Dual specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2)

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  1. Curcumin
    CAS: 458-37-7 EC Number: 207-280-5 Formula: C21H20O6 Molecular Weight: 368.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥65%
    In Stock Item #: C140600
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    IUPAC Name
    (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
    SMILES
    COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
    InChIKey
    VFLDPWHFBUODDF-FCXRPNKRSA-N
    InChI
    1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
    Synonyms
    BIDD:ER0479 | Golden seal | NSC 687842 | Ukon (dye) | Victory 19 Virus Out | CURCUMIN (MART.) | Yellow Ginger | Zlut ...
  2. 7BIO
    CAS: 916440-85-2 PubChem CID: 135423792 Formula: C16H10BrN3O2 Molecular Weight: 356.17
    In Stock Item #: B338496
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    IUPAC Name
    7-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol
    SMILES
    C1=CC=C2C(=C1)C(=C(N2)C3=C(NC4=C3C=CC=C4Br)O)N=O
    InChIKey
    HYMACPDEJIEMST-UHFFFAOYSA-N
    InChI
    1S/C16H10BrN3O2/c17-10-6-3-5-9-12(16(21)19-13(9)10)15-14(20-22)8-4-1-2-7-11(8)18-15/h1-7,18-19,21H
    Synonyms
    7-Bromoindirubin-3'-oxime | 7-bromo-3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
  3. AZ 191, Inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1B
    CAS: 1594092-37-1 Formula: C24H27N7O Molecular Weight: 429.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A288802
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    IUPAC Name
    N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
    SMILES
    CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=CC(=N3)C4=CN(C5=C4C=CN=C5)C)OC
    InChIKey
    ZYVXTMKTGDARKR-UHFFFAOYSA-N
    InChI
    1S/C24H27N7O/c1-29-10-12-31(13-11-29)17-4-5-21(23(14-17)32-3)28-24-26-9-7-20(27-24)19-16-30(2)22-15-25-8-6-18(19)22/h4-9,14-16H,10-13H2,1-3H3,(H,26,27show more
    Synonyms
    N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine
  4. Berzosertib, Serine-protein kinase ATR inhibitor
    CAS: 1232416-25-9 EC Number: 864-704-7 Formula: C24H25N5O3S Molecular Weight: 463.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: V275936
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    IUPAC Name
    3-[3-[4-(methylaminomethyl)phenyl]-1,2-oxazol-5-yl]-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
    SMILES
    CC(C)S(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C3=CC(=NO3)C4=CC=C(C=C4)CNC)N
    InChIKey
    JZCWLJDSIRUGIN-UHFFFAOYSA-N
    InChI
    1S/C24H25N5O3S/c1-15(2)33(30,31)19-10-8-18(9-11-19)21-14-27-24(25)23(28-21)22-12-20(29-32-22)17-6-4-16(5-7-17)13-26-3/h4-12,14-15,26H,13H2,1-3H3,(H2,2show more
    Synonyms
    5-(4-(isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine | CHEBI:131166 | M6...
  5. Harmol
    CAS: 487-03-6 Formula: C12H10N2O Molecular Weight: 198.23
    In Stock Item #: H156998
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    IUPAC Name
    1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one
    SMILES
    CC1=C2C(=C3C=CC(=O)C=C3N2)C=CN1
    InChIKey
    LBBJNGFCXDOYMQ-UHFFFAOYSA-N
    InChI
    1S/C12H10N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-6,13-14H,1H3
    Synonyms
    DTXSID10960989 | TNP00139 | NCGC00017250-02 | EINECS 207-645-9 | 7-Hydroxyharman | A1-00784 | HY-107811 | KBio2_00081...
  6. LDN-192960
    CAS: 184582-62-5 Formula: C18H20N2O2S Molecular Weight: 328.43
    In Stock Item #: L168104
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    IUPAC Name
    3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine
    SMILES
    COC1=CC2=C(C=C1)N=C3C=CC(=CC3=C2SCCCN)OC
    InChIKey
    ZFOMCSNUEHMROO-UHFFFAOYSA-N
    InChI
    1S/C18H20N2O2S/c1-21-12-4-6-16-14(10-12)18(23-9-3-8-19)15-11-13(22-2)5-7-17(15)20-16/h4-7,10-11H,3,8-9,19H2,1-2H3
    Synonyms
    AC-35777 | HY-13455 | BCP06879 | EX-A4806 | MFCD02752814 | CCRIS 8174 | 3-[(2,7-Dimethoxyacridin-9-yl)thio]propan-1-a...
