1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
The endoplasmic reticulum maintains protein homeostasis through molecular chaperones, endoplasmic reticulum-associated degradation, and endoplasmic reticulum-selective autophagy. Abnormal proteins that can be unfolded are mainly retrotranslocated through ERAD and degraded by the proteasome, ...
Metabolic disorders involve multiple abnormalities, including insulin resistance, dysregulated glucose and lipid metabolism, chronic inflammation, and oxidative stress. Natural products possess diverse structural classes and molecular targets and can improve metabolic homeostasis by regulating ...
Pyroptosis is a proinflammatory form of regulated cell death mediated by pore formation by Gasdermin family proteins. This process is generally initiated by inflammasome assembly and inflammatory caspase activation, leading to increased plasma membrane permeability, cellular swelling and ...
SARS-CoV-2, human immunodeficiency virus, influenza virus, hepatitis C virus, and hepatitis B virus differ in genome composition, entry pathways, and replication strategies. Interventions targeting receptor binding, membrane fusion, nucleic acid replication, protein processing, genome ...
The English name is p-cymene, and its chemical name is 1-isopropyl-4-methylbenzene. Its molecular formula is C₁₀H₁₄, its relative molecular mass is 134.22, and its CAS number is 99-87-6.
Dyslipidemia is a metabolic condition characterized by abnormal plasma lipid or lipoprotein levels. Persistently elevated LDL-C, triglyceride-rich lipoproteins and their remnants, and lipoprotein(a) [Lp(a)] can all promote atherosclerotic cardiovascular disease. In addition to traditional ...
Formaldehyde can undergo condensation, oxidation, or cyclization reactions with hydrazine derivatives, nitrogen-containing heterocyclic compounds, and aromatic chromogenic reagents to form colored products with characteristic visible-light absorption. Different colorimetric methods vary in ...
Adamantane has the molecular formula C₁₀H₁₆ and consists solely of carbon and hydrogen, without aromatic rings, heteroatoms, or unsaturated bonds. In terms of elemental composition, it is simply a saturated hydrocarbon; nevertheless, adamantane and its derivatives have established ...
Phenol-based nucleic acid extraction separates DNA or RNA from proteins, lipids, and cellular debris through sample lysis, protein denaturation, and aqueous-organic phase partitioning. Neutral or mildly alkaline phenol systems are generally used for DNA and total nucleic acid extraction, whereas ...
