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emzeltrectinib - Moligand™ , Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3, CAS No.2223678-97-3, Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3

CAS: 2223678-97-3 Cat. No.: E610115 PubChem CID: 134480550
COA
emzeltrectinib - Moligand™ , Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3, CAS No.2223678-97-3, Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
Synonyms
GLXC-26845 | GTPL12377 | emzeltrectinib [INN] | 436Z4BZ8HF | SCHEMBL20119394 | 2223678-97-3 | Emzeltrectinib | Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-5-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoro-1-pyrrolidinyl]- | 2-Amino-5-[(2R,4S)-2-(2,5-difluor
Storage
Room temperature
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
E610115-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$799.90
25mg
E610115-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,230.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Names and Identifiers Documentation Advanced Data 3D Structure Associated Targets(Human) Certificates（CoA,COO,BSE/TSE and Analysis Chart) Solution Calculators Reviews
🧪

Why this grade

Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
GLXC-26845 | GTPL12377 | emzeltrectinib [INN] | 436Z4BZ8HF | SCHEMBL20119394 | 2223678-97-3 | Emzeltrectinib | Pyrazolo[1, 5-a]pyrimidine-3-carboxamide, 2-amino-5-[(2R, 4S)-2-(2, 5-difluorophenyl)-4-fluoro-1-pyrrolidinyl]- | 2-Amino-5-[(2R, 4S)-2-(2, 5-difluor
Specifications & Purity
Moligand™
Storage
Room temperature
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3
Names and Identifiers
Canonical SmilesC1[C@@H](CN([C@H]1c1c(ccc(c1)F)F)c1nc2c(c(nn2cc1)N)C(=O)N)F
IUPAC Name2-amino-5-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChIKeyYFTARXQOKASKBW-JOYOIKCWSA-N
INCHI1S/C17H15F3N6O/c18-8-1-2-11(20)10(5-8)12-6-9(19)7-25(12)13-3-4-26-17(23-13)14(16(22)27)15(21)24-26/h1-5,9,12H,6-7H2,(H2,21,24)(H2,22,27)/t9-,12+/m0/s1
Isomeric SMILES C1[C@@H](CN([C@H]1C2=C(C=CC(=C2)F)F)C3=NC4=C(C(=NN4C=C3)N)C(=O)N)F
PubChem CID 134480550

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NTRK2 Tclin BDNF/NT-3 growth factors receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NTRK1 Tclin High affinity nerve growth factor receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NTRK3 Tclin NT-3 growth factor receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
JAK2 Tclin Tyrosine-protein kinase JAK2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews

Customer Reviews

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