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SPT Imidazopyridine 1 - ≥98% , CAS No.1933533-18-6

SPT Imidazopyridine 1 - ≥98% , CAS No.1933533-18-6

CAS: 1933533-18-6 Cat. No.: S288862 Molecular Weight: 364.44 PubChem CID: 131954583

COA

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SPT Imidazopyridine 1 - ≥98% CAS No(1933533-18-6) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY ≥98%

Synonyms

4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid | SPT-IN-1 | Imidazopyridine 1 | SPT Inhibitor 1 | SPT IN 1

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview Specifications Names and Identifiers Documentation Advanced Data 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product description：

Potent serine palmitoyl transferase inhibitor

Specifications

Synonyms

4-[6-(1-Oxoheptyl)imidazo[1, 2-a]pyridin-8-yl]benzeneacetic acid | SPT-IN-1 | Imidazopyridine 1 | SPT Inhibitor 1 | SPT IN 1

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Potent serine palmitoyl transferase (SPT) inhibitor (IC50= 5 nM). Dose-dependently inhibits incorporation of14C-serine into ceramide. Reduces plasma ceramide levelsin vivo. Also increases plasma HDL and reduces vLDL cholesterol levels in rats.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

Canonical Smiles	CCCCCCC(=O)C1=CN2C=CN=C2C(=C1)C3=CC=C(C=C3)CC(=O)O
IUPAC Name	2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid
InChIKey	MMYRYMMKMUTPBB-UHFFFAOYSA-N
INCHI	1S/C22H24N2O3/c1-2-3-4-5-6-20(25)18-14-19(22-23-11-12-24(22)15-18)17-9-7-16(8-10-17)13-21(26)27/h7-12,14-15H,2-6,13H2,1H3,(H,26,27)
Isomeric SMILES	CCCCCCC(=O)C1=CN2C=CN=C2C(=C1)C3=CC=C(C=C3)CC(=O)O
PubChem CID	131954583
Molecular Weight	364.44

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure

Associated Targets(Human)

SPTLC1 Tchem Serine palmitoyltransferase 1 (2 Activities)

Discover Target: SPTLC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Associated Targets(non-human)

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
C2425493	Certificate of Analysis	Mar 11, 2024	S288862
C2425494	Certificate of Analysis	Mar 11, 2024	S288862
C2425495	Certificate of Analysis	Mar 11, 2024	S288862
C2425496	Certificate of Analysis	Mar 11, 2024	S288862
C2425497	Certificate of Analysis	Mar 11, 2024	S288862
C2425505	Certificate of Analysis	Mar 11, 2024	S288862
C2425506	Certificate of Analysis	Mar 11, 2024	S288862
C2425507	Certificate of Analysis	Mar 11, 2024	S288862
C2425508	Certificate of Analysis	Mar 11, 2024	S288862
C2425509	Certificate of Analysis	Mar 11, 2024	S288862

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 36.44, Max Conc. mM: 100
Molecular Weight	364.400 g/mol
XLogP3	5.000
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	9
Exact Mass	364.179 Da
Monoisotopic Mass	364.179 Da
Topological Polar Surface Area	71.700 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	502.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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