GRADE & PURITYRecombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.0.3 mg/mL
ExactAb™, Validated, Recombinant, 0.3 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Rabbit anti Human FE65 Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200 Protein Function： Transcription coregulator that can have both coactivator and corepressor functions. Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain. Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1. Required for histone H4 acetylation at double-strand breaks (DSBs). Its ability to specifically bind modified histones and chromatin modifying enzymes such as KAT5/TIP60, probably explains its trancription activation activity. Function in association with TSHZ3, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s).
Specifications
Product Name
Recombinant FE65 Antibody - Primary antibody, specific to FE65, Rabbit IgG
Synonyms
APBB1_HUMAN antibody | FE 65 antibody | Fe65 protein antibody | Protein Fe65 antibody | RIR antibody | stat like protein antibody | RIR | FE65 | MGC:9072 | Adaptor protein FE65a2 antibody | Amyloid beta (A4) precursor protein binding family B member 1 ant
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.3 mg/mL
Host species
Rabbit
Specificity
FE65
Immunogen
A synthetic peptide derived from human FE65 (AA 697-710)
Positive Control
WB: A549, SK-N-SH, U-2 OS and HEK293 cell lysates. IHC: Human lung cancer tissue. ICC/IF: 293T cells.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Antigen affinity purified
Concentration
0.3 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant FE65 Antibody (Ab103161) - Western Blot All lanes: Recombinant FE65 Antibody (Ab103161) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 77 kDa Observed band size: 70, 91 kDa Exposure time: 17.1 s
Recombinant FE65 Antibody (Ab103161) - IHC Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Recombinant FE65 Antibody (Ab103161). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Recombinant FE65 Antibody (Ab103161) - IF/ICC Immunocytochemistry analysis of FE65 (green) in 293T using Recombinant FE65 Antibody (Ab103161) and DAPI (blue).
Application
Application
Dilution info
IF/ICC
1/50-1/200
IHC
1/50 - 1/100
WB
1/500-1/1000
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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