RET-IN-3 - 10mM in DMSO , CAS No.2414374-53-9

CAS: 2414374-53-9 Cat. No.: R655025 Molecular Weight: 339.4 PubChem CID: 146018674
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
R655025-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$770.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC 50 of 19 nM

In Vitro

RET-IN-3 exhibits 16 and 410 fold selectivity compared to wt-RET and KDR, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 19 nM (RETV804M)

Specifications

Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC 50 of 19 nM.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES CN(C)CCCNC1=NC2=C(C=NN2C=C1)C3=CC4=C(C=C3)OCO4
PubChem CID 146018674
Molecular Weight 339.4

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
RET Tclin Proto-oncogene tyrosine-protein kinase receptor Ret (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews

Customer Reviews

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