DNA Alkylator/Crosslinker

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  1. Iodoacetamide
    CAS: 144-48-9 EC Number: 205-630-1 Formula: C2H4INO Molecular Weight: 184.96
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Ultra pure ? Ultra-pure grade with very low impurity content across the board. Use for trace analysis, electronics, or processes intolerant of contamination. ≥99%(NMR)
    ● In Stock — US warehouse, ships to EU* Item #: I131590
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    Technical Identifiers
    IUPAC Name
    2-iodoacetamide
    SMILES
    C(C(=O)N)I
    InChIKey
    PGLTVOMIXTUURA-UHFFFAOYSA-N
    InChI
    1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
    Synonyms
    A808220 | Iodoacetamide, >=98.0% (AT), purum | Iodoacetamide, Single use vial of 56 mg | SCHEMBL20371 | 1219802-64-8 ...
  2. Lomustine, DNA inhibitor
    CAS: 13010-47-4 EC Number: 235-859-2 Formula: C9H16ClN3O2 Molecular Weight: 233.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: L123247
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    IUPAC Name
    1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
    SMILES
    C1CCC(CC1)NC(=O)N(CCCl)N=O
    InChIKey
    GQYIWUVLTXOXAJ-UHFFFAOYSA-N
    InChI
    1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
    Synonyms
    3-(2-chloroethyl)-1-cyclohexyl-3-nitrosourea | NCGC00167466-01 | Prava | SCHEMBL3995 | C07079 | LOMUSTINE [HSDB] | N-...
  3. Busulfan
    CAS: 55-98-1 EC Number: 200-250-2 Formula: C6H14O6S2 Molecular Weight: 246.3
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: B123234
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    IUPAC Name
    4-methylsulfonyloxybutyl methanesulfonate
    SMILES
    CS(=O)(=O)OCCCCOS(=O)(=O)C
    InChIKey
    COVZYZSDYWQREU-UHFFFAOYSA-N
    InChI
    1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3
    Synonyms
    DTXSID3020910 | 2041 C. B. | BUSULFAN [VANDF] | Mielosan | Tetramethylene {bis[methanesulfonate]} | TETRAMETHYLENE DI...
  4. Nitrilotri(methylphosphonic acid)(ATMP)
    CAS: 6419-19-8 EC Number: 229-146-5 Formula: C3H12NO9P3 Molecular Weight: 299.05
    Liquid 50% in water
    ● In Stock — US warehouse, ships to EU* Item #: N115347
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    IUPAC Name
    [bis(phosphonomethyl)amino]methylphosphonic acid
    SMILES
    C(N(CP(=O)(O)O)CP(=O)(O)O)P(=O)(O)O
    InChIKey
    YDONNITUKPKTIG-UHFFFAOYSA-N
    InChI
    1S/C3H12NO9P3/c5-14(6,7)1-4(2-15(8,9)10)3-16(11,12)13/h1-3H2,(H2,5,6,7)(H2,8,9,10)(H2,11,12,13)
    Synonyms
    ATMP | 7611-50-9 (tri-hydrochloride salt) | Aminotris(methanephosphonic acid) | Phosphonic acid, (nitrilotris(methyle...
  5. N,N-Bis(2-chloroethyl)phosphorodiamidic Acid Cyclohexylamine Salt
    CAS: 1566-15-0 Formula: C10H24Cl2N3O2P Molecular Weight: 320.2
    ◐ .Made to order · 8–12 wks Item #: N358080
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    IUPAC Name
    amino-[bis(2-chloroethyl)amino]phosphinic acid;cyclohexanamine
    SMILES
    C1CCC(CC1)N.C(CCl)N(CCCl)P(=O)(N)O
    InChIKey
    BGTIPRUDEMNRIP-UHFFFAOYSA-N
    InChI
    1S/C6H13N.C4H11Cl2N2O2P/c7-6-4-2-1-3-5-6;5-1-3-8(4-2-6)11(7,9)10/h6H,1-5,7H2;1-4H2,(H3,7,9,10)
    Synonyms
    methyl 1-BOC-2-aziridinecarboxylate | NCI69945 | DTXSID20935481 | OMF 59 | amino-[bis(2-chloroethyl)amino]phosphinic ...
