Dexpramipexole - ≥98% , CAS No.104632-28-2

CAS: 104632-28-2 Cat. No.: D128003 Molecular Weight: 211.33 EC Number: 110-340-2
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
Dexpramipexole [USAN:INN] | UNII-WI638GUS96 | BDBM50568780 | F19514 | DEXPRAMIPEXOLE [USAN] | (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine | (6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine | (R)-PRAMIPEXOLE | SCHEMBL74780 |
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
D128003-10mg
3

$120.90

$172.90
Save $52.00 (30.08%)
50mg
D128003-50mg
3

$302.90

$412.90
Save $110.00 (26.64%)
100mg
D128003-100mg
2

$526.90

$756.90
Save $230.00 (30.39%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist

Specifications

Synonyms
Dexpramipexole [USAN:INN] | UNII-WI638GUS96 | BDBM50568780 | F19514 | DEXPRAMIPEXOLE [USAN] | (6R)-4, 5, 6, 7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine | (6R)-6-N-propyl-4, 5, 6, 7-tetrahydro-1, 3-benzothiazole-2, 6-diamine | (R)-PRAMIPEXOLE | SCHEMBL74780 |
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms

Dexpramipexole, also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. Dexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic later

Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
AGONIST
Purity
≥98%
Names and Identifiers
Pubchem Sid504753701
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504753701
Canonical SmilesCCCNC1CCC2=C(C1)SC(=N2)N
IUPAC Name(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
InChIKeyFASDKYOPVNHBLU-SSDOTTSWSA-N
INCHI1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m1/s1
Isomeric SMILES CCCN[C@@H]1CCC2=C(C1)SC(=N2)N
Molecular Weight 211.33
Reaxy-Rn 6505273
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6505273&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClassOrganonitrogen compounds
SubclassAmines
Intermediate Tree Nodes Not available
Direct ParentAralkylamines
Alternative Parents 2-amino-1,3-thiazoles  Heteroaromatic compounds  Dialkylamines  Azacyclic compounds  Primary amines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Aralkylamine - 1,3-thiazol-2-amine - Heteroaromatic compound - Thiazole - Azole - Azacycle - Organoheterocyclic compound - Secondary amine - Secondary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
DRD3 Tclin D(3) dopamine receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hrh4 Histamine H4 receptor (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
C2111071Certificate of AnalysisJun 09, 2026 D128003
C2111072Certificate of AnalysisJun 09, 2026 D128003
B1526014Certificate of AnalysisApr 15, 2026 D128003
Chemical and Physical Properties
SolubilityDMSO
Molecular Weight211.330 g/mol
XLogP31.900
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass211.114 Da
Monoisotopic Mass211.114 Da
Topological Polar Surface Area79.200 Ų
Heavy Atom Count14
Formal Charge0
Complexity188.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

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