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Serplulimab (anti-PDCD1) - Primary antibody, specific to PDCD1, >95%, Human IgG4SP, ANTAGONIST of Programmed cell death protein 1 antagonist, ANTAGONIST of Programmed cell death protein 1 antagonist

CAS: 2231029-82-4 Cat. No.: Ab176173
COA
Serplulimab (anti-PDCD1) - >95% by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human
Isotype
Human IgG4SP
Conjugation
Unconjugated
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100μg
Ab176173-100μg
10
$65.90
1mg
Ab176173-1mg
4
$325.90
5mg
Ab176173-5mg
1
$941.90
10mg
Ab176173-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$1,505.90
Enter a quantity for the sizes you want to add.
Bulk / Custom
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Storage and Shipping Images Documentation Advanced Data Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Solution Calculators Reviews
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Serplulimab (anti-PDCD1) is humanized monoclonal anti-PD-1 antibody. Serplulimab (anti-PDCD1) can be used in research of small cell lung cancer.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Serplulimab (anti-PDCD1) - Primary antibody, specific to PDCD1, >95%, Human IgG4SP, ANTAGONIST of Programmed cell death protein 1 antagonist
Synonyms
CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 antibody | PD-1 antibody | PD1 antibody | PDCD 1 antibody | PDCD1 antibody | PDCD1_HUMAN antibody | Programmed cell death 1 antibody | Progr
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species
Human
Specificity
PDCD1
Conjugation
Unconjugated
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
ANTAGONIST
Mechanism of action
ANTAGONIST of Programmed cell death protein 1 antagonist
Isotype
Human IgG4SP
Light Chain Type
kappa
SDS-PAGE
27.1 kDa (Light Chain) & 51.9 kDa (Heavy Chain), under reducing conditions; 180.9 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Purity
>95%
Concentration
See COA
CAS
2231029-82-4
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Serplulimab (anti-PDCD1) (Ab176173) - SEC
The purity of Serplulimab (anti-PDCD1) (Ab176173) is more than 95% verified by HPLC.

Serplulimab (anti-PDCD1) (Ab176173) - Flow Cytometry
Flow Cytometry analysis of 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated Jurkat cells (24h) labelling PDCD1 (red) with Serplulimab (anti-PDCD1) (Ab176173). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Serplulimab (anti-PDCD1) (Ab176173) - ELISA
Immobilized Recombinant Human PD-1 Protein (rp176241) at 2.0 μg/mL can bind Serplulimab (anti-PDCD1) (Ab176173) with the EC₅₀ of 59.84 ng/mL.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
PDCD1 Tclin Programmed cell death protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDCD1 Tclin Programmed cell death protein 1 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202871Certificate of AnalysisFeb 23, 2024 Ab176173
ZJ24F0202870Certificate of AnalysisFeb 23, 2024 Ab176173
ZJ24F0202869Certificate of AnalysisFeb 23, 2024 Ab176173
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →
Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

View related series

Click to view target information: PDCD1
 Accession#:Q15116 (39) Gene ID:5133 (39) PD1 (37) PDCD1 (40)

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