Phenylhydrazine - AR, ≥98% , CAS No.100-63-0

CAS: 100-63-0 Cat. No.: P108563 Molecular Weight: 108.14 Beilstein Registry Number: 606080 EC Number: 202-873-5
AVAILABLE TO ORDER
GRADE & PURITY AR ? Analytical Reagent grade — high-purity chemicals meeting strict assay limits for lab analysis. Use when accuracy matters and trace impurities could skew results. ≥98%
Synonyms
Hydrazinobenzene | Monophenylhydrazine
Storage
Protected from light,Room temperature,Argon charged
Shipped In
FedEx DG Service
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25g
P108563-25g
3
$9.90
100g
P108563-100g
≥10
$22.90
500g
P108563-500g
2
$79.90
12×500g
P108563-12×500g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$799.90
Enter a quantity for the sizes you want to add.
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Why this grade

AR, ≥98% AR for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Room temperature,Argon charged Ships FedEx DG Service Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 31 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Used in the spectrophotmetric determination of Al, Cr, Mo, Ti, and Zr.

Specifications

Synonyms
Hydrazinobenzene | Monophenylhydrazine
Specifications & Purity
AR, ≥98%
Storage
Protected from light, Room temperature, Argon charged
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
AR
Purity
≥98%
Names and Identifiers
Pubchem Sid504751376
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504751376
Canonical SmilesC1=CC=C(C=C1)NN
IUPAC Namephenylhydrazine
InChIKeyHKOOXMFOFWEVGF-UHFFFAOYSA-N
INCHI1S/C6H8N2/c7-8-6-4-2-1-3-5-6/h1-5,8H,7H2
Isomeric SMILES C1=CC=C(C=C1)NN
WGK Germany 3
RTECS MV8925000
UN Number 2572
Packing Group II
Molecular Weight 108.14
Beilstein 606080
Reaxy-Rn 606080
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=606080&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassPhenylhydrazines
Intermediate Tree Nodes Not available
Direct ParentPhenylhydrazines
Alternative Parents Organopnictogen compounds  Hydrocarbon derivatives  Hydrazines and derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Phenylhydrazine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Hydrazine derivative - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent attached to a phenyl group.
External Descriptors a small molecule
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CYP3A4 Tclin Cytochrome P450 3A4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDO1 Tchem Indoleamine 2,3-dioxygenase 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ido1 Indoleamine 2,3-dioxygenase 1 (313 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

43 results found

Lot NumberCertificate TypeDateItem
D2412457Certificate of AnalysisJan 21, 2026 P108563
D2412461Certificate of AnalysisJan 21, 2026 P108563
G2221445Certificate of AnalysisJan 19, 2026 P108563
J2331403Certificate of AnalysisAug 11, 2025 P108563
F2512301Certificate of AnalysisJun 21, 2025 P108563
A2607040Certificate of AnalysisApr 12, 2025 P108563
G2509243Certificate of AnalysisApr 12, 2025 P108563
G2509242Certificate of AnalysisApr 12, 2025 P108563
G2509241Certificate of AnalysisApr 12, 2025 P108563
E2305565Certificate of AnalysisFeb 07, 2025 P108563
E2305572Certificate of AnalysisFeb 07, 2025 P108563
C2513240Certificate of AnalysisDec 31, 2024 P108563
C2513241Certificate of AnalysisDec 31, 2024 P108563
C2513242Certificate of AnalysisDec 31, 2024 P108563
I2402337Certificate of AnalysisAug 26, 2024 P108563
I2402335Certificate of AnalysisAug 26, 2024 P108563
I2402334Certificate of AnalysisAug 26, 2024 P108563
L2403284Certificate of AnalysisAug 26, 2024 P108563
B2512038Certificate of AnalysisAug 26, 2024 P108563
G2221444Certificate of AnalysisAug 21, 2024 P108563
H2414016Certificate of AnalysisAug 07, 2024 P108563
H2414017Certificate of AnalysisAug 07, 2024 P108563
E2415388Certificate of AnalysisApr 29, 2024 P108563
E2415387Certificate of AnalysisApr 29, 2024 P108563
G2205379Certificate of AnalysisApr 07, 2024 P108563
G2221449Certificate of AnalysisApr 07, 2024 P108563
L2403454Certificate of AnalysisMar 16, 2024 P108563
D2412463Certificate of AnalysisMar 04, 2024 P108563
D2412455Certificate of AnalysisMar 04, 2024 P108563
J2331404Certificate of AnalysisOct 25, 2023 P108563
E2305566Certificate of AnalysisApr 20, 2023 P108563
E2305562Certificate of AnalysisApr 20, 2023 P108563
J2325014Certificate of AnalysisApr 17, 2023 P108563
G2117316Certificate of AnalysisApr 17, 2023 P108563
G2117313Certificate of AnalysisApr 17, 2023 P108563
C2301638Certificate of AnalysisFeb 23, 2023 P108563
G2221480Certificate of AnalysisJun 15, 2022 P108563
G2205381Certificate of AnalysisJun 15, 2022 P108563
G2205380Certificate of AnalysisJun 15, 2022 P108563
J2325016Certificate of AnalysisJun 15, 2022 P108563
F2225415Certificate of AnalysisJun 15, 2022 P108563
B2216182Certificate of AnalysisFeb 19, 2022 P108563
C2310618Certificate of AnalysisJul 05, 2021 P108563

