Thalidomide-O-amido-PEG3-NH2 hydrochloride - ≥95%(HPLC) , CAS No.2245697-84-9

CAS: 2245697-84-9 Cat. No.: T287614 Molecular Weight: 542.97 PubChem CID: 134160246
AVAILABLE TO ORDER
GRADE & PURITY ≥95%(HPLC)
Synonyms
Thalidomide - linker 1 | N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Application
PROTAC
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
T287614-5mg
1

$38.90

$58.90
Save $20.00 (33.96%)
25mg
T287614-25mg
1

$144.90

$217.90
Save $73.00 (33.50%)
100mg
T287614-100mg
1

$403.90

$605.90
Save $202.00 (33.34%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥95%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.


Specifications

Synonyms
Thalidomide - linker 1 | N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]-2-[[2-(2, 6-dioxo-3-piperidinyl)-2, 3-dihydro-1, 3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Specifications & Purity
≥95%(HPLC)
Biochemical and Physiological Mechanisms
Functionalized cereblon ligand for PROTACsup>® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.This product has
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%(HPLC)
Names and Identifiers
Pubchem Sid488202798
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488202798
Canonical SmilesC1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCOCCOCCOCCN.Cl
IUPAC NameN-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;hydrochloride
InChIKeyORRMBTUTYKQYQU-UHFFFAOYSA-N
INCHI1S/C23H30N4O9.ClH/c24-6-8-33-10-12-35-13-11-34-9-7-25-19(29)14-36-17-3-1-2-15-20(17)23(32)27(22(15)31)16-4-5-18(28)26-21(16)30;/h1-3,16H,4-14,24H2,(H,25,29)(H,26,28,30);1H
PubChem CID 134160246
Molecular Weight 542.97

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
D2313564Certificate of AnalysisJan 21, 2026 T287614
D2313571Certificate of AnalysisJan 21, 2026 T287614
D2313572Certificate of AnalysisJan 21, 2026 T287614
D2313575Certificate of AnalysisJan 21, 2026 T287614
D2313578Certificate of AnalysisJan 21, 2026 T287614
D2313580Certificate of AnalysisJan 21, 2026 T287614
Chemical and Physical Properties
SensitivityMoisture sensitive.
Molecular Weight543.000 g/mol
XLogP3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count15
Exact Mass542.178 Da
Monoisotopic Mass542.178 Da
Topological Polar Surface Area176.000 Ų
Heavy Atom Count37
Formal Charge0
Complexity808.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.