  7. 3,5-Bis(2-fluorobenzylidene)piperidin-4-one
    CAS: 342808-40-6 EC Number: 686-985-3 Formula: C19H15F2NO Molecular Weight: 311.33
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B343498
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    IUPAC Name
    (3E,5E)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one;hydrochloride
    SMILES
    C1C(=CC2=CC=CC=C2F)C(=O)C(=CC3=CC=CC=C3F)CN1.Cl
    InChIKey
    ILMJCEBAMHGBAA-XETSTSIRSA-N
    InChI
    1S/C19H15F2NO.ClH/c20-17-7-3-1-5-13(17)9-15-11-22-12-16(19(15)23)10-14-6-2-4-8-18(14)21;/h1-10,22H,11-12H2;1H/b15-9+,16-10+;
    Synonyms
    3,5-Bis[(2-fluorophenyl)methylene]-4-piperidinone | (3E,5E)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one;hydro...
  8. Curcumin, Inhibitor of E1A binding protein p300;Activator of TRPV4
    CAS: 458-37-7 EC Number: 207-280-5 Formula: C21H20O6 Molecular Weight: 368.38
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    In Stock Item #: C110685
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    Technical Identifiers
    IUPAC Name
    (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
    SMILES
    COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
    InChIKey
    VFLDPWHFBUODDF-FCXRPNKRSA-N
    InChI
    1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
    Synonyms
    BIDD:ER0479 | Golden seal | NSC 687842 | Ukon (dye) | Victory 19 Virus Out | CURCUMIN (MART.) | Yellow Ginger | Zlut ...
  9. AZ 191, Inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1B
    CAS: 1594092-37-1 Formula: C24H27N7O Molecular Weight: 429.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421906
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    Technical Identifiers
    IUPAC Name
    N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
    SMILES
    CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=CC(=N3)C4=CN(C5=C4C=CN=C5)C)OC
    InChIKey
    ZYVXTMKTGDARKR-UHFFFAOYSA-N
    InChI
    1S/C24H27N7O/c1-29-10-12-31(13-11-29)17-4-5-21(23(14-17)32-3)28-24-26-9-7-20(27-24)19-16-30(2)22-15-25-8-6-18(19)22/h4-9,14-16H,10-13H2,1-3H3,(H,26,27show more
    Synonyms
    N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine
  10. Berzosertib, Serine-protein kinase ATR inhibitor
    CAS: 1232416-25-9 EC Number: 864-704-7 Formula: C24H25N5O3S Molecular Weight: 463.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: B421006
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    Technical Identifiers
    IUPAC Name
    3-[3-[4-(methylaminomethyl)phenyl]-1,2-oxazol-5-yl]-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
    SMILES
    CC(C)S(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C3=CC(=NO3)C4=CC=C(C=C4)CNC)N
    InChIKey
    JZCWLJDSIRUGIN-UHFFFAOYSA-N
    InChI
    1S/C24H25N5O3S/c1-15(2)33(30,31)19-10-8-18(9-11-19)21-14-27-24(25)23(28-21)22-12-20(29-32-22)17-6-4-16(5-7-17)13-26-3/h4-12,14-15,26H,13H2,1-3H3,(H2,2show more
    Synonyms
    5-(4-(isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine | CHEBI:131166 | M6...
  11. Curcumin
    CAS: 458-37-7 EC Number: 207-280-5 Formula: C21H20O6 Molecular Weight: 368.38
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Natural extraction(isomer mixture)
    In Stock Item #: C400222
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    Technical Identifiers
    IUPAC Name
    (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
    SMILES
    COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
    InChIKey
    VFLDPWHFBUODDF-FCXRPNKRSA-N
    InChI
    1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
    Synonyms
    BIDD:ER0479 | Golden seal | NSC 687842 | Ukon (dye) | Victory 19 Virus Out | CURCUMIN (MART.) | Yellow Ginger | Zlut ...
  12. Curcumin, Inhibitor of E1A binding protein p300;Activator of TRPV4
    CAS: 458-37-7 EC Number: 207-280-5 Formula: C21H20O6 Molecular Weight: 368.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: C408195
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    Technical Identifiers
    Synonyms
    Diferuloylmethane, Natural Yellow 3, Turmeric yellow | (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-...
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