C2223718Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Cetuximab (anti-EGFR) - Primary antibody
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Why this grade
Moligand™, ≥95%, Protein concentration：5mg/ml Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Cetuximab (C225) is a monoclonal antibody that inhibits epidermal growth factor receptor (EGFR), with a Kd of 0.201 nM for EGFR by SPR. Cetuximab has potent antitumor activity.
Amino acid sequence
QVQLKQSGPG LVQPSQSLSI TCTVSGFSLT NYGVHWVRQS PGKGLEWLGV 50IWSGGNTDYN TPFTSRLSIN KDNSKSQVFF KMNSLQSNDT AIYYCARALT 100YYDYEFAYWG QGTLVTVSAA STKGPSVFPL APSSKSTSGG TAALGCLVKD 150YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTQTY 200ICNVNHKPSN TKVDKRVEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK 250DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS 300TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV 350YTLPPSREEM TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL 400DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK 449
DILLTQSPVI LSVSPGERVS FSCRASQSIG TNIHWYQQRT NGSPRLLIKY 50ASESISGIPS RFSGSGSGTD FTLSINSVES EDIADYYCQQ NNNWPTTFGA 100GTKLELKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV 150DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG 200LSSPVTKSFN RGEC 214
Specifications
Product Name
Cetuximab (anti-EGFR) - Primary antibody
Specifications & Purity
Moligand™, ≥95%, Protein concentration：5mg/ml
Host species
Human
Conjugation
Unconjugated
Grade
Moligand™
Concentration
Protein concentration：5mg/ml
CAS
205923-56-4
Storage and Shipping
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Associated Targets(Human)
EGFR Tclin Epidermal growth factor receptor (0 Activities)
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
References
| 1. Liyin Wang, Milad Ashrafizadeh, Gautam Sethi, Xinjia Zhou. (2025) pH-responsive biomimetic zeolitic imidazolate framework-based nanoparticles for co-delivery of cetuximab and siRNA in synergistic therapy of laryngeal squamous cell carcinoma. Journal of Pharmaceutical Analysis, [PMID:40735032] [10.1016/j.jpha.2025.101203] |
| 2. Li Jinbo, Yu Jiang, Song Jia, Zhang Yingxi, Li Ning, Wang Zhaomeng, Qin Meng, Zhao Mingming, Zhang Baoyue, Huang Ruiping, Zhou Shuang, Liu Yubo, He Zhonggui, Liu Hongzhuo, Dan Liu, Wang Yongjun. (2025) Galloylated liposomes enable targeted drug delivery by overcoming protein corona shielding. Nature Communications, 16 (1): (1-15). [PMID:40854890] [10.1038/s41467-025-63198-4] |
Solution Calculators
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