Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
| Canonical Smiles | CNCC(C1=CC(=C(C=C1)O)O)O |
|---|---|
| IUPAC Name | 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol |
| InChIKey | UCTWMZQNUQWSLP-UHFFFAOYSA-N |
| INCHI | 1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 |
| Isomeric SMILES | CNCC(C1=CC(=C(C=C1)O)O)O |
| UN Number | 2811 |
| Packing Group | I |
| Molecular Weight | 183.2 |
| Reaxy-Rn | 2212160 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2212160&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Phenols |
| Subclass | Benzenediols |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Catechols |
| Alternative Parents | Aralkylamines 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Benzene and substituted derivatives Secondary alcohols 1,2-aminoalcohols Dialkylamines Organopnictogen compounds Hydrocarbon derivatives Aromatic alcohols |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Monocyclic benzene moiety - 1,2-aminoalcohol - Secondary alcohol - Secondary amine - Secondary aliphatic amine - Aromatic alcohol - Alcohol - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Organopnictogen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as catechols. These are compounds containing a 1,2-benzenediol moiety. |
| External Descriptors | catecholamine |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 11, 2026 | D274858 |
| Solubility | Soluble in DMSO |
|---|---|
| Sensitivity | light sensitive |
| Melt Point(°C) | 197° |
| Molecular Weight | 183.200 g/mol |
| XLogP3 | -1.400 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 183.09 Da |
| Monoisotopic Mass | 183.09 Da |
| Topological Polar Surface Area | 72.700 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 154.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xin Song, Jiaqi Li, Mingxuan Yu, Yuhui Fan, Haibin Niu, Li Liu, Chao Zhou, Guangfeng Wu. (2023) Interfacial and interlayer enhancement of highly hydrophilic dual-affinity waterborne polyurethane sizing agent acting on carbon fiber/epoxy resin composites. PROGRESS IN ORGANIC COATINGS, [PMID:] [10.1016/j.porgcoat.2023.107687] |
| 2. Guiyan Yang, Youyi Sun, Limin qin, Mengru Li, Kangtai Ou, Jiang Fang, Qiang Fu. (2021) Direct-ink-writing (DIW) 3D printing functional composite materials based on supra-molecular interaction. COMPOSITES SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.compscitech.2021.109013] |
| 3. Kai Hu, Tiantian Pang, Yanmei Shi, Pengzhao Han, Yuanqing Zhao, Wenjie Zhao, Huahui Zeng, Shusheng Zhang, Zhenqiang Zhang. (2021) Magnetic borate-modified Mxene: A highly affinity material for the extraction of catecholamines. ANALYTICA CHIMICA ACTA, [PMID:34399896] [10.1016/j.aca.2021.338769] |
| 4. Weilu Liu, Fan Cui, Haifeng Li, Shuang Wang, Beibei Zhuo, Shuang Wang. (2020) Three-dimensional hybrid networks of molecularly imprinted poly(9-carbazoleacetic acid) and MWCNTs for simultaneous voltammetric determination of dopamine and epinephrine in plasma sample. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2020.128669] |
| 5. Dan Wang, Zhigang Xu, Yuanchen Liu, Yujian Liu, Gongke Li, Xiaoxi Si, Tao Lin, Hongcheng Liu, Zhimin Liu. (2020) Molecularly imprinted polymer-based fiber array extraction of eight estrogens from environmental water samples prior to high-performance liquid chromatography analysis. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2020.105376] |
| 6. Li Chi, Zhang Yuanyuan, Li Chunya, Wan Qijin, Ke Qiang, Yang Nianjun. (2020) Tailoring the CeO2 morphology and its electrochemical reactivity for highly sensitive and selective determination of dopamine and epinephrine. MICROCHIMICA ACTA, 187 (2): (1-9). [PMID:31965337] [10.1007/s00604-019-4100-7] |
| 7. Qiwen Wang, Haipei Si, Lihui Zhang, Ling Li, Xiaohong Wang, Shengtian Wang. (2020) A fast and facile electrochemical method for the simultaneous detection of epinephrine, uric acid and folic acid based on ZrO2/ZnO nanocomposites as sensing material. ANALYTICA CHIMICA ACTA, [PMID:32106959] [10.1016/j.aca.2020.01.012] |
