≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Dithioerythritol is an epimer of dithiothreitol and an erythro isomer of 2,3-dihydroxy-1,4- dithiolbutane. The compound is a protective agent for thiol groups and strong reducing agent that is capable of reducing disulfide bonds.
A useful reagent for maintaining sulfhydryl groups in the reduced state
| Canonical Smiles | C(C(C(CS)O)O)S |
|---|---|
| IUPAC Name | (2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol |
| InChIKey | VHJLVAABSRFDPM-ZXZARUISSA-N |
| INCHI | 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+ |
| Isomeric SMILES | C([C@H]([C@H](CS)O)O)S |
| WGK Germany | 3 |
| RTECS | KF2410000 |
| Alternate CAS | 7634-42-6 |
| Molecular Weight | 154.25 |
| Beilstein | 1719756 |
| Reaxy-Rn | 9483598 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9483598&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Alcohols and polyols |
| Intermediate Tree Nodes | Polyols |
| Direct Parent | 1,2-diols |
| Alternative Parents | Secondary alcohols Alkylthiols Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Secondary alcohol - 1,2-diol - Alkylthiol - Hydrocarbon derivative - Organosulfur compound - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as 1,2-diols. These are polyols containing an alcohol group at two adjacent positions. |
| External Descriptors | 1,4-dimercaptobutane-2,3-diol |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2220346 | Certificate of Analysis | Apr 02, 2026 | D105710 |
| F2220368 | Certificate of Analysis | Apr 02, 2026 | D105710 |
| C2202194 | Certificate of Analysis | Dec 12, 2025 | D105710 |
| A1830082 | Certificate of Analysis | Aug 19, 2025 | D105710 |
| H2518308 | Certificate of Analysis | Jul 31, 2025 | D105710 |
| H2518309 | Certificate of Analysis | Jul 31, 2025 | D105710 |
| H2518310 | Certificate of Analysis | Jul 31, 2025 | D105710 |
| J2524055 | Certificate of Analysis | Jul 31, 2025 | D105710 |
| G2529244 | Certificate of Analysis | Jul 12, 2025 | D105710 |
| K1901176 | Certificate of Analysis | Aug 08, 2023 | D105710 |
| Solubility | Soluble in water (50 mg/ml), and methanol. |
|---|---|
| Sensitivity | Moisture & Heat sensitive；Air sensitive |
| Melt Point(°C) | 82-86°C |
| Molecular Weight | 154.300 g/mol |
| XLogP3 | -0.400 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 154.012 Da |
| Monoisotopic Mass | 154.012 Da |
| Topological Polar Surface Area | 42.500 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 52.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jie Wang, Shanshan Huang, Kangle Yan, Jihua Shi, Shuo Shi, Yu Jin, Liang Yuan. (2023) Sustainable macromolecular antioxidants from eugenol with synergistically enhanced storage stability for active PVA packaging. REACTIVE & FUNCTIONAL POLYMERS, [PMID:] [10.1016/j.reactfunctpolym.2023.105671] |
| 2. Hongzhi Yang, Fengqin Yin, Yeling Mo, Kaixuan Huo, Kun Zhang, Hui Cao, Min Yuan, Tai Ye, Chunyan Luo, Fei Xu. (2023) An ion imprinted electrochemical sensor based on flower-like gold nanoparticles for the detection of trace arsenic(III) ions in water and food samples. ELECTROANALYSIS, 35 (8): (e202200513). [PMID:] [10.1002/elan.202200513] |
| 3. Rui Zhao, Xiufeng Cao, Xinxin Li, Tao Li, Hong Zhang, Xiaowei Cui, Zhaojie Cui. (2022) Ecological toxicity of Cd, Pb, Zn, Hg and regulation mechanism in Solanum nigrum L.. CHEMOSPHERE, [PMID:36509194] [10.1016/j.chemosphere.2022.137447] |
| 4. Zhihong Yin, Shuangxi Li, Dan Hu, Zhuo Li, Ruoyu Chu, Chenchen Liu, Xinzhu Li, Jiangjun Hu, Liandong Zhu. (2021) Performance evaluation of different chitosan-clay composite materials for efficient harvesting of Chlorella vulgaris and impacts on downstream bioproduct processing and water reusability. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2021.132892] |
| 5. Pengchong Wang, Yan Yan, Ying Sun, Rui Zhang, Chuanchuan Huo, Lu Li, Ke Wang, Yalin Dong, Jianfeng Xing. (2019) Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery. Journal of Materials Chemistry B, 7 (44): (6994-7005). [PMID:31625545] [10.1039/C9TB01183H] |
| 6. Shaopeng Xie, Dezhi Yang, Qiulan Li, Jitao Li, Dubo Zhong, Ye Yang, Yaling Yang, Hua Wang. (2025) Effects of functional groups on carbon dots-based AuNPs for the specific detection of mercury ions. CARBON, [PMID:] [10.1016/j.carbon.2025.120481] |