  6. N-Nitroso-N-methylurea
    CAS: 684-93-5 EC Number: 211-678-4 Formula: C2H5N3O2 Molecular Weight: 103.08
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% contain Sulfuric acid as stabilizer
    ● In Stock — US warehouse, ships to EU* Item #: N136701
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    IUPAC Name
    1-methyl-1-nitrosourea
    SMILES
    CN(C(=O)N)N=O
    InChIKey
    ZRKWMRDKSOPRRS-UHFFFAOYSA-N
    InChI
    1S/C2H5N3O2/c1-5(4-7)2(3)6/h1H3,(H2,3,6)
    Synonyms
    Methylnitrosourea | 1-Methyl-1-nitrosourea | N-Methyl-N-nitrosourea
  7. N-Butyl-N-(4-hydroxybutyl)nitrosamine
    CAS: 3817-11-6 Formula: C8H18N2O2 Molecular Weight: 174.24
    ● In Stock — US warehouse, ships to EU* Item #: N159735
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    IUPAC Name
    N-butyl-N-(4-hydroxybutyl)nitrous amide
    SMILES
    CCCCN(CCCCO)N=O
    InChIKey
    DIKPQFXYECAYPC-UHFFFAOYSA-N
    InChI
    1S/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3
    Synonyms
    B0938 | N-Butyl-N-butan-4-ol-nitrosamine | N-Nitroso-N-butyl-N-(4-carboxypropyl)amine | CHEBI:91275 | DTXCID40210 | N...
  8. Carmustine, RNA inhibitor
    CAS: 154-93-8 EC Number: 205-838-2 Formula: C5H9Cl2N3O2 Molecular Weight: 214.05
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C132260
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    IUPAC Name
    1,3-bis(2-chloroethyl)-1-nitrosourea
    SMILES
    C(CCl)NC(=O)N(CCCl)N=O
    InChIKey
    DLGOEMSEDOSKAD-UHFFFAOYSA-N
    InChI
    1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
    Synonyms
    FIVB | Spectrum4_000888 | SK-27702 | Bis(chloroethyl)nitrosourea | Bis-N,N'-(chloroethyl)nitrosourea | CCRIS 810 | SR...
  9. Heptaplatin (SKI-2053R)
    CAS: 146665-77-2 Formula: C11H20N2O6Pt Molecular Weight: 473.39
    ● In Stock — US warehouse, ships to EU* Item #: H275271
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    Technical Identifiers
    Synonyms
    [SP-4-2-[4R-(2α,4α,5β)]]-[2-(1-Methylethyl)-1,3-dioxolane-4,5-dimethanamine-N,N'][propanedioato(2-)-O,O']platinum
  10. Carboplatin
    CAS: 41575-94-4 EC Number: 255-446-0 Formula: C6H12N2O4Pt Molecular Weight: 371.25
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C110682
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    IUPAC Name
    azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+)
    SMILES
    C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2]
    InChIKey
    VSRXQHXAPYXROS-UHFFFAOYSA-N
    InChI
    1S/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H2;/q;2*-1;+2
    Synonyms
    cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) | 1,1-Cyclobutanedicarboxylatodiammineplatinum(II)
  11. Iodoacetamide, Activator of TRPA1
    CAS: 144-48-9 EC Number: 205-630-1 Formula: C2H4INO Molecular Weight: 184.96
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: I105563
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    Technical Identifiers
    IUPAC Name
    2-iodoacetamide
    SMILES
    C(C(=O)N)I
    InChIKey
    PGLTVOMIXTUURA-UHFFFAOYSA-N
    InChI
    1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
    Synonyms
    A808220 | Iodoacetamide, >=98.0% (AT), purum | Iodoacetamide, Single use vial of 56 mg | SCHEMBL20371 | 1219802-64-8 ...
  12. PK11000
    CAS: 38275-34-2 PubChem CID: 1241459 Formula: C6H5ClN2O4S Molecular Weight: 236.63
    ● In Stock — US warehouse, ships to EU* Item #: P170046
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    IUPAC Name
    5-chloro-2-methylsulfonylpyrimidine-4-carboxylic acid
    SMILES
    CS(=O)(=O)C1=NC=C(C(=N1)C(=O)O)Cl
    InChIKey
    WZUPWJVRWIVWEF-UHFFFAOYSA-N
    InChI
    1S/C6H5ClN2O4S/c1-14(12,13)6-8-2-3(7)4(9-6)5(10)11/h2H,1H3,(H,10,11)
    Synonyms
    HY-U00447 | SY059860 | BCP30143 | CCG-266846 | EX-A3577 | AKOS000267675 | 5-chloro-2-(methylsulfonyl)-4-Pyrimidinecar...
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for DNA Alkylator/Crosslinker?
Compounds associated with DNA Alkylator/Crosslinker are grouped here under the Cell Cycle/DNA Damage classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does DNA Alkylator/Crosslinker sit within Cell Cycle/DNA Damage?
DNA Alkylator/Crosslinker is one target listing within the Cell Cycle/DNA Damage classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from DNA Alkylator/Crosslinker?
For compounds listed under DNA Alkylator/Crosslinker, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for DNA Alkylator/Crosslinker?
Browse the parent Cell Cycle/DNA Damage listing to reach targets neighbouring DNA Alkylator/Crosslinker, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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