≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Conservar a -20°C Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Aplicación del producto：
El tratamiento con TW-37 inhibió significativamente el crecimiento de tumores pancreáticos in vivo. El análisis por Western blot mostró que el nivel de expresión de Notch-1 era significativamente menor en los tumores de los ratones tratados con TW-37 que en los de los ratones de control tratados con vehículo. Además, la expresión de Jagged-1 y del gen diana de Notch-1, Hes-1, también disminuyó en los tumores tratados con TW-37.
El TW-37 es un inhibidor de Bcl-2 (los valores Ki son 0,29 μM y 1,11 μM para Bcl-2 y Bcl-XL respectivamente). La TW-37 inhibe el potencial angiogénico de las células endoteliales in vitro. La TW-37 induce la detención de la fase S y la apoptosis en líneas
Condiciones de almacenamiento de almacenamiento
Conservar a -20°C
Enviado en
Hielera + almohadillas de hielo
Nota
Consulte la SDS para obtener más información ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.
This compound belongs to the class of organic compounds known as benzanilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with a benzene ring. They have the general structure RNC(=O)R', where R,R'= benzene.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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Preguntas frecuentes
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 877877-35-5, the molecular formula is C33H35NO6S, and the molecular weight is 573.71 g/mol. InChIKey PQAPVTKIEGUPRN-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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