Animal models of thymus deprivation and senescence

Summary

The thymus is an important lymphatic organ of the body. Its function is closely related to immunity. It secretes thymic hormones and hormone-like substances, and is an organ with endocrine functions. It is located in the anterior mediastinum of the thoracic cavity. In the late embryonic period and at birth, the human thymus weighs about 10 to 15 grams, which is the relatively heaviest period in a person's life. With age, the thymus continues to develop and reaches about 30-40 grams at puberty. Thereafter, the thymus gradually degenerates, with a decrease in lymphocytes and an increase in adipose tissue, to only 15 grams in old age.

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