Tetramethylrhodamine hyaluronic acid from Streptococcus equi - average mol wt 5000000

Cat. No.: T292214

GRADE & PURITY average mol wt 5000000

Synonyms

T-hyaluronic acid;Tetramethylrhodamine Hyaluronic Acid;Tetramethyl-rhodamine hyaluronic acid Hyaluronan；Tetramethyl-rhodamine B hyaluronan;6´bis(tetramethylamino) -3-oxospiro(isobenzofuran-1(3H),9´-9H]xanthen]-5(or 6)- yl).

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Overview

THA-Se is supplied a red solid which is soluble in water. Tetramethyl-rhodamine hyaluronic acid (THA-Se) has similar applications to those described for fluorescein hyaluronic acid (see FHA-Se) but has certain advantages. As mentioned earlier, the fluorescence of tetramethyl-rhodamine is less dependent on pH than FITClabels. Also, the longer emission wavelength avoids interference from background images in experimental environments. Invasive growth into brain tissue employing TR-HA and 2-photon imaging has been described. Hyaluronic acid (HA) can be obtained from various sources, for example rooster combs or Streptococcus equi. We can supply derivatives of either of these qualities labelled with or with tetramethylrhodamine (T-Ha). All batches are checked for molecular weight, degree of substitution, loss on drying and free TRITC. Hyaluronic acid is a polysaccharide composed of alternating β(1-3) glucuronide and β(1-4) glucosaminide units derived from Streptococcus equi. The hyaluronic acid is labelled with amino-tetramethylrhodamine. The degree of substitution lies between 0.001 and 0.008. The labelling procedures do not lead to depolymerisation of the HA. 

Spectral data

T-Ha has an excitation maximum at 552 nm and an emission maximum at 576 nm.

Application

T-Ha have been used to e.g. investigate invasive growth into brain tissue.

Specifications

Synonyms

T-hyaluronic acid;Tetramethylrhodamine Hyaluronic Acid;Tetramethyl-rhodamine hyaluronic acid Hyaluronan；Tetramethyl-rhodamine B hyaluronan;6´bis(tetramethylamino) -3-oxospiro(isobenzofuran-1(3H), 9´-9H]xanthen]-5(or 6)- yl).

Specifications & Purity

average mol wt 5000000

Storage

Store at -20°C, Argon charged, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Chemical and Physical Properties

• Solubility: dissolves readily in water
• Sensitivity: air sensitive