Transferrin (HOLO) from Human Plasma, CAS No.11096-37-0

CAS: 11096-37-0 Cat. No.: np001013

GRADE & PURITY BioReagent, Native, Low Endotoxin, Tissue Culture Grade, PBS Only, ≥95%(SDS-PAGE), Iron Content: >1μg/mg; Pre-lyophilization Protein Concentration: See COA

Accession #

P02787

Endotoxin Concentration

<0.1 EU/mg

Overview

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100 ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and prevention of iron loss via the kidneys. Stored in bone marrow as Tf-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypoproteinemias and nephrotic syndrome; increases are found in pregnancy, iron-deficiency anemias, and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important transport factor used in defined culture media.

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

Purity: ≥95% by SDS PAGE

Iron Content: >1μg iron/mg protein

Endotoxin level: <0.1 EU/mg by LAL testing

Specifications

Product Name

Transferrin (HOLO) from Human Plasma, CAS No.11096-37-0

Synonyms

Serotransferrin | TF | TFQTL1 | PRO1557 | PRO2086 | HEL-S-71p | Serotransferrin | TF | TFQTL1 | PRO1557 | PRO2086 | HEL-S-71p

Grade

BioReagent, Low Endotoxin, Native, PBS Only, Tissue Culture Grade

Specifications & Purity

BioReagent, Native, Low Endotoxin, Tissue Culture Grade, PBS Only, ≥95%(SDS-PAGE), Iron Content: >1μg/mg; Pre-lyophilization Protein Concentration: See COA

Biochemical and Physiological Mechanisms

Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage a

Endotoxin Concentration

<0.1 EU/mg

Accession #

P02787

Predicted molecular weight

80 kDa

CAS

11096-37-0

Molecule Type

Protein

Product Properties

• ALogP: -2.5

Storage and Shipping

Shape

Lyophilized from 20 mM Na Phosphate, pH 7.4, and 150 mM NaCl

Concentration

Iron Content: >1μg/mg; Pre-lyophilization Protein Concentration: See COA

Reconstitution

After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at -20℃ long term (>1 year). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.

References

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