Indo-1 AM (Calcium Ion Fluorescent Probe) - BioReagent, Biological Stain, for fluorescence analysis, for microscopy, ≥96% , CAS No.112926-02-0

CAS: 112926-02-0 Cat. No.: I1455253 Molecular Weight: 1009.91 PubChem CID: 123918

GRADE & PURITY BioReagent, Biological Stain, for Fluorescence analysis, for Microscopy, ≥96%

Synonyms

Indo-1 AM | Indo-1 Acetoxymethyl ester | Bis(acetoxymethyl) 2,2'-((4-(6-((acetoxymethoxy)carbonyl)-1H-indol-2-yl)-2-(2-(2-(bis(2-(acetoxymethoxy)-2-oxoethyl)amino)-5-methylphenoxy)ethoxy)phenyl)azanediyl)diacetate

Storage

Protected from light,Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Application

Cell Staining‌, Fluorescence Analysis

Overview

Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues.MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions.

Specifications

Synonyms

Indo-1 AM | Indo-1 Acetoxymethyl ester | Bis(acetoxymethyl) 2, 2'-((4-(6-((acetoxymethoxy)carbonyl)-1H-indol-2-yl)-2-(2-(2-(bis(2-(acetoxymethoxy)-2-oxoethyl)amino)-5-methylphenoxy)ethoxy)phenyl)azanediyl)diacetate

Specifications & Purity

BioReagent, Biological Stain, for fluorescence analysis, for microscopy, ≥96%

Stability And Storage

Store at -20℃ long term (12 months). Store in the dark. Avoid freeze/thaw cycle.

Storage

Protected from light, Store at -20°C, Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Biological Stain, BioReagent, for Fluorescence analysis, for Microscopy

Purity

≥96%

Names and Identifiers

• Canonical Smiles: CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=CC4=C(N3)C=C(C=C4)C(=O)OCOC(=O)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
• IUPAC Name: acetyloxymethyl 2-[4-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-3-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylate
• InChIKey: CAWBRCOBJNWRLK-UHFFFAOYSA-N
• INCHI: 1S/C47H51N3O22/c1-28-7-11-39(49(19-43(56)68-23-63-29(2)51)20-44(57)69-24-64-30(3)52)41(15-28)61-13-14-62-42-18-35(37-16-34-8-9-36(17-38(34)48-37)47(60)72-27-67-33(6)55)10-12-40(42)50(21-45(58)70-25-65-31(4)53)22-46(59)71-26-66-32(5)54/h7-12,15-18,48H,13-14,19-27H2,1-6H3
• Isomeric SMILES: CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=CC4=C(N3)C=C(C=C4)C(=O)OCOC(=O)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
• PubChem CID: 123918
• Molecular Weight: 1009.91

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Indoles and derivatives
      • Subclass Indoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Indoles and derivatives
• Subclass: Indoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 2-phenylindoles
• Alternative Parents: Alpha amino acid esters Indolecarboxylic acids Phenylpyrroles Aminophenyl ethers Dialkylarylamines Aniline and substituted anilines Aminotoluenes Phenoxy compounds Alkyl aryl ethers Acylals Heteroaromatic compounds Azacyclic compounds Acetals Organopnictogen compounds Hydrocarbon derivatives Carbonyl compounds Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 2-phenylindole - Alpha-amino acid ester - Indolecarboxylic acid - Indolecarboxylic acid derivative - 2-phenylpyrrole - Alpha-amino acid or derivatives - Aminophenyl ether - Phenoxy compound - Phenol ether - Aminotoluene - Aniline or substituted anilines - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Alkyl aryl ether - Acylal - Toluene - Monocyclic benzene moiety - Substituted pyrrole - Benzenoid - Pyrrole - Heteroaromatic compound - Tertiary amine - Amino acid or derivatives - Carboxylic acid ester - Azacycle - Acetal - Carboxylic acid derivative - Ether - Organooxygen compound - Organic oxide - Carbonyl group - Hydrocarbon derivative - Organonitrogen compound - Amine - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 2-phenylindoles. These are indoles substituted at the 2-position with a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in DMSO
• Sensitivity: Light-sensitive