≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Application：
D-Fructose-1,6-bisphosphate (FBP), a common metabolic sugar, is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway. It is an allosteric activator of enzymes such as pyruvate kinase and a substrate used to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1, 6-bisphosphatase(s). FBP is studied as a neuroprotective agent in brain injury.
| Pubchem Sid | 504772830 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772830 |
| Canonical Smiles | C(C(C(C(C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+] |
| IUPAC Name | trisodium;[(2R,3R,4S)-2,3,4-trihydroxy-6-[hydroxy(oxido)phosphoryl]oxy-5-oxohexyl] phosphate;octahydrate |
| InChIKey | BUMXRRGJJDMPRT-PESUWTOCSA-K |
| INCHI | 1S/C6H14O12P2.3Na.8H2O/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16;;;;;;;;;;;/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16);;;;8*1H2/q;3*+1;;;;;;;;/p-3/t3-,5-,6-;;;;;;;;;;;/m1.........../s1 |
| Isomeric SMILES | C([C@H]([C@H]([C@@H](C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+] |
| WGK Germany | 3 |
| PubChem CID | 117072640 |
| Molecular Weight | 550.18 |
| Beilstein | 3837985 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J1826091 | Certificate of Analysis | May 21, 2026 | F111877 |
| L2106577 | Certificate of Analysis | Sep 09, 2025 | F111877 |
| L2106580 | Certificate of Analysis | Sep 09, 2025 | F111877 |
| G2518367 | Certificate of Analysis | Jul 05, 2025 | F111877 |
| G2518368 | Certificate of Analysis | Jul 05, 2025 | F111877 |
| G2518369 | Certificate of Analysis | Jul 05, 2025 | F111877 |
| H1622052 | Certificate of Analysis | Apr 10, 2024 | F111877 |
| B2318784 | Certificate of Analysis | Oct 10, 2022 | F111877 |
| B2318822 | Certificate of Analysis | Oct 10, 2022 | F111877 |
| B2318825 | Certificate of Analysis | Oct 10, 2022 | F111877 |
| B2318834 | Certificate of Analysis | Oct 10, 2022 | F111877 |
| B2318835 | Certificate of Analysis | Oct 10, 2022 | F111877 |
| B2318842 | Certificate of Analysis | Oct 10, 2022 | F111877 |
| B2318870 | Certificate of Analysis | Oct 10, 2022 | F111877 |
| Solubility | Soluble in water |
|---|---|
| Sensitivity | Moisture sensitive |
| 1. Nkoh Jackson Nkoh, He Xian, Lu Hai-long, Li Ke-wei, Shi Ren-yong, Li Jiu-yu, Xu Ren-kou. (2022) Chitosan and D-fructose 1,6-bisphosphate differ in their effects on soil acidity and aluminum activation. JOURNAL OF SOILS AND SEDIMENTS, 22 (8): (2129-2145). [PMID:] [10.1007/s11368-022-03228-6] |
| 2. Mei He, Ma Yange, Wu Huimin, Wang Xuedong. (2021) Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters-Ce(III) fluoroprobe. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 413 (8): (2135-2146). [PMID:33511458] [10.1007/s00216-021-03181-2] |
| 3. Li Zhiyang, Xiao Xilin, Su Changlin, Hu Nan, Nie Changming, Liu Yong, Zhang Di, Wang Zhimei, Liao Lifu. (2019) Synthesis of bipolar tetradentate ligand and determination of fructose 1,6-diphosphate by resonance light scattering of its supramolecular polymer. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 323 (1): (431-438). [PMID:] [10.1007/s10967-019-06947-2] |
| 4. Jinling Cui, Mingzhu Yan, Xiaoyi Liu, Shutao Yin, Shangyun Lu, Lihong Fan, Hongbo Hu. (2019) Inorganic Selenium Induces Nonapoptotic Programmed Cell Death in PC-3 Prostate Cancer Cells Associated with Inhibition of Glycolysis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:31513389] [10.1021/acs.jafc.9b03875] |
| 5. Lian-Hua Fu, Yan-Jun Liu, Ming-Guo Ma, Xue-Ming Zhang, Zhi-Min Xue, Jie-Fang Zhu. (2016) Microwave-Assisted Hydrothermal Synthesis of Cellulose/Hydroxyapatite Nanocomposites. Polymers, 8 (9): (316). [PMID:30974621] [10.3390/polym8090316] |
| 6. Yang Tang, Zheng Wang, Feng Zhou, Ling Li, Chen Sun, Linhui Li, Fei Tang, Dongqin Huang, Zewei Li, Yang Tan, Gang Pei. (2025) Benzoylpaeoniflorin alleviates ulcerative colitis by inhibiting ferroptosis through targeting phosphogluconic dehydrogenase. PHYTOMEDICINE, [PMID:40829505] [10.1016/j.phymed.2025.157111] |
| 7. Zhengxin Mao, Jiachang Shen, Mengxin Liu, Yanjie Ji, Qinhong Wang, Maohua Yang, Jianmin Xing, Yanhe Ma. (2025) Efficient separation of phosphorylated sugars from multi-enzyme system by ultrafiltration and membrane fouling mechanism. CHINESE JOURNAL OF CHEMICAL ENGINEERING, [PMID:] [10.1016/j.cjche.2025.08.003] |