| 8. Chen Li, Xuejuan Chen, Zhe Zhang, Jilin Tang, Bailin Zhang. (2018) Gold Nanoparticle-DNA conjugates enhanced determination of dopamine by aptamer-based microcantilever array sensor. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2018.08.024] |
| 9. Yi Xin, Wu Yuxuan, Tan Guoxin, Yu Peng, Zhou Lei, Zhou Zhengnan, Chen Junqi, Wang Zhengao, Pang Jinshan, Ning Chengyun. (2017) Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor. Scientific Reports, 7 (1): (1-9). [PMID:28801614] [10.1038/s41598-017-07909-y] |
| 10. Hongmei Chen, Han Zhang, Ruo Yuan, Shihong Chen. (2017) Novel Double-Potential Electrochemiluminescence Ratiometric Strategy in Enzyme-Based Inhibition Biosensing for Sensitive Detection of Organophosphorus Pesticides. ANALYTICAL CHEMISTRY, [PMID:28192982] [10.1021/acs.analchem.6b03883] |
| 11. Lin Jiang, Shuqing Gu, Yaping Ding, Daixin Ye, Zhen Zhang, Fenfen Zhang. (2013) Amperometric sensor based on tricobalt tetroxide nanoparticles–graphene nanocomposite film modified glassy carbon electrode for determination of tyrosine. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:23475062] [10.1016/j.colsurfb.2013.01.077] |
| 12. Xiao Liu, Liqiang Luo, Yaping Ding, Qingsheng Wu, Youli Wei, Daixin Ye. (2012) A highly sensitive method for determination of guanine, adenine and epinephrine using poly-melamine film modified glassy carbon electrode. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, [PMID:] [10.1016/j.jelechem.2012.04.026] |
| 13. Zhongming Wang, Zhiyuan He, Zhongsheng Wang, Jixu Yang, Kecheng Long, Zhibin Wu, Gang Zhou, Lin Mei, Libao Chen. (2024) A nitrile solvent structure induced stable solid electrolyte interphase for wide-temperature lithium-ion batteries. Chemical Science, [PMID:39211494] [10.1039/D4SC03890H] |
| 14. Aiting Chen, Nana Tang, Yanping Wei, Shuting Shi, Chuanqin Zhou, Quanguo He, Wu Wang. (2024) A novel approach to simultaneous and sensitive detection of epinephrine and folic acid with nickel-metal organic framework and reduced graphene oxide based electrochemical sensor. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112526] |
| 15. Jie Xu, Delei Liu. (2024) A Study on the Radiation Cooling Characteristics of Cerambycini Latreille. Biomimetics, 9 (1): (34). [PMID:38248608] [10.3390/biomimetics9010034] |
| 16. Zhikang Rao, Boyu Guo, Jixiang Zu, Weiqiang Zheng, Ying Xu, Yuting Yang. (2024) Construction of an ECL-DPV dual model biosensor for dopamine detection based on PSO-ANN algorithm. IEEE SENSORS JOURNAL, [PMID:] [10.1109/JSEN.2024.3358413] |
| 17. Wang Yichun, Xia Yu. (2024) Deep profiling of plasmalogens by coupling the Paternò–Büchi derivatization with tandem mass spectrometry. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 416 (19): (4397-4407). [PMID:38861160] [10.1007/s00216-024-05376-9] |
| 18. Weiyou Zhang, Yongpeng Sun, Xianghua Meng, Rutong Dou. (2025) Preparation and Mechanism of EP-HMTA-SiO2 Nanocomposite Polymer Gel for Enhancing Oil Recovery. Processes, 13 (3): (596). [PMID:] [10.3390/pr13030596] |
| 19. Xuemei Shang, Mei Yang, Tiantian Su, Junli Guo, Chenxi Zhao, Pei Song, Yan-Yan Song, Yucen Li. (2025) Modulation of Electron Transport via Target Recognition in Asymmetric Nanochannel Arrays for Enantiomer Detection. ANALYTICAL CHEMISTRY, [PMID:40600873] [10.1021/acs.analchem.5c02831] |
| 20. Haining Du, Jiaxin Li, Xiangjuan Wei, Daqian Yang, Boya Zhang, Xingpei Fan, Meimei Zhao, Ruijiao Zhu, Ziyi Zhang, Yuxia Zhang, Xiaoyan Li, Ning Gu. (2024) Methylparaben induces hepatic glycolipid metabolism disorder by activating the IRE1α-XBP1 signaling pathway in male mice. ENVIRONMENT INTERNATIONAL, [PMID:38262168] [10.1016/j.envint.2024.108445] |
| 21. Shuyan Liu, Xiuyu Du, Kuan Ji, Lili Lv, Yu Zhou. (2025) Mechanism of azeotrope elimination in the ethyl propionate–ethanol system using ionic liquid HMIMOAc as an entrainer: Experimental and theoretical insights. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, [PMID:40387582] [10.1039/D5CP01219H] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →