Tifcemalimab (anti-BTLA) - Primärer Antikörper, specific to BTLA, Human IgG4SP

Cat. No.: Ab182990
Zu bestellen verfügbar
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Mensch
Reactive species
Mensch
Isotype
Human IgG4SP
Conjugation
Unconjugated
Size
Deutschland (EU)
USA*
Price
Qty
100μg
Ab182990-100μg
5 Auf Lager
100,57€
1mg
Ab182990-1mg
2 Auf Lager
496,26€
5mg
Ab182990-5mg
1 Auf Lager
1.287,64€
10mg
Ab182990-10mg
Auf Bestellung · 8–12 Wochen
2.061,66€
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Tifcemalimab (anti-BTLA) is a humanized anti-BTLA (B and T lymphocyte attenuation factor) monoclonal antibody. Tifcemalimab (anti-BTLA) blocks the interaction of HVEM-BTLA by binding to BTLA, and thus blocks the inhibitory signaling pathway mediated by BTLA. Tifcemalimab (anti-BTLA) can be used in research of cancer.

Specifications

Product Name
Tifcemalimab (anti-BTLA) - Primärer Antikörper, specific to BTLA, Human IgG4SP
Synonyme
B and T lymphocyte attenuator antibody | B and T lymphocyte associated protein antibody | B and T lymphocyte associated antibody | B- and T-lymphocyte attenuator antibody | B- and T-lymphocyte-associated protein antibody | JS004 | MGC129743 | BTLA antibod
Spezifikationen & Reinheit
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemische und physiologische Mechanismen
Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. Post-translational: Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11. N-glycosylated.
Wirtsspezies
Mensch
Spezifität
BTLA
Konjugation
Unconjugated
Note
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Isotyp
Human IgG4SP
Lichterketten-Typ
kappa
SDS-PAGE
146 kDa
Verfahren zur Reinigung
Protein A purified
Konzentration
See COA
Lagerung und Versand
Storage
Store at -80°C,Avoid repeated freezing and thawing
Verschickt in
Dry ice packs + Cold packs
Stabilität und Lagerung
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Bilder

Tifcemalimab (anti-BTLA) (Ab182990) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling BTLA with Tifcemalimab (anti-BTLA) (Ab182990) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Tifcemalimab (anti-BTLA) (Ab182990) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling BTLA (red) with Tifcemalimab (anti-BTLA) (Ab182990) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Tifcemalimab (anti-BTLA) (Ab182990) - ELISA
Immobilized Recombinant Human BTLA protein (rp143904) at 1.0 μg/mL can bind Tifcemalimab (anti-BTLA) (Ab182990) with the EC₅₀ of 130.30 ng/mL.

Tifcemalimab (anti-BTLA) (Ab182990) - SEC
The purity of Tifcemalimab (anti-BTLA) (Ab182990) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Zugehörige Ziele (menschlich)
BTLA Tbio B- and T-lymphocyte attenuator (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDatumArtikel
ZJ24F1113374Certificate of AnalysisAug 06, 2026 Ab182990
ZJ24F1113375Certificate of AnalysisAug 06, 2026 Ab182990
ZJ24F1113376Certificate of AnalysisAug 06, 2026 Ab182990
Lösungsrechner
Bewertungen

Kundenbewertungen

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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