N2O2 Molekulargewicht: 360
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: L286934
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    2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
    SMILES
    CC(=C(C#N)C(=O)NC1=C(C=CC(=C1)Br)Br)O
    InChIKey
    UVSVTDVJQAJIFG-UHFFFAOYSA-N
    InChI
    1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)
    Synonyme
    AKOS028108222 | alpha-Cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide | KBio3_001038 | HMS3370M16 | L...
  9. LY2784544, Tyrosine-protein kinase JAK2 inhibitor
    CAS: 1229236-86-5 Summenformel: C23H25ClFN7O Molekulargewicht: 469.95
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: L126490
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    3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine
    SMILES
    CC1=CC(=NN1)NC2=NN3C(=C(N=C3C(=C2)CN4CCOCC4)C)CC5=C(C=C(C=C5)Cl)F
    InChIKey
    SQSZANZGUXWJEA-UHFFFAOYSA-N
    InChI
    1S/C23H25ClFN7O/c1-14-9-21(29-28-14)27-22-11-17(13-31-5-7-33-8-6-31)23-26-15(2)20(32(23)30-22)10-16-3-4-18(24)12-19(16)25/h3-4,9,11-12H,5-8,10,13H2,1-show more
    Synonyme
    C23H25ClFN7O | 3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpholinomethyl)imidazo[1,2-b]py...
  10. WHI-P131 hydrochloride
    CAS: 188829-39-2 PubChem CID: 22022153 Summenformel: C16H16ClN3O3 Molekulargewicht: 333.77
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: W274689
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    4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol;hydrochloride
    SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC.Cl
    InChIKey
    HNJNNCPPISFBGR-UHFFFAOYSA-N
    InChI
    1S/C16H15N3O3.ClH/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10;/h3-9,20H,1-2H3,(H,17,18,19);1H
    Synonyme
    4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenolhydrochloride
  11. WHI-P154, Inhibitor of epidermal growth factor receptor;Inhibitor of Janus kinase 1;Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3
    CAS: 211555-04-3 EG-Nummer: 809-014-9 PubChem CID: 3795 Summenformel: C16H14BrN3O3 Molekulargewicht: 376.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: W125072
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    2-bromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
    SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC
    InChIKey
    CBIAKDAYHRWZCU-UHFFFAOYSA-N
    InChI
    1S/C16H14BrN3O3/c1-22-14-6-10-12(7-15(14)23-2)18-8-19-16(10)20-9-3-4-13(21)11(17)5-9/h3-8,21H,1-2H3,(H,18,19,20)
    Synonyme
    HB1431 | BCP09619 | SR-02000000171 | 4-(3'-bromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline | GTPL5993 | 2-Bromo...
  12. WHI-P97
    CAS: 211555-05-4 PubChem CID: 3796 Summenformel: C16H13Br2N3O3 Molekulargewicht: 455.11
    Feststoff ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: W125855
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    2,6-dibromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
    SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C(=C3)Br)O)Br)OC
    InChIKey
    YVCXQRVVNQMZEI-UHFFFAOYSA-N
    InChI
    1S/C16H13Br2N3O3/c1-23-13-5-9-12(6-14(13)24-2)19-7-20-16(9)21-8-3-10(17)15(22)11(18)4-8/h3-7,22H,1-2H3,(H,19,20,21)
    Synonyme
    HMS3265F24 | 2,6-Dibromo-4-((6,7-dimethoxyquinazolin-4-yl)amino)phenol | 2,6-Dibromo-4-(6,7-dimethoxy-quinazolin-4-yl...
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Häufig gestellte Fragen

How is the JAK listing put together?
It draws on reported JAK annotations within Stem Cell/Wnt and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a JAK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the JAK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for JAK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For JAK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the JAK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of JAK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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