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Chemical and Physical Properties
SolubilityInsoluble in cold water, soluble in most organic solvents such as hot water, ethanol, ether, benzene, etc.
SensitivityAir and Light sensitive.
Freezing Point(°C)19 °C
Refractive Index1.60813
Flash Point(°F)192.2 °F
Flash Point(°C)89℃
Boil Point(°C)243.5°C
Melt Point(°C)19.50°C
Molecular Weight108.140 g/mol
XLogP31.200
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass108.069 Da
Monoisotopic Mass108.069 Da
Topological Polar Surface Area38.100 Ų
Heavy Atom Count8
Formal Charge0
Complexity57.500
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
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25. Lei Yang, Zifei Wei, Zihan Guo, Mengfang Chen, Jingchun Yan, Linbo Qian, Lu Han, Jing Li, Mingyue Gu.  (2022)  Significant roles of surface functional groups and Fe/Co redox reactions on peroxymonosulfate activation by hydrochar-supported cobalt ferrite for simultaneous degradation of monochlorobenzene and p-chloroaniline.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:37055992] [10.1016/j.jhazmat.2022.130588]
26. Jiaqi Shi, Yan Li, Qi Wei, Xin Zhu, Shaohua Cao, Wenyi Xie, Yang Guo, Jing Wei, Zekai Li, Tao Long.  (2025)  Interaction between 6PPD/6PPD-Q and natural Fe-Mn nodules: Performance and mechanism of adsorption and oxidative transformation.  ENVIRONMENT INTERNATIONAL,      [PMID:40220692] [10.1016/j.envint.2025.109438]
27. Jinli Liu, Mo Zhang, Ling Tang, Simin Zhang, Jiayong Lu, Xu Yang, Yangming Lin.  (2025)  Surface hybrid engineering of nanodiamonds for boosting electrocatalytic hydrogen peroxide production with high efficiency and stability.  Journal of Energy Chemistry,      [PMID:] [10.1016/j.jechem.2025.04.026]
28. Dan Wang, Yanan Liu, Kun Wan, Danning Feng, Yan Pei, Minghua Qiao, Xiaoxin Zhang, Baoning Zong.  (2025)  One-Step Carbonization of Monosaccharide and Dicyandiamide to Oxygen and Nitrogen Co-Doped Carbon Nanosheets for Electrocatalytic O2 Reduction to H2O2.  Catalysts,  15  (5): (459).  [PMID:] [10.3390/catal15050459]
29. Yiming Wang, Xiang Meng, Xuting Song, Lulu Wang, Xianghe Meng, Xiaoya Du, Ziyoviddin Yusupov, Komiljon Tojibaev, Yunpeng Wang, Min He, Mengmeng Sun.  (2025)  Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review.  Frontiers in Pharmacology,      [PMID:41394135] [10.3389/fphar.2025.1713417]
30. Tianyuan Xu, Nanxi Zhu, Ruina Yuan, Yaowen Xing, Xiahui Gui.  (2026)  Persulfate activation by low-rank coals for sulfamethazine degradation: Structural differences modulating activation pathways.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2025.109417]
31. Dingfu Wang, Dan Li, Xiaolin Liu, Shixin Wang, Yile Fan, Ling Lu, Chuanbin Shen, Chunxia Li.  (2026)  Smart hypoxia-responsive sulfated polysaccharides liposomes for controlled and targeted urokinase delivery in thrombotic therapy.  JOURNAL OF CONTROLLED RELEASE,      [PMID:41621757] [10.1016/j.jconrel.2026.114669]
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