Lalistat 1 - ≥98%(HPLC) , CAS No.501104-16-1

CAS: 501104-16-1 Cat. No.: L287177 Molecular Weight: 298.36
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate | 4-morpholinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
L287177-5mg
3

$61.90

$92.90
Save $31.00 (33.37%)
10mg
L287177-10mg
3

$91.90

$137.90
Save $46.00 (33.36%)
25mg
L287177-25mg
3

$201.90

$302.90
Save $101.00 (33.34%)
50mg
L287177-50mg
3

$361.90

$542.90
Save $181.00 (33.34%)
Enter a quantity for the sizes you want to add.
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
4-(Piperidin-1-yl)-1, 2, 5-thiadiazol-3-yl morpholine-4-carboxylate | 4-morpholinecarboxylic acid, 4-(1-piperidinyl)-1, 2, 5-thiadiazol-3-yl ester
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent and selective lysosomal acid lipase (LAL) inhibitor (IC50= 68 nM). Exhibits no significant activity against pancreatic lipase or lipoprotein lipase at 10 μM concentration. Blocks LAL-mediated lipid hydrolysis of acetylated LDL and reduces efflux of
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%(HPLC)
Names and Identifiers
Canonical SmilesC1CCN(CC1)C2=NSN=C2OC(=O)N3CCOCC3
IUPAC Name(4-piperidin-1-yl-1,2,5-thiadiazol-3-yl) morpholine-4-carboxylate
InChIKeyXAWUWPUYJUOUOF-UHFFFAOYSA-N
INCHI1S/C12H18N4O3S/c17-12(16-6-8-18-9-7-16)19-11-10(13-20-14-11)15-4-2-1-3-5-15/h1-9H2
Isomeric SMILES C1CCN(CC1)C2=NSN=C2OC(=O)N3CCOCC3
Molecular Weight 298.36
Reaxy-Rn 20694905
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20694905&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassOxazinanes
SubclassMorpholines
Intermediate Tree Nodes Morpholine carboxylic acids and derivatives
Direct ParentMorpholine carboxylic acids
Alternative Parents Dialkylarylamines  Piperidines  Imidolactams  Thiadiazoles  Heteroaromatic compounds  Carbamate esters  Organic carbonic acids and derivatives  Oxacyclic compounds  Dialkyl ethers  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Morpholine-4-carboxylic acid - Dialkylarylamine - Piperidine - Imidolactam - Azole - Thiadiazole - Carbamic acid ester - Heteroaromatic compound - Carbonic acid derivative - Ether - Azacycle - Oxacycle - Dialkyl ether - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as morpholine carboxylic acids. These are heterocyclic compounds containing a morpholine ring substituted by one or more carboxylic acid groups.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
LIPA Tchem Lysosomal acid lipase/cholesteryl ester hydrolase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
LIPA Tchem Lysosomal acid lipase/cholesteryl ester hydrolase (63 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
J2209414Certificate of AnalysisJul 10, 2025 L287177
J2209415Certificate of AnalysisJul 10, 2025 L287177
J2209411Certificate of AnalysisJul 10, 2025 L287177
J2209412Certificate of AnalysisJul 10, 2025 L287177
J2209413Certificate of AnalysisJul 10, 2025 L287177
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 29.84, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 29.84, Max Conc. mM: 100
SensitivityMoisture sensitive
Molecular Weight298.360 g/mol
XLogP31.400
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass298.11 Da
Monoisotopic Mass298.11 Da
Topological Polar Surface Area96.000 Ų
Heavy Atom Count20
Formal Charge0
Complexity335.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

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